期刊
JOURNAL OF BIOMEDICAL OPTICS
卷 15, 期 5, 页码 -出版社
SPIE-SOC PHOTOPTICAL INSTRUMENTATION ENGINEERS
DOI: 10.1117/1.3494565
关键词
absolute blood velocity; Radon transform; flow; perfusion
资金
- National Institutes of Health [RO1 EY017577]
We present a new method for the quantitative estimation of blood flow velocity, based on the use of the Radon transform. The specific application is for measurement of blood flow velocity in the retina. Our modified fundus camera uses illumination from a green LED and captures imagery with a high-speed CCD camera. The basic theory is presented, and typical results are shown for an in vitro flow model using blood in a capillary tube. Subsequently, representative results are shown for representative fundus imagery. This approach provides absolute velocity and flow direction along the vessel center-line or any lateral displacement therefrom. We also provide an error analysis allowing estimation of confidence intervals for the estimated velocity. (C) 2010 Society of Photo-Optical Instrumentation Engineers. [DOI: 10.1117/1.3494565]
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