期刊
JOURNAL OF BIOSCIENCE AND BIOENGINEERING
卷 108, 期 5, 页码 446-449出版社
SOC BIOSCIENCE BIOENGINEERING JAPAN
DOI: 10.1016/j.jbiosc.2009.05.005
关键词
Chromatin structure; Purification; iChlP; Epigenetics; Transcriptional regulation
We established a novel method, insertional chromatin immunoprecipitation (iChlP), for isolation of specific genomic regions. In iChlP, specific genomic domains are immunoprecipitated with antibody against a tag, which is fused to the DNA-binding domain of an exogenous DNA-binding protein, whose recognition sequence is inserted into the genomic domains of interest. The iChlP method will be a useful tool for dissecting chromatin structure of genomic region of interest. (C) 2009, The Society for Biotechnology, Japan. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据