Article
Chemistry, Analytical
Maha K. Rahim, Jinghui Zhao, Hinesh V. Patel, Hauna A. Lagouros, Rajesh Kota, Irma Fernandez, Enrico Gratton, Jered B. Haun
Summary: Fluorescence lifetime-based multiplexing allows simultaneous detection of multiple probes, and the phasor approach provides a simple solution for lifetime analysis. This study demonstrates the ability of phasor analysis to resolve and quantify exogenous fluorescent probes based on lifetime information alone. It also shows that lifetime-based quantitation accuracy can be improved through intensity matching. The results highlight the potential of fluorescence lifetime imaging and phasor analysis as a powerful tool for simultaneous detection of multiple biomarkers.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Ting Meng, Zifei Wang, Ting Yuan, Xiaohong Li, Yunchao Li, Yang Zhang, Louzhen Fan
Summary: This study presents a gram-scale synthesis of red/green/blue solid-state fluorescent carbon quantum rings with high quantum yields, offering a potential alternative to REE-free phosphor-converted white LEDs. These R/G/B-SBF-CQRs-based LEDs emit warm white light with low CCT, high CRI, and high luminous efficiency, comparable to REE-phosphor-based LEDs.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Multidisciplinary Sciences
Zhilun Zhao, Chen Chen, Shixuan Wei, Hanqing Xiong, Fanghao Hu, Yupeng Miao, Tianwei Jin, Wei Min
Summary: Raman-active nanoparticles (Rdots) with ultra-brightness and compact sizes are developed for high-resolution imaging of complex biological networks and immunostaining of specific protein targets.
NATURE COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Xiaobo Zhou, Lingfeng Zhao, Ke Zhang, Chaojie Yang, Shijie Li, Xiaoxia Kang, Guo Li, Qi Wang, Haiwei Ji, Mingmin Wu, Jinxia Liu, Yuling Qin, Li Wu
Summary: This study presented a strategy for designing and fabricating narrow emissive AIEdots with tunable wavelengths by constructing a light-harvesting system with high energy transfer efficiency, resulting in high brightness and narrow emission.
Article
Environmental Sciences
Samran Durrani, Jie Zhang, Ai-Ping Pang, Yichen Gao, Tian-Yu Wang, Haiyan Wang, Fu-Gen Wu, Fengming Lin
Summary: This paper presents a method for ion detection using multicolor N-doped carbon dots (mPD-CDs). The mPD-CDs were easily synthesized and successfully used for multicolor cellular imaging and fluorescent sensing of various ions. They showed great potential for ultrasensitive sensing of multiple metal ions in the environment and biological systems.
ENVIRONMENTAL RESEARCH
(2022)
Article
Chemistry, Multidisciplinary
Wei Li Ang, Jiri Sturala, Nikolas Antonatos, Zdenek Sofer, Alessandra Bonanni
Summary: Chemically modified germanenes with different surface ligands show strong influence on intrinsic fluorescence and affect bio-conjugation ability and bio-recognition efficiency towards analyte detection. Methylated germanene material demonstrates improved calibration sensitivity, reproducibility, and linearity for real sample analysis in optical bioassays.
Article
Materials Science, Biomaterials
Jie Dai, Zixing Xu, Jinhua Xu, Huoyue Lin, Xuan Yang, Jun Wang, Gang Ruan
Summary: The challenge of biological delivery in biotechnology is due to the need to overcome multiple barriers. SDot nanoparticles were designed with a hydrophobic bio-interface to enhance interactions with lipid membranes. In experiments, PTX@SDots-RGD displayed excellent intracellular targeting ability to microtubules in U87MG cells, suggesting the potential of SDots-RGD for bio-delivery.
JOURNAL OF MATERIALS CHEMISTRY B
(2023)
Article
Chemistry, Multidisciplinary
Zheng Dang, Yong Guan, Zhao Wu, Xia-Yu Tao, Ying Xiong, Hao-Bo Bai, Chang-Sheng Shao, Gang Liu, Qing Huang, Li-Jiao Tian, Yang-Chao Tian
Summary: This study demonstrates the controlled biosynthesis of iron sulfide nanoparticles with excellent performance in cancer therapy. Tuning the synthesis rate and yield of FeS NPs can be achieved by altering the initial iron precursor dosage. The FeS NPs exhibit good cancer therapy performance and achieve excellent in vivo therapeutic effects.
Article
Chemistry, Multidisciplinary
Niall M. C. Mulkerns, William H. Hoffmann, Javier Ramos-Soriano, Noelia de la Cruz, Teodoro Garcia-Millan, Robert L. Harniman, Ian D. Lindsay, Annela M. Seddon, M. Carmen Galan, Henkjan Gersen
Summary: A practical method based on measuring the refractive index of nanoparticles in suspension is proposed for determining the ratio of functionalisation layer volume to particle volume. The method is successfully applied to different nanoparticles and shows the ability to detect differences in surface functionalisation or composition of nanosized particles. This non-destructive and rapid method is well-suited for industrial particle characterisation and biological applications.
Article
Chemistry, Multidisciplinary
Alexander M. Saeboe, Alexey Y. Nikiforov, Reyhaneh Toufanian, Joshua C. Kays, Margaret Chern, J. Paolo Casas, Keyi Han, Andrei Piryatinski, Dennis Jones, Allison M. Dennis
Summary: This report showcases the reddest emitting indium phosphide quantum dots to date, demonstrating tunable near-infrared photoluminescence and PL multiplexing in the first optical tissue window while avoiding toxic constituents. By utilizing an inverted QD heterostructure, the synthesis overcomes the growth bottleneck and extends the emission peak of the nanoparticles into the deeper optical tissue window.
Article
Spectroscopy
Xiaoping Chen, Jianwei Lin, Yafeng Zhuang, Siqi Huang, Jinghua Chen, Zhizhong Han
Summary: A new ratiometric fluorescence sensor is developed for the selective detection of chlorotetracycline (CTC) using dual-mode fluorescence method, demonstrating good selectivity and sensitivity.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Analytical
Zihui Liang, Junyi Zhao, Peilin Wang, Yixin Nie, Shuping Xu, Qiang Ma
Summary: In this study, a polarization-resolved ECL sensor based on the surface plasmon coupling effect was constructed for sensitive detection of miRNA-155, which is related to triple-negative breast cancer. The sensing system utilized a gold nanorod vertical array as a surface-enhanced structure, improving the detection sensitivity of the ECL signal.
ANALYTICAL CHEMISTRY
(2022)
Review
Chemistry, Multidisciplinary
Yu Cheng, Si Da Ling, Yuhao Geng, Yundong Wang, Jianhong Xu
Summary: Microfluidic technology offers a controllable and efficient method for producing high-quality quantum dots, which can be used for bio-sensing and bio-imaging applications. It also serves as an effective platform to understand the synthetic mechanism and optimize reaction parameters for quantum dot production.
NANOSCALE ADVANCES
(2021)
Review
Engineering, Environmental
Jixi Zhang, Jiahui Jin, Jianqin Wan, Shaohua Jiang, Yongzhong Wu, Wufeng Wang, Xiao Gong, Hangxiang Wang
Summary: Research on QDs/hydrogel composites is progressing rapidly with wide applications in health, energy, and environment. Synthetic strategies are classified based on preparative sequence, and the latest applications in sensing, particularly fluorescence sensing, are summarized.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Chemistry, Inorganic & Nuclear
Chuqiao Wu, Wenjie Sun, Qianming Wang
Summary: In this study, various sulfur-derived nanomaterials were prepared using different sulfur sources, with poly(ethylene glycol) playing an important role in the assembly process and the definition of sulfur dots being inaccurate. The photophysical properties of different sulfur-derived nanomaterials vary, with NSO-QDs demonstrating high selectivity and sensitivity in the detection of Ni2+.
INORGANIC CHEMISTRY
(2022)