期刊
JOURNAL OF BIOMEDICAL OPTICS
卷 14, 期 2, 页码 -出版社
SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS
DOI: 10.1117/1.3103778
关键词
thermoacoustic tomography; photoacoustic tomography; negative acoustic lens; tangential resolution
资金
- National Institutes of Health [R01 EB000712, R01 NS046214]
- NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [R01EB000712] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [R01NS046214] Funding Source: NIH RePORTER
We developed a novel concept of using a negative acoustic lens to increase the acceptance angle of an unfocused large-area ultrasonic transducer (detector), leading to more than twofold improvement of the tangential resolution in both thermoacoustic and photoacoustic tomography. In both thermoacoustic and photoacoustic tomography, for a given transducer bandwidth, the aperture size of the detector affects the tangential resolution greatly when the object of interest is near the detector surface. We were able to overcome such tangential resolution deterioration by attaching an acoustic concave lens, made of acrylic in front of the flat detector surface. We then quantified the tangential resolution improvement using phantom images. We also showed that the use of the negative lens preserves the shape of an object after the image is reconstructed. (C) 2009 Society of Photo-Optical Instrumentation Engineers. [DOI: 10.1117/1.3103778]
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