Article
Biophysics
Lanting Qian, Sharmila Durairaj, Scott Prins, Aicheng Chen
Summary: The rapid growth of the pharmaceutical industry due to increasing human population has led to the need for advanced nanomaterial-based electrochemical sensors and biosensors for monitoring pharmaceutical pollutants. This review article surveys state-of-the-art sensors for detecting significant pharmaceutical compounds and highlights strategies for developing high-performance sensors tailored toward specific pharmaceuticals.
BIOSENSORS & BIOELECTRONICS
(2021)
Review
Biotechnology & Applied Microbiology
Tahir Raza, Lijun Qu, Waquar Ahmed Khokhar, Boakye Andrews, Afzal Ali, Mingwei Tian
Summary: Conductive nanostructured materials are currently being used in the fabrication of modern chemical and biological sensors, with carbon, metals, and conductive polymers playing key roles. The combination of conductive polymer nanocomposites with carbon and metal nanoparticles is highlighted as a way to enhance sensor performance, with future challenges and opportunities in this field also discussed.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Review
Chemistry, Analytical
Masoud Negahdary, Lucio Angnes
Summary: Recent research in electrochemical biosensors equipped with peptides and nanomaterials has been categorized, reviewed, and critically analyzed. These innovative biosensors have the potential to revolutionize biomedical diagnostics, with saving lives, time, and money being the main benefits. These biosensors have been divided into four main sections and evaluated based on their types and applications.
Review
Nanoscience & Nanotechnology
Xiaohua Ma, Yuanqiang Hao, Lin Liu
Summary: Exosomes, small membrane-bound vesicles secreted by cells, have been considered as emerging and noninvasive biomarkers for cancer diagnosis. Integration of nanomaterials with various techniques significantly improves the analytical performances of exosome biosensors.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2021)
Review
Chemistry, Analytical
Hemraj Mahipati Yadav, Jong-Deok Park, Hyeong-Cheol Kang, Jae-Joon Lee
Summary: Functional nanomaterials have attracted attention for their controllable morphology, stability, biocompatibility, and unique properties, particularly in the healthcare system. These nanomaterials, especially in cholesterol biosensors, have shown significant progress in clinical diagnosis of cardiovascular diseases. Various nanomaterials have been used in the electrochemical sensing of cholesterol, indicating promising pathways for cholesterol detection in the future.
Review
Nanoscience & Nanotechnology
Krishna Thapa, Wenyan Liu, Risheng Wang
Summary: DNA-based electrochemical biosensors have attracted scientific and clinical interests due to their specificity and fast response time. Strategies for DNA probe immobilization and signal amplification play a critical role in achieving high detection sensitivity. Advancements in nanotechnology and biochemistry show promise in the development of portable sensing devices for clinical testing.
WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY
(2022)
Article
Environmental Sciences
M. Ramya, P. Senthil Kumar, Gayathri Rangasamy, V. Uma Shankar, G. Rajesh, K. Nirmala, A. Saravanan, Alagumalai Krishnapandi
Summary: Industrialization and globalization have led to the release of large quantities of toxic chemicals into the environment, highlighting the importance of developing sensitive, reliable, and cost-effective environmental pollutant sensor platforms. Progress has been made in recent years in expanding electrochemical sensors and biosensors using nanomaterials, with a focus on rapidly detecting emerging biomarkers in various applications. Numerous trends in the growth of nanotechnology-based electrochemical sensor platforms have been identified, showcasing the integration strategies, applications, specific properties, and future projections of nanostructured materials for advanced sensor platforms.
Article
Biochemical Research Methods
Zondi Nate, Atal A. S. Gill, Ruchika Chauhan, Rajshekhar Karpoormath
Summary: Malaria remains a significant disease in sub-Saharan Africa and South-East Asia, despite intervention efforts by the WHO. The lack of rapid diagnostic tools is a major challenge, highlighting the need for the development of cost-effective and portable analytical methods. This review explores the role of malaria biomarkers and discusses recent advancements in nanomaterial-based biosensors for malaria diagnosis.
ANALYTICAL BIOCHEMISTRY
(2022)
Review
Chemistry, Analytical
Robert D. Crapnell, Craig E. Banks
Summary: Research into electrochemical biosensors is vital for the development of reliable and sensitive detection platforms for key environmental and medical biomarkers. Utilization of micro- and nano-dimensional materials has significantly enhanced the performance of biosensors, with an emphasis on combining different materials to exploit their unique properties. Continued exploration into micro-nano materials and understanding their individual and synergistic properties will drive further advancements in biosensing technologies, providing solutions for global sensing requirements.
Review
Chemistry, Analytical
Mohd Syafiq Awang, Yazmin Bustami, Hairul Hisham Hamzah, Nor Syafirah Zambry, Mohamad Ahmad Najib, Muhammad Fazli Khalid, Ismail Aziah, Asrulnizam Abd Manaf
Summary: Large-scale food-borne outbreaks caused by Salmonella are rare nowadays thanks to advanced medical systems, but localized outbreaks still pose a threat to public health. Various detection methods, such as immunological, molecular, mass spectrometry, spectroscopy, optical phenotyping, and biosensors, are available for Salmonella detection. Electrochemical biosensors, especially those utilizing aptamers and nanomaterials, are gaining interest due to sensitivity, speed, and portability.
Review
Food Science & Technology
Zanlin Chen, Miaojia Xie, Fengguang Zhao, Shuangyan Han
Summary: The increasing heavy metal pollution requires the development of a sensitive, simple, and reproducible detection method. Aptamers, as new artificial probes, have gained attention for their high sensitivity, easy acquisition, wide target range, and wide use in detecting harmful substances. The use of nanomaterials in aptamer-based electrochemical biosensors significantly improves the detection sensitivity.
Review
Chemistry, Analytical
Zina Fredj, Mohamad Sawan
Summary: Catecholamines are crucial neurotransmitters in the central nervous system and play key roles in neurological disorders. Optical and electrochemical biosensors have been widely adopted for the real-time monitoring of catecholamine neurotransmitters and their development has been greatly accelerated in the last decade. This review provides a comprehensive overview on the recent advances and main challenges in catecholamines biosensors, with emphasis on electrochemical biosensors and the unique characteristics brought by nanotechnology. It also summarizes the therapeutic use of nanomaterials for catecholamine analysis and future development trends based on specific biosensors' performance metrics.
Review
Electrochemistry
Miroslav Pohanka
Summary: Biosensors are important analytical devices, and aptamers as a new biorecognition element play a significant role in them. Aptamers are short sequences of DNA, RNA, and peptides with high affinity similar to antibodies. Aptasensors with immobilized aptamers serve as an alternative to biosensors based on antibodies and other bioreceptor molecules.
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE
(2022)
Review
Engineering, Electrical & Electronic
Seyyed Mojtaba Mousavi, Gity Behbudi, Seyyed Alireza Hashemi, Aziz Babapoor, Wei-Hung Chiang, Seeram Ramakrishna, Mohammed Muzibur Rahman, Chin Wei Lai, Ahmad Gholami, Navid Omidifar, Khadije Yousefi
Summary: The study investigated the applications of advanced nanomaterials such as graphene oxide (GO), reduced graphene oxide (rGO), and graphene quantum dots (GQDs) towards treating human papillomaviruses (HPVs). Efforts have been made to develop high-performance biosensors and electrochemical detection systems for accurate HPV detection. The review discussed the different types and complications of HPVs and highlighted the importance of boosting the human immune system to effectively treat this dangerous virus.
JOURNAL OF SENSORS
(2021)
Article
Chemistry, Analytical
Nutcha Larpant, Pramod K. Kalambate, Tautgirdas Ruzgas, Wanida Laiwattanapaisal
Summary: This study proposed a strategy of using paper-based competitive immunochromatography and a near field communication tag for wireless cotinine determination. The research found that this new method can accurately detect nicotine levels in urine and differentiate between smokers and non-smokers.
