期刊
JOURNAL OF BIOSCIENCE AND BIOENGINEERING
卷 107, 期 1, 页码 7-9出版社
SOC BIOSCIENCE BIOENGINEERING JAPAN
DOI: 10.1016/j.jbiosc.2008.08.001
关键词
Mortierella alpina; omega 3 desaturase; Mutant; Polyunsaturated fatty acid; Filamentous fungus; Mutation site
资金
- Ministry of Education, Science, Sports, and Culture of Japan [15658024]
- MicrobialProcess Development Pioneering Future Production Systems
- New Energy and Industrial Technology Development Organization of Japan [05A07003d]
The mutation sites on omega 3 desaturase genes in two omega 3 desaturase-defective mutants derived from arachidonic acid-producing Mortierella alpina 1S-4 were identified. The mutations each resulted in an amino acid replacement (W232Stop or W386Stop) which caused a lack of omega 3 desaturase activity in these mutants. (C) 2008, The Society for Biotechnology, Japan. All rights reserved.
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