Article
Biochemistry & Molecular Biology
Tao Liu, Binglin Li, Gang Chen, Xiangling Ye, Ying Zhang
Summary: Research on 3D printed scaffolds doped with nano tantalum shows potential in improving bone defect treatment by enhancing bioactivity and osteogenesis.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Nanoscience & Nanotechnology
Zongbao Liu, Guanghui Jia, Yang Xu, Mu Hu
Summary: This study aimed to evaluate the effect of BMP-7 loaded nano-CaP coated PTS on the regeneration and repair of cartilage defects in rabbits. The results showed that CaP/PTS loaded with BMP-7 significantly enhanced the regenerative and reparative potency of cartilage defects.
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Monika Biernat, Aleksandra Szwed-Georgiou, Karolina Rudnicka, Przemyslaw Plocinski, Joanna Pagacz, Paulina Tymowicz-Grzyb, Anna Wozniak, Marcin Wlodarczyk, Mateusz M. Urbaniak, Agnieszka Krupa, Paulina Rusek-Wala, Natalia Karska, Sylwia Rodziewicz-Motowidlo
Summary: This study investigates a novel two-step modification strategy to improve the compatibility and mechanical strength of composite materials for bone regeneration. The modified composite shows promising potential for biomedical engineering applications.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Multidisciplinary Sciences
Zahra Ebrahimi, Shiva Irani, Abdolreza Ardeshirylajimi, Ehsan Seyedjafari
Summary: Bone tissue engineering uses different methods and materials to find suitable scaffolds for bone regeneration. This study aimed to enhance bone formation, osteogenic differentiation, and in vitro biocompatibility by modifying poly(epsilon-caprolactone) (PCL) scaffolds with hydroxyapatite (HA) and collagen type I (COL). The results showed that coating the scaffolds with HA and COL can boost the proliferation and differentiation of human adipose tissue-derived mesenchymal stem cells (hADSCs) in a synergistic manner. The tricomponent 3D-printed scaffold is considered promising for bone tissue regeneration and rebuilding.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Lijia Cheng, Tianchang Lin, Ahmad Taha Khalaf, Yamei Zhang, Hongyan He, Liming Yang, Shuo Yan, Jiang Zhu, Zheng Shi
Summary: The study developed an artificial bone material with excellent mechanical properties and good osteogenic capability, which showed better bone tissue regeneration and repair effects in mice compared to the control group. The CTC composites have proven to be a promising option for orthopedic patients.
SCIENTIFIC REPORTS
(2021)
Article
Chemistry, Physical
Alison. L. White, Hazel A. Javier, Sarah Withey, Simon R. Biggs, Stephen Rose, Simon G. Puttick, Andrew K. Whittaker
Summary: Efficient encapsulation of small molecule active ingredients has been a challenge in various commercial applications. A new method using thin mineral shells to protect active ingredients was developed. The majority of the microcapsules formed a non-porous protective shell, with only the defective ones releasing small concentrations of the core material.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Materials Science, Coatings & Films
Wei-Ting Ting, Tzu-Hsien Yang, Yuan Cheng, Ko-Shao Chen, Shiu-Huey Chou, Mu-Rong Yang, Meng-Jiy Wang
Summary: A composite material combining calcium phosphate and plasma polymerized HMDSZ has been developed to enhance osteoconduction and corrosion resistance. Modulating the amount of Ca-P coatings showed positive cell responses towards surface wettability and roughness. The combination of bioceramics and corrosion resistant plasma polymerized HMDSZ films exhibited synergistic effects on biocompatibility and osteoconductivity for bone tissue engineering applications.
SURFACE & COATINGS TECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Long Hua, Hu Qian, Ting Lei, Yu Zhang, Pengfei Lei, Yihe Hu
Summary: The treatment of bone and joint tuberculosis remains challenging, but the development of tissue-engineered drug-loaded biomaterials has provided new therapeutic options. These bio-scaffolds exhibit good biocompatibility, slow drug release, and bone regeneration capabilities, making them a promising approach for the treatment of bone and joint tuberculosis.
MACROMOLECULAR BIOSCIENCE
(2022)
Article
Engineering, Biomedical
Agneta Vezenkova, Janis Locs
Summary: With the increase in global population, the demand for bone substitutes is growing. Calcium phosphate cements (CPCs) have the potential for various applications in bone regeneration due to their ability to self-set and resorb. However, finding an osteoinductive material that is suitable for injection remains a challenge.
BIOACTIVE MATERIALS
(2022)
Article
Thermodynamics
Ahmet Alperen Gunay, Sivasankaran Harish, Masanori Fuchi, Ikuya Kinefuchi, Yaerim Lee, Junichiro Shiomi
Summary: We demonstrate a novel strategy to enhance the thermoelectric conversion efficiency by utilizing the latent heat of atmospheric water, radiative cooling, and an enhanced surface area. Coating porous copper substrates with metal-organic frameworks significantly increases the heat transfer efficiency, leading to a substantial increase in the total electromotive force generated by the thermoelectric generator within 30 minutes.
ENERGY CONVERSION AND MANAGEMENT
(2022)
Article
Pharmacology & Pharmacy
Xuechun Zhao, Liming Zhu, Changchun Fan
Summary: The study utilized An-MNS-HA nanomaterial to effectively reduce bacterial infection and increase proliferation and differentiation of human primary osteoblasts cells. This nanomaterial displayed antibacterial activity, low toxicity, and ability to induce ossification, showing promise for accelerating bone fracture healing and repair of bone defects.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2021)
Article
Materials Science, Multidisciplinary
Jung-Eun Park, Yong-Seok Jang, Seo -Young Kim, Ji-Bong Choi, Tae-Sung Bae, Il -Song Park, Min -Ho Lee
Summary: This study demonstrated that coating biodegradable magnesium with calcium phosphate doped strontium can improve its bioactivity and corrosion resistance, preventing damage and corrosion of the magnesium surface while promoting cell proliferation. The in vivo implantation experiment also confirmed the positive effect of modified magnesium on bone regeneration.
MATERIALS TODAY COMMUNICATIONS
(2022)
Article
Engineering, Biomedical
Jiantong Cui, Shaoqing Zhang, Meng Huang, Xiaodan Mu, Junhao Hei, Vicky Yau, Huixia He
Summary: This study successfully prepared a micro-nano porous structured tantalum coating on titanium using vacuum plasma spraying. The tantalum-coated titanium dental implants showed superior surface properties and biocompatibility compared to other materials. The tantalum coating promoted the adhesion, proliferation, and osteogenic differentiation of bone marrow mesenchymal cells, as well as demonstrated positive osseointegration capability in vivo.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
(2023)
Article
Materials Science, Ceramics
Nur Zulaikha Mohamad Zaidi, Ahmed Hafedh Mohammed Mohammed, Mamun Khan Sujon, Khairul Anuar Shariff, Mohamad Hafizi Abu Bakar
Summary: The present study investigated the behavior of bone-like cells towards dense and porous dicalcium phosphate dihydrate (DCPD)-coated & beta;-tricalcium phosphate (& beta;-TCP) granules. The results demonstrated that the DCPD-coated porous & beta;-TCP granules contributed to the release of calcium ions and decreased pH values. Furthermore, these granules showed good initial cell attachment and enhanced cell viability for up to three days. These findings provide new insights into the impact of pore presence on accelerating cell responses to DCPD-coated & beta;-TCP granules for bioceramic researchers.
JOURNAL OF THE AUSTRALIAN CERAMIC SOCIETY
(2023)
Article
Biotechnology & Applied Microbiology
Xin Chen, Jiajun Yan, Yingying Jiang, Yunshan Fan, Zhengran Ying, Shuo Tan, Zhi Zhou, Junjian Liu, Feng Chen, Shisheng He
Summary: This study presents a biomimetic strategy for developing an injectable biomaterial composed of platelets, fibrins, and biominerals to repair bone defects. The biomaterial showed high biocompatibility and promoted the osteogenic differentiation of bone marrow stem cells. In vivo studies demonstrated that the biomaterial induced the formation of new collagen and blood vessels, leading to faster bone defect regeneration. This research provides a strategy for designing new biomimetic materials and holds significant importance for the treatment of refractory bone fractures.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Correction
Orthopedics
Nemandra A. Sandiford, Peter Misur, Donald S. Garbuz, Nelson V. Greidanus, Bassam A. Masri
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
(2018)
Article
Orthopedics
Brett K. J. Kilb, Andrew P. Kurmis, Michael Parry, Karen Sherwood, Paul Keown, Bassam A. Masri, Clive P. Duncan, Donald S. Garbuz
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
(2018)
Article
Orthopedics
Amir Herman, Anthony Albers, Donald S. Garbuz, Clive P. Duncan, Bassam A. Masri
Article
Orthopedics
Amir Herman, Bassam A. Masri, Clive P. Duncan, Nelson V. Greidanus, Donald S. Garbuz
Review
Orthopedics
Andrew P. Kurmis, Amir Herman, Adam R. McIntyre, Bassam A. Masri, Donald S. Garbuz
JOURNAL OF ARTHROPLASTY
(2019)
Article
Orthopedics
M. El-Hussein, B. Masri, C. Duncan, D. S. Garbuz
BONE & JOINT JOURNAL
(2019)
Article
Engineering, Biomedical
Qiong Wang, Felipe Eltit, Donald Garbuz, Clive Duncan, Bassam Masri, Nelson Greidanus, Rizhi Wang
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
(2020)
Editorial Material
Orthopedics
F. S. Haddad, B. A. Masri
BONE & JOINT JOURNAL
(2019)
Review
Orthopedics
Gerard A. Sheridan, Donald S. Garbuz, Bassam A. Masri
Summary: Recent evidence suggests a significantly lower failure rate for hybrid stems in revision TKA, with a trend favoring their use for all outcome variables assessed in this study. These findings support the recommendation for the use of hybrid stems in revision TKA whenever possible.
EUROPEAN JOURNAL OF ORTHOPAEDIC SURGERY AND TRAUMATOLOGY
(2021)
Review
Orthopedics
Aresh Sepehri, Arashdeep Sidhu, Bassam A. Masri
Summary: Total hip arthroplasty (THA) is increasingly being used for managing osteoarthritis of the hip in patients with fragile or pathologic bone, thanks to advances in surgical technique and implant design. Surgeons should be prepared to evaluate and manage intraoperative iatrogenic fracture in patients with posttraumatic or congenital deformities associated with fragile or pathologic bone. Although evidence is limited, components made with computer-assisted design can be considered for this unique and highly variable patient population.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
(2021)
Article
Orthopedics
D. J. Stockton, A. M. Schmidt, A. Yung, J. Desrochers, H. Zhang, B. A. Masri, D. R. Wilson
Summary: ACL rupture leads to increased contact area, posteriorly translated medial centroid, anterior tibial translation, and reduced tibial external rotation, regardless of surgical reconstruction status. These changes persist 2.7 years post-injury.
BONE & JOINT JOURNAL
(2021)
Letter
Orthopedics
Matthew D. Hickey, Carolyn Anglin, Bassam Masri, Antony J. Hodgson
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
(2022)
Article
Orthopedics
G. A. Sheridan, M. Hanlon, A. Welch-Phillips, K. Spratt, R. Hagan, J. M. O'Byrne, P. J. Kenny, A. P. Kurmis, B. A. Masri, D. S. Garbuz, C. J. Hurson
Summary: This case-control study found an association between specific HLA genotypes and the development of pseudotumours around metal-on-metal hip resurfacing procedures. Specifically, the HLA-DQB1* 05:03:01 and HLA-DRB1* 14:54:01 alleles were significantly associated with a higher risk of pseudotumour formation.
Article
Orthopedics
G. A. Sheridan, R. Moshkovitz, B. A. Masri
Summary: Simultaneous bilateral TKA can be used as an effective teaching model for trainees without any significant impact on patient clinical or functional outcomes. Excellent functional and clinical outcomes in both knees, regardless of whether the performing surgeon is a trainee or supervising surgeon, can be achieved with simultaneous bilateral TKA.
Article
Management
Kyle W. Demes, Gail C. Murphy, Helen M. Burt
JOURNAL OF RESEARCH ADMINISTRATION
(2019)