Article
Biochemistry & Molecular Biology
Shahia Khattak, Xiao-Tong Qin, Long-Hui Huang, Yan-Yan Xie, Shi-Ru Jia, Cheng Zhong
Summary: The study prepared a hydrogel based on bacterial cellulose and chitosan, with the addition of silver sulfadiazine and crosslinked with glutaraldehyde. The incorporation of SSd significantly improved the mechanical and antibacterial properties of the hydrogel. The hydrogel showed higher toxicity to S. aureus than to E. coli.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Physical
Qian Dong, Fengling Yang, Feng Liang, Yan Zhang, Dehua Xia, Wei Zhao, Li Wu, Xueping Liu, Zhongfeng Jiang, Cheng Sun
Summary: Decahedral BiVO4 was successfully prepared at low temperature, forming BiVO4 nanosheet (S-BiVO4) through morphological changes in surfactant addition, which was then used to fabricate a series of Ag/S-BiVO4 plasmonic photocatalysts. Among them, Ag/4S-BiVO4 showed the highest photocatalytic performance, attributed to the SPR effect induced by silver nanoparticles.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Biotechnology & Applied Microbiology
Shahia Khattak, Xiao-Tong Qin, Fazli Wahid, Long-Hui Huang, Yan-Yan Xie, Shi-Ru Jia, Cheng Zhong
Summary: Surface oxidation of bacterial cellulose was carried out using the TEMPO-mediated oxidation mechanism, followed by impregnation with silver sulfadiazine to create nanocomposite membranes. Analysis using FTIR and XRD determined the presence of functional groups and crystallinity, while FESEM analysis showed the impregnation of nanoparticles and increased antibacterial activity with higher TOBC and AgSD content. This method retains and enhances the reactivity of BC, making it a promising option for biomedical applications such as wound dressing and tissue engineering.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Chemistry, Physical
Sirui He, Jia Liu, Shu He, An Liu, Wei Shao
Summary: In this study, a double crosslinking strategy was used to fabricate novel PGA sponges. The morphology and chemical composition of the sponges were characterized, and their antibacterial activity was evaluated. The results showed that the PGA sponges exhibited excellent antibacterial performance due to the release of silver sulfadiazine, and the release of sulfadiazine was diffusion controlled. These prepared PGA sponges showed improved mechanical properties and excellent antibacterial effects.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Review
Pharmacology & Pharmacy
Demis Ferreira de Melo, Gabryella Garcia Guedes, Livia Maria Coelho de Carvalho Moreira, Joao Augusto Oshiro-Junior, Bolivar Ponciano Goulart de Lima Damasceno
Summary: The use of antimicrobial agents in wound treatment is crucial for patient management, and silver sulfadiazine (AgSD) has been considered the gold standard due to its mechanism of action, efficacy, and safety. The combination of AgSD with polymers for curative formulations has been explored, and the evaluation of physical-chemical properties using analytical techniques is essential for determining their activities and detecting any incompatibilities. This review discusses the main physicochemical characterization techniques used in evaluating AgSD-containing systems, providing parameters for ensuring efficacy and safety.
CURRENT PHARMACEUTICAL DESIGN
(2023)
Article
Materials Science, Multidisciplinary
D. R. Assis, V. N. Ueyama, C. C. Santos, M. R. Davolos, M. Jafelicci Jr
Summary: This study demonstrates the in situ synthesis of 2D AgNPs through Langmuir-Blodgett (LB) technique using silver sulfadiazine (AgSD) and stearic acid (SA) as precursors. The use of NaBH4 for chemical reduction proves to be a more efficient method for the arrangement of Ag NPs compared to reduction under UV light.
Article
Endocrinology & Metabolism
Li Ma, Tingting Zou, Naixia Hu, Wenjing Pan
Summary: Silver sulfadiazine treatment significantly improves patients' quality of life, inhibits inflammatory reactions, and has a higher treatment efficacy and positive clinical value.
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
(2023)
Article
Biochemistry & Molecular Biology
Jean Lucas Tanaka, Caroline Barcelos Costa-Orlandi, Betina Sayeg Burd, Giovana Sant'Ana Pegorin, Thaina Venancio da Silva, Nayrim Brizuela Guerra, Maria Jose Soares Mendes-Giannini, Ana Marisa Fusco-Almeida, Rondinelli Donizetti Herculano, Natan Roberto de Barros
Summary: An inexpensive curative based on silver sulfadiazine (SS) and natural rubber latex (NRL) was developed to treat burn wounds, showing no interaction between drug and biopolymer in the infrared spectrum. The curative exhibited good mechanical properties, antifungal effects, and biocompatibility, representing a promising alternative for burn wound treatment.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Polymer Science
Doaa Alshora, Lubna Ashri, Rihaf Alfaraj, Ahlam Alhusaini, Raeesa Mohammad, Nawal Alanaze, Mohamed Ibrahim, Mohamed Badran, Mounir Bekhit, Shaikha Alsaif, Modhi Alagili, Rehab Ali, Adel Jreebi
Summary: This study aims to formulate a biofilm composed of silver sulfadiazine, chitosan, and sodium alginate, and evaluate its effectiveness in wound healing. The optimized formulation showed reasonable mechanical properties and significantly higher antibacterial activity compared to the blank biofilm. In vivo study demonstrated a 75% reduction in wound width with the formulated biofilm.
Article
Pharmacology & Pharmacy
Ruby Singh, Purandhi Roopmani, Meenakshi Chauhan, Suparna Mercy Basu, Waghela Deeksha, M. D. Kazem, Sarbani Hazra, Eerappa Rajakumara, Jyotsnendu Giri
Summary: In this study, dressing materials with dual properties of anti-bacterial and regenerative were developed for complex and large asymmetric burns. The results demonstrated sustained release of silver sulfadiazine (SSD) and concentration-dependent antibacterial activity. The airbrushed nanofibers showed biocompatibility, supported the differentiation and regeneration of cells, and facilitated complete recovery of burn wounds in rabbit models. The core-shell nanofibers displayed anti-inflammatory and proliferative activity without adverse tissue response.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2022)
Article
Environmental Sciences
Hongzhang Xu, Aaron Tang, Jamie Pittock
Summary: China's recent commitments to the Paris Agreement have raised concerns about their feasibility. In order to achieve carbon neutrality, China has implemented extreme emission reduction measures, but the side-effects of its climate ambition have been overlooked. An intersectional and just transitions perspective is needed to examine limitations and trade-offs for broader societal goals.
ENVIRONMENTAL RESEARCH LETTERS
(2021)
Article
Environmental Sciences
Ying Bai, Yanlei Zhou, Xiaowei Che, Conghe Li, Zhengguo Cui, Rongguo Su, Keming Qu
Summary: This study evaluated the impact of DOM composition on the indirect photolysis of SD, revealing that allochthonous humic-like components played a larger role in SD indirect photolysis. A significant relationship was found between the indirect photodegradation of SD and the decay of DOM fluorescent components, suggesting differences in SD indirect photolysis in various DOM solutions.
ENVIRONMENTAL POLLUTION
(2021)
Article
Oceanography
Ying Feng, Juncong Hu, Yongshan Chen, Jinghua Xu, Benfan Yang, Jinping Jiang
Summary: Antibiotics used in aquaculture can result in microbial adaptability and resistance, with the duration of aquaculture history playing a role. The microbial diversity in sediment with different aquaculture histories showed varying sensitivities to antibiotics. The function profiles of the bacterial community were influenced by antibiotic exposure.
OCEAN & COASTAL MANAGEMENT
(2022)
Article
Chemistry, Analytical
Xiaoling Zheng, Lulan Yang, Qi Sun, Lei Zhang, Tao Le
Summary: A fluorescent aptasensor based on MnO2 and FAM-labeled SDZ aptamer was developed for the detection of SDZ in food and environmental samples. The aptasensor exhibited high sensitivity and selectivity, and showed a good correlation with HPLC.
Article
Engineering, Environmental
Jing Chen, Kun Chu, Shiquan Sun, Hong Chen, Binghao Song, Jianhui Wang, Zidan Liu, Lei Zhu
Summary: In this research, a novel magnetic Fe3O4-Mn3O4 composite was synthesized and found to have higher catalytic performance for the degradation of sulfadiazine. The composite exhibited outstanding stability and good reusability. The degradation mechanism was confirmed to be the redox reactions between Mn(II)/Mn(III)/Mn(IV), Fe(II)/Fe(III), and the synergistic effect of Mn(III)/Fe(II).
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
