期刊
JOURNAL OF BIOMEDICAL OPTICS
卷 17, 期 7, 页码 -出版社
SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS
DOI: 10.1117/1.JBO.17.7.075002
关键词
optical stimulation; cochlear implant; Monte Carlo; simulations; laser
资金
- Australian Research Council [LP120100264]
- Australian Research Council [LP120100264] Funding Source: Australian Research Council
A Monte Carlo model has been developed to simulate light transport and absorption in neural tissue during infrared neural stimulation (INS). A range of fiber core sizes and numerical apertures are compared illustrating the advantages of using simulations when designing a light delivery system. A range of wavelengths, commonly used for INS, are also compared for stimulation of nerves in the cochlea, in terms of both the energy absorbed and the change in temperature due to a laser pulse. Modeling suggests that a fiber with core diameter of 200 mu m and NA = 0.22 is optimal for optical stimulation in the geometry used and that temperature rises in the spiral ganglion neurons are as low as 0.1 degrees C. The results show a need for more careful experimentation to allow different proposed mechanisms of INS to be distinguished. (C) 2012 Society of Photo-Optical Instrumentation Engineers (SPIE). [DOI: 10.1117/1.JBO.17.7.075002]
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