期刊
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
卷 101B, 期 2, 页码 213-222出版社
WILEY
DOI: 10.1002/jbm.b.32824
关键词
edge loading; metal-on-metal; hip replacement; microseparation; inclination angle
资金
- Orthopaedic Research UK (ORUK)
- National Institute of Health Research (NIHR)
- Leeds Musculoskeletal Biomedical Research Unit (LMBRU)
- NIHR LMBRU
- WELMEC Wellcome Trust
- Technology Strategy Board
- EPSRC
- BBSRC
- EPSRC [WT088908/z/09/z]
- Engineering and Physical Sciences Research Council [EP/I019103/1, EP/F043872/1, EP/G032483/1, EP/K029592/1, EP/J017620/1] Funding Source: researchfish
- National Institute for Health Research [NF-SI-0611-10096] Funding Source: researchfish
- EPSRC [EP/F043872/1, EP/I019103/1, EP/K029592/1, EP/J017620/1, EP/G032483/1] Funding Source: UKRI
Metal-on-metal (MoM) bearings have shown low-wear rates under standard hip simulator conditions; however, retrieval studies have shown large variations in wear rates and mechanisms. High-wear in vivo has caused catastrophic complications and has been associated with steep cup-inclination angle (rotational malpositioning). However, increasing the cup-inclination angle in vitro has not replicated the increases in wear to the same extent as those observed in retrievals. Clinically relevant wear rates, patterns, and particles were observed in vitro for ceramic-on-ceramic bearings when microseparation (translational malpositioning) conditions were introduced into the gait cycle. In the present study, 28 and 36-mm MoM bearings were investigated under adverse conditions. Increasing the cup angle from 45 degrees to 65 degrees resulted in a significant increase in the wear rate of the 28 mm bearings. However, for the 36 mm bearings, head-rim contact did not occur under the steep cup-angle condition, and the wear rate did not increase. The introduction of microseparation to the gait cycle significantly increased the wear rate of the MoM bearings. Cup angle and head size did not influence the wear rate under microseparation conditions. This study indicated that high-in vivo wear rates were associated with edge loading due to rotational malpositioning such as high-cup-inclination angle and translational malpositioning that could occur due to several surgical factors. Translational malpositioning had a more dominant effect on the wear rate. Preclinical simulation testing should be undertaken with translational and rotational malpositioning conditions as well as standard walking cycle conditions defined by the ISO standard. (c) 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2013.
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