Article
Health Care Sciences & Services
Fernanda Guedes Rodrigues, Rodrigo Fernandes Carvalho Azambuja Neves, Milene Subtil Ormanji, Priscila Ligeiro Goncalves Esper, Melissa Gaspar, Rosa Maria Rodrigues Pereira, Lucio R. Requiao-Moura, Martin H. de Borst, Ita Pfeferman Heilberg
Summary: This study suggests an association between reduced circulating Fet-A levels and increased bone Ct.Po with vascular calcification in stone formers.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Endocrinology & Metabolism
Saghi Sadoughi, Courtney Pasco, Gabby B. Joseph, Po-Hung Wu, Anne L. Schafer, Galateia J. Kazakia
Summary: This study found that patients undergoing RYGB surgery experienced significant increases in cortical porosity in the midcortical and periosteal layers of the tibia and radius at 12 months postoperatively, suggesting that the mechanism driving this increase is not primarily endosteal trabecularization.
JOURNAL OF BONE AND MINERAL RESEARCH
(2022)
Article
Agriculture, Dairy & Animal Science
Radoslaw P. Radzki, Marek Bienko, Dariusz Wolski, Pawel Polak
Summary: This study examines the influence of parental diet on the bone metabolism of offspring in later life. The researchers found that nutritional programming has a significant impact on the development and metabolism of the skeletal system in females during growth and maturity. Additionally, changing the caloric content of the diet can alter the metabolism of bone tissue and has varying osteotropic effects depending on the nature of the change and the stage of development.
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION
(2022)
Article
Gastroenterology & Hepatology
Gudmundur Vignir Sigurdsson, Susanne Schmidt, Dan Mellstrom, Claes Ohlsson, Robert Saalman, Mattias Lorentzon
Summary: Young adult men with childhood-onset IBD have decreased bone quality in both cortical and trabecular bone structures compared to age- and height-matched controls. This has implications for their skeletal health and quality of life.
INFLAMMATORY BOWEL DISEASES
(2023)
Article
Endocrinology & Metabolism
Anna L. Eriksson, Nele Friedrich, Magnus K. Karlsson, Osten Ljunggren, Mattias Lorentzon, Maria Nethander, Henri Wallaschofski, Dan Mellstrom, Claes Ohlsson
Summary: The study found that serum and urinary glycine levels are associated with bone mineral density, bone microstructure, and fracture risk in men. Serum glycine is inversely associated with femoral neck bone density and cortical bone strength in the distal tibia, while positively associated with fracture risk.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Biochemistry & Molecular Biology
Ivan Banovac, Lovorka Grgurevic, Viktorija Rumenovic, Slobodan Vukicevic, Igor Erjavec
Summary: Bone morphogenetic protein 3 (Bmp3) deletion was found to affect skeleton development until adulthood, leading to increased cortical and trabecular bone parameters in young and adult mice of both sexes, while delayed mineralization of the epiphyseal growth plate was observed in adult Bmp3(-/-) mice.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Endocrinology & Metabolism
Dominic Thewlis, Andrew Waters, Lucian B. Solomon, Egon Perilli
Summary: The study found significant correlations between joint loading during walking and subchondral volumetric bone mineral density (vBMD) measured by pQCT in healthy young individuals, providing new insights into joint mechanics research.
Article
Multidisciplinary Sciences
Liqin Zheng, Xiuhong Huang, Chihung Li, Pengfei Li, Ziling Lin, Shaohong Huang
Summary: The accuracy of 3D printed trabeculae in reproducing the mechanical properties of actual trabeculae was evaluated. The results showed that 3D printing can effectively replicate the mechanical properties of actual trabeculae, with the best results observed at a magnification of 3x, 4x, and 5x.
Article
Biology
Deyin Kong, Qing Wang, Jiangeng Huang, Zhihui Zhang, Xiebin Wang, Qing Han, Yanbin Shi, Ran Ji, Yiling Li
Summary: This study investigates the mechanical properties and bone reconstruction performance of bionic bone scaffolds, focusing on those that mimic the structural features of natural cancellous bone. The results show that bionic scaffolds with specific structural parameters perform well in bone defect reconstruction and have potential for clinical application.
COMPUTERS IN BIOLOGY AND MEDICINE
(2023)
Article
Endocrinology & Metabolism
Lauren M. Coheley, Mengyun Yu, Xianyan Chen, Patrick J. O'Connor, Kirk S. Kealey, Emma M. Laing, Assaf Oshri, Alicia K. Marand, Julia M. Lance, Joseph M. Kindler, Richard D. Lewis
Summary: The effects of consuming 8-10 eggs per week for 9 months in children entering the early stages of puberty on bone health are small.
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Review
Biochemistry & Molecular Biology
Tsuyoshi Isojima, Natalie A. Sims
Summary: The article discusses the mechanisms of cortical bone development, growth, and degeneration, as well as genetic modifications and sex-specific differences. With aging, the process of consolidation reverses, leading to cortical porosity and loss of bone strength. These processes require coordination between cell-specific signaling pathways.
CELLULAR AND MOLECULAR LIFE SCIENCES
(2021)
Article
Orthopedics
Julian Stuerznickel, Nico Hinz, Maximilian M. Delsmann, Tim Hoenig, Tim Rolvien
Summary: This cross-sectional study characterized the bone microarchitecture in athletes with bone stress injuries and found reduced bone mineral density and impaired cortical bone microarchitecture in many athletes. However, neither bone mineral density nor bone microarchitecture was related to the injury site, highlighting the multifactorial etiology of bone stress injuries.
AMERICAN JOURNAL OF SPORTS MEDICINE
(2022)
Article
Endocrinology & Metabolism
Alex Ireland, Amy Riddell, Ann Prentice, Judith Eelloo, M. Zulf Mughal, Kate A. Ward
Summary: Children with NF1 have slower bone mass accrual in the tibia and fibula compared to control children, which is partly related to deficits in longitudinal growth and body weight. Interventions promoting muscle development or physical activity may help attenuate bone mass accrual deficits in this population.
Article
Endocrinology & Metabolism
S. Sharma, P. Mehta, A. Patil, S. K. Gupta, S. Rajender, N. Chattopadhyay
Summary: Through meta-analyses, it has been found that dialysis patients have compromised bone health compared to healthy controls, with lower bone mass and deterioration in bone microarchitecture. Tibial vBMD may be used as a diagnostic indicator for dialysis patients. HR-pQCT and pQCT can provide further understanding of the bone response to CKD-induced loss at different stages.
OSTEOPOROSIS INTERNATIONAL
(2022)
Article
Orthopedics
Camille P. Figueiredo, Mariana O. Perez, Lucas Peixoto Sales, Ana Cristina Medeiros, Valeria F. Caparbo, Rosa M. R. Pereira
Summary: This study found that BMD of MCP head was independently associated with the volume of bone erosion, suggesting it can be used to analyze and monitor bone destruction, as well as to evaluate treatment response in RA patients.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Endocrinology & Metabolism
Lewan Parker, Xuzhu Lin, Andrew Garnham, Glenn McConell, Nigel K. Stepto, David L. Hare, Elizabeth Byrnes, Peter R. Ebeling, Ego Seeman, Tara C. Brennan-Speranza, Itamar Levinger
JOURNAL OF BONE AND MINERAL RESEARCH
(2019)
Article
Endocrinology & Metabolism
Roger Zebaze, Marit Osima, Minh Bui, Marko Lukic, Xiaofang Wang, Ali Ghasem-Zadeh, Erik F. Eriksen, Angela Vais, Catherine Shore-Lorenti, Peter R. Ebeling, Ego Seeman, Ashild Bjornerem
JOURNAL OF BONE AND MINERAL RESEARCH
(2019)
Article
Endocrinology & Metabolism
Roland Chapurlat, Minh Bui, Elisabeth Sornay-Rendu, Roger Zebaze, Pierre D. Delmas, Danny Liew, Eric Lespessailles, Ego Seeman
JOURNAL OF BONE AND MINERAL RESEARCH
(2020)
Article
Endocrinology & Metabolism
Ada S. Cheung, Rudolf Hoermann, Ali Ghasem-Zadeh, Alistair J. Tinson, Vivian Ly, Stefan Milevski, Daryl Lim Joon, Jeffrey D. Zajac, Ego Seeman, Mathis Grossmann
JOURNAL OF BONE AND MINERAL RESEARCH
(2020)
Article
Endocrinology & Metabolism
Ali Ghasem-Zadeh, Mary P. Galea, Andrew Nunn, Maya Panisset, Xiao-Fang Wang, Sandra Iuliano, Steven K. Boyd, Mark R. Forwood, Ego Seeman
Summary: Patients with tetraplegia and paraplegia display significant deficits in bone mineral density, with varying differences observed among different regions of the body.
Review
Endocrinology & Metabolism
T. John Martin, Natalie A. Sims, Ego Seeman
Summary: PTH and PTHrP share a common G protein-coupled receptor, but have different physiological and pharmacological effects. PTHrP is essential for fetal bone development, while PTH mainly regulates calcium homeostasis. Both peptides have anabolic effects on bone formation pharmacologically.
Article
Cell & Tissue Engineering
Kylie Crompton, Iona Novak, Michael Fahey, Nadia Badawi, Katherine J. Lee, Francoise Mechinaud-Heloury, Priya Edwards, Paul Colditz, Trisha Soosay Raj, Janet Hough, Xiaofang Wang, Simon Paget, Kuang-Chih Hsiao, Peter Anderson, Dinah Reddihough
Summary: This study investigated the safety and preliminary efficacy of sibling cord blood cell infusion in children with cerebral palsy. The findings suggest that sibling cord blood cell infusion is relatively safe for children with cerebral palsy when conducted in appropriate facilities, but the improvement in motor function and upper extremity skills is limited.
Article
Medicine, General & Internal
Peter A. Dargaville, C. Omar F. Kamlin, Francesca Orsini, Xiaofang Wang, Antonio G. De Paoli, H. Gozde Kanmaz Kutman, Merih Cetinkaya, Lilijana Kornhauser-Cerar, Matthew Derrick, Hilal Ozkan, Christian Hulzebos, Georg M. Schmolzer, Ajit Aiyappan, Brigitte Lemyre, Sheree Kuo, Victor S. Rajadurai, Joyce O'Shea, Manoj Biniwale, Rangasamy Ramanathan, Alla Kushnir, David Bader, Mark R. Thomas, Mallinath Chakraborty, Mariam J. Buksh, Risha Bhatia, Carol L. Sullivan, Eric S. Shinwell, Amanda Dyson, David P. Barker, Amir Kugelman, Tim J. Donovan, Markus K. Tauscher, Vadivelam Murthy, Sanoj K. M. Ali, Pete Yossuck, Howard W. Clark, Roger F. Soll, John B. Carlin, Peter G. Davis
Summary: This study aimed to examine the effect of selective application of minimally invasive surfactant therapy on preterm infants with respiratory distress syndrome. The results showed that while there was no significant difference between the MIST group and the control group in terms of death or bronchopulmonary dysplasia at 36 weeks' postmenstrual age, the incidence of BPD in survivors was lower in the MIST group.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2021)
Article
Endocrinology & Metabolism
Ingrid Bretherton, Ali Ghasem-Zadeh, Shalem Y. Leemaqz, Ego Seeman, Xiaofang Wang, Thomas McFarlane, Cassandra Spanos, Mathis Grossmann, Jeffrey D. Zajac, Ada S. Cheung
Summary: This study compared bone microarchitecture between transgender individuals receiving gender-affirming hormone therapy and control groups. The results showed that trans men had higher bone density and thickness, while trans women had lower bone density, thickness, and trabecular volume.
JOURNAL OF BONE AND MINERAL RESEARCH
(2022)
Article
Pediatrics
Ben Gelbart, Brent McSharry, Carmel Delzoppo, Simon Erickson, Katherine Lee, Warwick Butt, Miriam Rea, Xiaofang Wang, John Beca, Alex Kazemi, Frank Shann
Summary: The study aimed to investigate whether the combination of systemic corticosteroids and nebulized epinephrine can reduce the duration of positive pressure support in children with bronchiolitis admitted to intensive care compared with standard care. The results showed that regular treatment with systemic corticosteroids and inhaled epinephrine significantly reduced the duration of clinician-managed pressure support in children with severe bronchiolitis.
JOURNAL OF PEDIATRICS
(2022)
Article
Medicine, General & Internal
S. Iuliano, S. Poon, J. Robbins, M. Bui, X. Wang, L. De Groot, M. Van Loan, A. Ghasem Zadeh, T. Nguyen, E. Seeman
Summary: This study aimed to assess the antifracture efficacy and safety of a nutritional intervention in institutionalized older adults with adequate vitamin D levels but low calcium and protein intakes. The intervention group, which received additional dairy foods, showed significant reductions in the incidence of fractures and falls, with no significant impact on all-cause mortality. The results suggest that improving calcium and protein intake through dairy foods is an effective intervention to reduce the risk of falls and fractures in aged care residents.
BMJ-BRITISH MEDICAL JOURNAL
(2021)
Meeting Abstract
Endocrinology & Metabolism
R. Zebaze, E. J. Atkinson, Y. Peng, M. Bui, A. Ghasem-Zadeh, S. Khosla, E. Seeman
OSTEOPOROSIS INTERNATIONAL
(2019)
Meeting Abstract
Endocrinology & Metabolism
E. Seeman, S. Ferrari
OSTEOPOROSIS INTERNATIONAL
(2019)
Article
Nutrition & Dietetics
Yusi Liu, Shirley Poon, Ego Seeman, David L. Hare, Minh Bui, Sandra Iuliano
JOURNAL OF NUTRITIONAL SCIENCE
(2019)