Article
Multidisciplinary Sciences
Mateus Augusto Bim, Andre de Araujo Pinto, Hector Cris Colares de Angelo, Isadora Gonzaga, Adriana Coutinho de Azevedo Guimaraes, Erico Pereira Gomes Felden, Wellington Roberto Gomes de Carvalho, Karen Hind, Andreia Pelegrini
Summary: This study aimed to assess the relationship between bone mass and lean mass (LM) and fat mass (FM) in normal-weight and overweight adolescents. The results showed that only LM was associated with bone mass in both normal-weight and overweight adolescents. LM was found to be the main predictor of bone mass in these groups.
Article
Medicine, General & Internal
Di Yang, Yafen Ye, Yinfang Tu, Rongrong Xu, Yunfeng Xiao, Hongwei Zhang, Weijie Liu, Pin Zhang, Haoyong Yu, Yuqian Bao, Junfeng Han
Summary: This study aimed to investigate the sex-specific changes in bone mineral density (BMD) following sleeve gastrectomy and evaluate the role of sex hormone-binding globulin (SHBG) in this process. The results showed significant differences in BMD changes between sexes, with men having a greater reduction in total hip BMD and less increase in SHBG after sleeve gastrectomy than women. SHBG was significantly associated with total hip BMD loss in men, while total estrogen was significantly associated with total hip BMD loss in women. These findings suggest the importance of sex-specific screening for personalized postoperative bone care in this population.
FRONTIERS IN MEDICINE
(2022)
Article
Endocrinology & Metabolism
Ke Xu, Yicheng Fu, Buzi Cao, Mingyi Zhao
Summary: This study aims to evaluate the association between sex hormones and sex hormone-binding globulin (SHBG) with bone mineral density (BMD) in adolescents. The results show differences in the association of sex hormones with BMD in boys and girls, where an appropriate increase in serum testosterone levels may be beneficial for skeletal development in girls and keeping estradiol levels below a certain level in boys may be considered.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Pediatrics
Samantha Lopez-Peralta, Enrique Romero-Velarde, Edgar M. Vasquez-Garibay, Mercedes Gonzalez-Hita, Laura C. Robles-Robles, Francisco J. Ruiz-Gonzalez, Misael Alejandro Perez-Romero
Summary: This study explores the relationship between bone mineral density (BMD) and body composition in children of different weight categories. The results show that BMD is higher in obese children compared to normal weight children, which can be attributed to their greater lean mass rather than excess body fat. However, a higher fat mass in obese children is associated with lower lumbar spine BMD. Lean mass is directly correlated with BMD in all weight groups and is the most important predictor of BMD.
Article
Multidisciplinary Sciences
Stephen Clive Hayes, Matthew White, Christopher Richard James Wilcox, Hollie Samantha Forbes White, Natalie Vanicek
Summary: This study compared the biomechanical profiles of individuals with spinal cord injury (SCI) and able-bodied individuals inside the ReWalk (TM) powered exoskeleton. The study found differences in joint angles between the SCI group and the able-bodied group, but using the ReWalk (TM) device for upright walking was able to activate central pattern generators (CPGs).
Article
Endocrinology & Metabolism
Aaron Misakian, Michelle McLoughlin, Louisa C. Pyle, Thomas F. Kolon, Andrea Kelly, Maria G. Vogiatzi
Summary: This study investigated bone mineral density and body composition in adolescents with CAIS, showing a bone mass deficit in this population. Further research is needed to understand the extent of BMD abnormalities, the impact of early gonadectomy, and the optimal hormone replacement therapy regimen for bone accrual. Data on lean mass were reassuring.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Endocrinology & Metabolism
Ruth Durdin, Camille Parsons, Elaine M. Dennison, Suzanne Williams, Therese Tillin, Nishi Chaturvedi, Cyrus Cooper, Nicholas C. Harvey, Kate A. Ward
Summary: The study aimed to investigate whether central adiposity or inflammatory status contribute to ethnic differences in bone mineral density (BMD). The study found that despite adjustment for body composition, central adiposity, and inflammation, ethnic differences in BMD still existed. Additionally, ethnic differences were observed in the relationship between BMI, LMI or VAT mass and lumbar spine BMD in women.
Article
Endocrinology & Metabolism
H. -T. Ning, Y. Du, L. -J. Zhao, Q. Tian, H. Feng, H. -W. Deng
Summary: The study found that there are racial and gender differences in the relationship between sarcopenia and BMD among older adults. Sarcopenic individuals are more likely to have lower BMD, with the strongest association found in non-Hispanic Black people, followed by non-Hispanic White people and non-Hispanic Asian people. Adjustments for physiological, behavioral, and disease factors were made, and it was concluded that consideration in race and sex is important when developing strategies to maintain or minimize BMD loss.
OSTEOPOROSIS INTERNATIONAL
(2021)
Article
Medicine, General & Internal
Zhenwei Wang, Weibin Du, Meichun Han, Lihong He, Hongwei Zhang, Jintao Hu, Renfu Quan
Summary: Our study found that creatine phosphokinase (CPK) has a positive impact on bone mineral density (BMD) in adolescents, especially in boys aged 16 to 19. This suggests that CPK may serve as a potential biomarker of bone health among adolescents.
Article
Endocrinology & Metabolism
Carmen Valero, Jose Manuel Olmos, Ludovic Humbert, Jesus Castillo, Jose Luis Hernandez, Josefina Martinez, Jesus Gonzalez Macias
Summary: Although women have lower areal BMD compared to men, our study shows that women <= 59 years have a hip volumetric BMD by DXA 3D similar to that of men of the same age. Taking into account bone size is important when analyzing sex-related differences in bone mass.
ARCHIVES OF OSTEOPOROSIS
(2021)
Article
Multidisciplinary Sciences
M. E. Bayartai, C. E. Schaer, Hannu Luomajoki, G. Tringali, R. De Micheli, A. Sartorio
Summary: This study aimed to investigate the association between obesity and spinal posture and mobility in children and adolescents. The results showed that obese individuals had greater thoracic kyphosis and extension, as well as decreased mobility in various spinal movements compared to normal-weight individuals.
SCIENTIFIC REPORTS
(2022)
Article
Pediatrics
Pat R. Vehrs, Haley Barker, Misea Nomiyama, Zachary Vehrs, Miklos Toth, Martina Uvacsek, Ulrike H. Mitchel, Aaron W. Johnson
Summary: The study evaluated functional movement performance and asymmetry epidemiology in children, finding that girls had higher average FMS scores than boys, and most children have movement limitations.
Article
Gastroenterology & Hepatology
Binghan Jin, Zhaoyuan Wu, Shan Wang, Zhu Yu, Rahim Ullah, Xinyi Liang, Wei Wu, Ke Huang, Yan Ni, Jianbing Wang, Guanping Dong, Junfen Fu
Summary: This study examines the prevalence of non-alcoholic fatty liver disease (NAFLD) in obese Chinese children and investigates the relationship between sex hormones and NAFLD. The study finds a significant difference in NAFLD prevalence between genders in obese children, which is influenced by age, Tanner stage, and fat distribution. Sex hormones are associated with NAFLD prevalence in a gender-specific manner.
HEPATOLOGY INTERNATIONAL
(2023)
Article
Endocrinology & Metabolism
Hai-yan Huang, Zhi-qi Huang, Ling-yan Hua, Wang-shu Liu, Feng Xu, Xiao-qin Ge, Chun-feng Lu, Jian-bin Su, Xue-qin Wang
Summary: The study found a significant association between low-normal serum sodium levels and low bone turnover, as well as a positive correlation between high serum sodium levels and high bone turnover.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Michael Schonemann Rand, Sarah Seberg Diemar, Line Tang Mollehave, Malene Heidemann, Betina Heinsbaek Thuesen, Jorgen Holm Petersen, Jesper Johannesen, Anders J. Schou, Niels Wedderkopp, Christian Molgaard, Niklas Rye Jorgensen
Summary: The objective of this study was to establish sex- and age-specific reference curves for bone turnover markers (BTM) and to examine their association with change in total body less head bone mineral density (TBLH BMD) in children and adolescents. The results showed that BTM levels peak at the age of 11 to 12 years in girls and 13 to 14 years in boys, corresponding to the age at peak height velocity. BTM Z-scores were positively associated with change in TBLH BMD Z-score.