Molecular dynamics simulations show how the FMRP Ile304Asn mutation destabilizes the KH2 domain structure and affects its function

New perspectives on the biology of fragile X syndrome

(2012) Tao Wang et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Docking Simulation and Competitive Experiments Validate the Interaction Between the 2,5-Xylidine Inhibitor andRigidoporus lignosusLaccase

(2012) Maria Teresa Cambria et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Fragile X syndrome: causes, diagnosis, mechanisms, and therapeutics

(2012) Claudia Bagni et al.   JOURNAL OF CLINICAL INVESTIGATION

FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism

(2011) Jennifer C. Darnell et al.   CELL

Reversible Inhibition of PSD-95 mRNA Translation by miR-125a, FMRP Phosphorylation, and mGluR Signaling

(2011) Ravi S. Muddashetty et al.   MOLECULAR CELL

ADP/ATP mitochondrial carrier MD simulations to shed light on the structural–dynamical events that, after an additional mutation, restore the function in a pathological single mutant

(2010) Daniele Di Marino et al.   JOURNAL OF STRUCTURAL BIOLOGY

A Functional Requirement for PAK1 Binding to the KH(2) Domain of the Fragile X Protein-Related FXR1

(2010) Evonne Say et al.   MOLECULAR CELL

Regulation of Synaptic Structure and Function by FMRP-Associated MicroRNAs miR-125b and miR-132

(2010) Dieter Edbauer et al.   NEURON

Dali server: conservation mapping in 3D

(2010) Liisa Holm et al.   NUCLEIC ACIDS RESEARCH

A study of the ultrastructure of Fragile-X-related proteins

(2009) Ljiljana Sjekloća et al.   BIOCHEMICAL JOURNAL

DichroCalc--circular and linear dichroism online

(2009) B. M. Bulheller et al.   BIOINFORMATICS

The Fragile X Syndrome Protein Represses Activity-Dependent Translation through CYFIP1, a New 4E-BP

(2008) Ilaria Napoli et al.   CELL

Structure and function of KH domains

(2008) Roberto Valverde et al.   FEBS Journal

Thr729 in human topoisomerase I modulates anti-cancer drug resistance by altering protein domain communications as suggested by molecular dynamics simulations

(2008) Giovanni Chillemi et al.   NUCLEIC ACIDS RESEARCH