The P2Y13receptor regulates extracellular ATP metabolism and the osteogenic response to mechanical loading

Bones' adaptive response to mechanical loading is essentially linear between the low strains associated with disuse and the high strains associated with the lamellar/woven bone transition

(2012) Toshihiro Sugiyama et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Estrogen receptor-α is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not 2

(2012) Sara H Windahl et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Application of multiple forms of mechanical loading to human osteoblasts reveals increased ATP release in response to fluid flow in 3D cultures and differential regulation of immediate early genes

(2011) R.M.H. Rumney et al.   JOURNAL OF BIOMECHANICS

Effect of denosumab treatment on the risk of fractures in subgroups of women with postmenopausal osteoporosis

(2011) Michael R McClung et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Reduced Bone Turnover in Mice Lacking the P2Y13Receptor of ADP

(2011) Ning Wang et al.   MOLECULAR ENDOCRINOLOGY

Differential Gene Expression from Microarray Analysis Distinguishes Woven and Lamellar Bone Formation in the Rat Ulna following Mechanical Loading

(2011) Jennifer A. McKenzie et al.   PLoS One

P2Y13 receptor is critical for reverse cholesterol transport

(2010) Aurélie C. Fabre et al.   HEPATOLOGY

Early strain-related changes in enzyme activity in osteocytes following bone loading in vivo

(2010) Timothy M. Skerry et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committee

(2010) A. Michael Parfitt et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Guidelines for assessment of bone microstructure in rodents using micro-computed tomography

(2010) Mary L Bouxsein et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The mouse fibula as a suitable bone for the study of functional adaptation to mechanical loading

(2009) Alaa Moustafa et al.   BONE

Functional adaptation to mechanical loading in both cortical and cancellous bone is controlled locally and is confined to the loaded bones

(2009) Toshihiro Sugiyama et al.   BONE

ADP receptor P2Y13 induce apoptosis in pancreatic β-cells

(2009) Chanyuan Tan et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Hypoxia stimulates vesicular ATP release from rat osteoblasts

(2009) Isabel R. Orriss et al.   JOURNAL OF CELLULAR PHYSIOLOGY

P2X7and P2Y13purinergic receptors mediate intracellular calcium responses to BzATP in rat cerebellar astrocytes

(2009) Luz María G. Carrasquero et al.   JOURNAL OF NEUROCHEMISTRY

P2X7 receptor as sensitive flow sensor for ERK activation in osteoblasts

(2008) Hisashi Okumura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nucleotide- and nucleoside-converting ectoenzymes: Important modulators of purinergic signalling cascade

(2008) Gennady G. Yegutkin   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mechanical loading enhances the anabolic effects of intermittent parathyroid hormone (1–34) on trabecular and cortical bone in mice

(2008) Toshihiro Sugiyama et al.   BONE

Inhibiting Dickkopf-1 (Dkk1) Removes Suppression of Bone Formation and Prevents the Development of Osteolytic Bone Disease in Multiple Myeloma

(2008) Deborah J Heath et al.   JOURNAL OF BONE AND MINERAL RESEARCH

ECM Compliance Regulates Osteogenesis by Influencing MAPK Signaling Downstream of RhoA and ROCK

(2008) Chirag B Khatiwala et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Activation of extracellular-signal regulated kinase (ERK1/2) by fluid shear is Ca2+- and ATP-dependent in MC3T3-E1 osteoblasts

(2007) Dawei Liu et al.   BONE