Article
Chemistry, Medicinal
Shiyuan Chang, Xiaoyong Chen, Yifan Chen, Lijun You, Kseniya Hileuskaya
Summary: This study analyzed the structural properties and anti-inflammatory activity of purified fractions derived from UV/H2O2-degraded polysaccharides from Sargassum fusiforme. The results showed that two fractions with different monosaccharide compositions and morphological characteristics were obtained, and PT-0.5 exhibited better anti-inflammatory activity.
Article
Dentistry, Oral Surgery & Medicine
Fadi N. Barrak, Siwei Li, Ali A. Mohammed, Connor Myant, Julian R. Jones
Summary: This study assessed the impact of the dissolution products of S53P4 bioactive glass (BG) on the cellular response to dental implant particles. The results showed that the presence of Ti-6Al-4V implant particles induced significant inflammation in all tested cell types. The S53P4 BG dissolution products suppressed the particle-induced inflammation and potentially influenced macrophage polarization behavior.
JOURNAL OF DENTISTRY
(2022)
Article
Materials Science, Multidisciplinary
Amir Rezvan, Elham Sharifikolouei, Viktor Soprunyuk, Wilfried Schranz, Juraj Todt, Alice Lassnig, Christoph Gammer, Nikolaus August Sifferlinger, Atacan Asci, Ilya Okulov, Sandra Schlogl, Jozef Keckes, Ziba Najmi, Andrea Cochis, Alessandro Calogero Scalia, Lia Rimondini, Baran Sarac, Juergen Eckert
Summary: The application of highly biocompatible advanced materials leads to fewer complications and more successful medical treatments. This study proposes a new type of metallic glass that can be used as an oral implant material, and it explores the processing methods to improve its specific properties. The results show that the processed material has higher thermomechanical stability and better cytocompatibility.
MATERIALS & DESIGN
(2023)
Article
Pharmacology & Pharmacy
Laila Pereira Silva, Eliziaria Cardoso Santos, Bruno Arantes Borges, Marcia Paranho Veloso, Daniela Aparecida Chagas-Paula, Reggiani Vilela Goncalves, Romulo Dias Novaes
Summary: The study demonstrates that TAG-F can effectively reduce the production of inflammatory mediators and promote tissue healing in skin wounds, alleviating swelling and pain.
PHARMACOLOGICAL RESEARCH
(2021)
Article
Multidisciplinary Sciences
Paiboon Jitprasertwong, Munthipha Khamphio, Phornsiri Petsrichuang, Vincent G. H. Eijsink, Wanangkan Poolsri, Chatchai Muanprasat, Kuntalee Rangnoi, Montarop Yamabhai
Summary: The study investigated the anti-inflammatory activity of well-characterized low molecular weight soluble CHOS in human cell lines, demonstrating that CHOS can reduce the production of pro-inflammatory cytokines without affecting cell viability. Vitamin D3-stimulated THP-1 cells were identified as a favorable system for assessing the anti-inflammatory activity of bioactive compounds.
Article
Biotechnology & Applied Microbiology
Nian Liu, Hui Wang, Zeyu Fu, Chuxi Zhang, Wenyu Hui, Jinyang Wu, Yong Zhang, Shilei Zhang
Summary: Studies have shown that quercetin-coating on 3D-printed titanium alloy implants can enhance osseointegration and anti-inflammatory properties. In vitro experiments have demonstrated that the quercetin-coating can improve cell adhesion and osteogenic differentiation, as well as modulate macrophage polarization and the expression of anti-inflammatory genes. In vivo experiments have shown that quercetin-loaded implants can reduce peri-implant inflammation and promote new bone formation and rapid osseointegration.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Spectroscopy
Samannan Bharath, Alphonse Lazer, Yi-Li Lin, Praveen Peter, Jeyabalan Thavasikani
Summary: A novel keggin-type tetra-metalates substituted polyoxometalate was functionalized by 3-(aminopropyl)-imidazole (3-API) supporting a ligand substitution method. The hybrid material 3-API/POMs exhibited excellent photo-catalytic properties for the degradation of azo-dye molecules under visible light illumination. The degradation efficiency of the azo-dye reached 89.9% in the presence of 3-API/POMs.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Biochemistry & Molecular Biology
Yisett Gonzalez, Randy Mojica-Flores, Dilan Moreno-Labrador, Luis Cubilla-Rios, K. S. Jagannatha Rao, Patricia L. Fernandez, Oleg V. Larionov, Johant Lakey-Beitia
Summary: In this study, new curcumin derivatives with improved anti-inflammatory activity were synthesized and evaluated. Thirteen derivatives were synthesized by Steglich esterification on the phenolic rings of curcumin, and the monofunctionalized compounds showed better bioactivity than the difunctionalized derivatives in inhibiting IL-6 production. Compound 2 exhibited the highest activity and also showed strong activity against PGE(2) synthesis. The structure-activity relationship analysis revealed that the presence of a free hydroxyl group or aromatic ligands on the curcumin ring, along with the absence of a linker moiety, contributed to the increased activity of this series of compounds.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Physical
Peng Du, Bohua Li, Jie Chen, Kun Li, Guoqiang Xie
Summary: A non-toxic and biocompatible Ti-Zr-Si metallic glass was successfully prepared through mechanical alloying and spark plasma sintering techniques, showing a porosity of 16%, a compression strength of 357 MPa, and a Young's modulus of 48 GPa, similar to human bone. This research provides new possibilities for the use of Ti-Zr-Si metallic glass in medical equipment.
JOURNAL OF ALLOYS AND COMPOUNDS
(2023)
Article
Environmental Sciences
Rajasree Shanmuganathan, Quynh Hoang Le, Sandhanasamy Devanesan, Shaban R. M. Sayed, V. Devi Rajeswari, Xinghui Liu, G. K. Jhanani
Summary: In ancient times, herbal plants were highly valued for their medicinal uses, with mint being commonly used in traditional medicine. This study focuses on using mint leaf extract to synthesize safe calcium oxide (CaO) nanoparticles and evaluating their potential therapeutic applications. Various techniques such as UV-visible spectrophotometry, FTIR, SEM, DLS, and XRD were employed to examine the characteristics of the extracted CaO nanoparticles. Protein denaturation and nitric oxide scavenging assays, as well as MTT assays, were conducted to assess the therapeutic properties of the mint leaf mediated CaO nanoparticles. Additionally, the ability of these nanoparticles to act as photocatalytic agents was examined by studying their degradation of commonly used azo dyes in textile industries.
ENVIRONMENTAL RESEARCH
(2023)
Article
Pharmacology & Pharmacy
Federica Dell'Annunziata, Stefania Cometa, Roberta Della Marca, Francesco Busto, Veronica Folliero, Gianluigi Franci, Massimiliano Galdiero, Elvira De Giglio, Anna De Filippis
Summary: This study evaluated the antimicrobial activity of Arctostaphylos uva-ursi leaf extract against the main causative agent of acne vulgaris, C. acnes. The extract showed inhibitory effects on planktonic C. acnes and disrupted biofilm biomass formation. It did not affect the viability of human keratinocytes and inhibited the secretion of pro-inflammatory cytokines. These findings suggest that Arctostaphylos uva-ursi leaf extract could be a natural alternative for treating acne vulgaris.
Article
Engineering, Mechanical
Wei-Hui Lin, Chong-Min She, Chun-Yu Zhang, Paulo S. Branicio, Zhen - Dong Sha
Summary: The mechanical properties of cellular metallic glasses are influenced by the shape of their cellular structures. Random structures with uniform porosity show higher yield strength and Young's modulus compared to microlattice structures. The chiral structure displays the highest Young's modulus, while stochastic cellular structures exhibit higher energy absorption capacity.
INTERNATIONAL JOURNAL OF PLASTICITY
(2022)
Review
Plant Sciences
Marcello Nicoletti
Summary: The therapeutic story of European mistletoe has had ups and downs. In ancient times, it was considered a panacea, but recent concerns about its toxicity led to doubts about its medicinal value. However, its selective action on tumor cells has brought back medical interest in mistletoe.
Article
Multidisciplinary Sciences
Zahra Nabizadeh, Mahmoud Nasrollahzadeh, Ali Akbar Shabani, Majid Mirmohammadkhani, Davood Nasrabadi
Summary: Cartilage lesions, especially osteoarthritis, can cause pain and disability. This study aimed to develop chitosan-based nanoparticles for delivering fisetin, a compound with anti-inflammatory effects. The results showed that these nanoparticles were able to inhibit inflammatory responses and had good compatibility with cells and blood.
SCIENTIFIC REPORTS
(2023)
Review
Biochemistry & Molecular Biology
Monica Bucciantini, Manuela Leri, Pamela Nardiello, Fiorella Casamenti, Massimo Stefani
Summary: Oxidative stress and inflammation are major causes of chronic diseases, leading to the search for new active substances without side effects. Plant-derived compounds offer potential as anti-inflammatory and antioxidant molecules, with natural products being structurally optimized by evolution for specific biological functions. Extensive studies have shown the therapeutic effects of polyphenols from extra virgin olive oil against various chronic diseases, highlighting their role in inhibiting molecular signaling pathways activated by oxidative stress.
Article
Chemistry, Inorganic & Nuclear
Houjian Zhou, Hao Ding, Zhipeng Yu, Tongtong Yu, Kun Zhai, Bochong Wang, Congpu Mu, Fusheng Wen, Jianyong Xiang, Tianyu Xue, Lin Wang, Zhongyuan Liu, Young Sun, Yongjun Tian
Summary: The research on multiferroic materials by modifying their properties through pressure has expanded the multiferroic phase region to higher temperatures and created a temperature-pressure phase diagram.
INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Physical
Baozhong Li, Kun Luo, Yanfeng Ge, Yang Zhang, Ke Tong, Bing Liu, Guochun Yang, Zhisheng Zhao, Bo Xu, Yongjun Tian
Summary: Finding a material with high hardness and toughness is a crucial research topic. This study introduces a new superior mechanical material called Gradia, composed of diamond and graphite nanodomains interlocked via coherent interfaces. Gradia exhibits sequential structural transitions under strain, leading to outstanding toughness. Furthermore, it has the potential to be a superhard material with estimated Vickers hardness exceeding 40 GPa. This work could be exemplary in exploring excellent mechanical materials through the modulation of carbon building block linking styles.
Article
Chemistry, Physical
Linyan Wang, Xudong Wei, Xiaokuan Hao, Xiaoxu Song, Guochun Yang, Cheng Lu, Yuanzheng Chen, Lin Wang, Guoying Gao, Yongjun Tian
Summary: We conducted an extensive study on different B-P stoichiometries under pressure using a particle swarm optimization method and first-principles calculations. BP and B6P were found to be thermodynamically stable at 1 atm, while other stoichiometries were metastable. Under pressure, BP and B6P remained stable up to 80 GPa, while other stoichiometries became unstable at lower pressures. We predicted a new Cmca B6P structure with the lowest energy and higher shear strain than the R (3) over barm structure. Additionally, we found that the predicted Pm B8P is a magnetic semiconductor with a magnetic moment of 1 mu(B). All these boron-rich phosphides are hard materials. These results enrich the B-P phase diagram and promote extensive research on their excellent properties.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2023)
Article
Chemistry, Physical
Zihe Li, Yujia Wang, Mengdong Ma, Huachun Ma, Wentao Hu, Xiang Zhang, Zewen Zhuge, Shuangshuang Zhang, Kun Luo, Yufei Gao, Lei Sun, Alexander V. Soldatov, Yingju Wu, Bing Liu, Baozhong Li, Pan Ying, Yang Zhang, Bo Xu, Julong He, Dongli Yu, Zhongyuan Liu, Zhisheng Zhao, Yuanzheng Yue, Yongjun Tian, Xiaoyan Li
Summary: By controlling the transformation of amorphous carbon into diamond, researchers synthesized an in-situ composite consisting of ultrafine nanodiamond uniformly dispersed in disordered multilayer graphene with incoherent interfaces. This composite exhibits high hardness, high strength, and high electrical conductivity, surpassing traditional ceramics and C/C composites in comprehensive properties.
Article
Engineering, Electrical & Electronic
Ming Tang, Junwei Huang, Feng Qin, Kun Zhai, Toshiya Ideue, Zeya Li, Fanhao Meng, Anmin Nie, Linglu Wu, Xiangyu Bi, Caorong Zhang, Ling Zhou, Peng Chen, Caiyu Qiu, Peizhe Tang, Haijun Zhang, Xiangang Wan, Lin Wang, Zhongyuan Liu, Yongjun Tian, Yoshihiro Iwasa, Hongtao Yuan
Summary: Controlling the magnetic anisotropy of ferromagnetic materials is crucial for the development of magnetic switching devices and spintronic applications. This study demonstrates the gate-tunable modulation of magnetic anisotropy in the van der Waals ferromagnet Fe5GeTe2, allowing for continuous rotation of the magnetic easy axis from an out-of-plane to an in-plane orientation. The results show that the modulation of anisotropy can be achieved via a spin-flop pathway and the range of modulation is significant, from 2.11 to -0.38 MJ m(-3). Additionally, temperature can also be used to tune the anisotropy.
NATURE ELECTRONICS
(2023)
Article
Nanoscience & Nanotechnology
Binhao Wang, Haidong Zhao, Bin Zhang, Dan Wang, Aihua Song, Chen Chen, Fengrong Yu, Wentao Hu, Dongli Yu, Bo Xu, Yongjun Tian
Summary: The carrier concentration of n-type PbTe can be optimized by doping indium and aluminum, which leads to enhanced thermoelectric performance.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Materials Science, Multidisciplinary
Jingpeng Hou, Keliang Qiu, Fengshi Li, Zhenyu Yang, Yonghai Yue, Yongjun Tian, Zhongchang Wang, Lin Guo
Summary: Twin boundary (TB) is a special and fundamental internal interface that alters the mechanical and physical properties of materials. The deformation mechanism of TB and its effect on material strength and plasticity are still under debate. This study discovered that the pseudoelastic strain of a TB can recover with decomposition and escape of pile-up dislocations, which opens up new possibilities for optimizing material properties by manipulating twin boundaries at the nanoscale.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2023)
Article
Chemistry, Physical
Xiao-Ji Weng, Jie Bai, Jingyu Hou, Yi Zhu, Li Wang, Penghui Li, Anmin Nie, Bo Xu, Xiang-Feng Zhou, Yongjun Tian
Summary: In this study, techniques such as scanning tunneling microscopy, X-ray photoelectron spectroscopy, angle-resolved photoemission spectroscopy, and aberration-corrected scanning transmission electron microscopy were used to validate the crystal structure of copper-rich boride Cu8B14 formed on the single crystal Cu (111) surface after depositing boron. First-principles calculations with defective surface models further showed that boron atoms tend to react with copper atoms near terrace edges or defects, resulting in the formation of intermediate structures and the eventual stable Cu-B monolayer through large-scale surface reconstruction.
Article
Physics, Applied
Yanfeng Ge, Kun Luo, Yong Liu, Guochun Yang, Pan Ying, Yingju Wu, Ke Tong, Bing Liu, Baozhong Li, Guoying Gao, Xiang-Feng Zhou, Zhisheng Zhao, Bo Xu, Yongjun Tian
Summary: The discovery of graphite-diamond hybrid materials (Gradia) has opened up a new direction in carbon allotropes research. In this study, Gradia-HZ, composed of interfaced graphite and hexagonal diamond parts, exhibited distinct electronic and mechanical properties. By modulating the graphite width, Gradia-HZ demonstrated unexpected topological nodal-line semimetal, semiconductor, and normal metal characteristics, along with a distinctive Quasi-1D electronic transport capability based on first-principles calculations. The discovery of unique physical properties in Gradia-HZ, such as high-conductivity metals, semiconductors with variable bandgap, and topological semimetals, will inspire further research and promote the development and application of graphite-diamond hybrid materials.
APPLIED PHYSICS REVIEWS
(2023)
Article
Materials Science, Ceramics
Chen Chen, Bin-Hao Wang, Hai-Dong Zhao, Bin Zhang, Dan Wang, Tao Shen, Peng-Hui Li, Song Zhao, Dong-Li Yu, Yong-Jun Tian, Bo Xu
Summary: In this study, SnSe bulks with a unique microstructure of tightly-bound quasi-equiaxed grains were prepared via a sequential procedure. The produced samples exhibited excellent mechanical properties, including high Vickers hardness, compressive strength, and bending strength. Furthermore, the microstructures did not negatively affect the thermoelectric performance. This work demonstrates an effective procedure to prepare microstructure-engineered SnSe materials and provides insights for enhancing the properties of other layer-structured thermoelectric materials.
JOURNAL OF ADVANCED CERAMICS
(2023)
Article
Materials Science, Multidisciplinary
S. Rahman, Linyan Wang, H. Saqib, D. Errandonea, Li Yang, Yongsheng Zhao, Yukai Zhuang, Guoying Gao, Lin Wang, Yongjun Tian
Summary: The application of high pressure accelerates the understanding of structure and exotic electronic states in transition metal dichalcogenides, leading to the discovery of intriguing phenomena. HfS2 exhibits tunable electronic properties under pressure, with a gradual narrowing of band-gap below 40 GPa, pressure-induced metallization above 40 GPa, and superconductivity starting around 115 GPa. The high Tc superconductivity induced by pressure is closely related to structural reconstructions and changes in electronic states near the Fermi surface.
MATERIALS TODAY PHYSICS
(2023)
Article
Materials Science, Multidisciplinary
Xudong Wei, Xiaokuan Hao, Aitor Bergara, Eva Zurek, Xiaowei Liang, Linyan Wang, Xiaoxu Song, Peifang Li, Lin Wang, Guoying Gao, Yongjun Tian
Summary: Using an advanced crystal structure search method combined with first-principles calculations, researchers predicted a series of ternary hydrides AXH6 (MgPH6, MgAsH6, CaSbH6, CaSnH6, NaSbH6, and ScSiH6) with the A15-type structure to be stable at around one million atmospheres. These ternary hydrides are estimated to be superconductors and provide guidance for designing high Tc ternary hydrides.
MATERIALS TODAY PHYSICS
(2023)
Article
Nanoscience & Nanotechnology
Binhao Wang, Haidong Zhao, Bin Zhang, Dan Wang, Aihua Song, Chen Chen, Fengrong Yu, Wentao Hu, Dongli Yu, Bo Xu, Yongjun Tian
Summary: The n-type indium and aluminum codoped PbTe material was prepared using high-pressure synthesis and spark plasma sintering. The Al doping provided a nearly constant carrier concentration with varying temperatures, while In doping trapped electrons at low temperatures and released them at high temperatures, thus optimizing the carrier concentration over a broad temperature range. As a result, both electrical transport properties and thermal conductivity were optimized, leading to a significantly enhanced thermoelectric performance in InxAl0.02Pb0.98Te. The optimal In0.008Al0.02Pb0.98Te showed a peak ZT of 1.3 and an average ZT of 1, with a decent conversion efficiency of 14%.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Letter
Chemistry, Physical
Linyan Wang, Xudong Wei, Xiaokuan Hao, Xiaoxu Song, Guochun Yang, Cheng Lu, Yuanzheng Chen, Lin Wang, Guoying Gao, Yongjun Tian
Summary: In this study, a comprehensive investigation on different B-P stoichiometries under pressure was conducted by combining a particle swarm optimization method with first-principles calculations. The research revealed that BP and B6P are thermodynamically stable at 1 atm, while others are metastable. Under pressure, BP and B6P remain stable up to 80 GPa, whereas other stoichiometries become unstable at lower pressures. New structures of B6P and B8P were predicted, showing higher shear strain and magnetic properties, respectively. These findings not only enrich the B-P phase diagram, but also promote further exploration of their exceptional properties.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2023)
Article
Materials Science, Ceramics
Chen Junyun, Sun Lei, Jin Tianye, Luo Kun, Zhao Zhisheng, Tian Yongjun
Summary: By adding layered BN at the intersection of cBN grains, a tough Lt-cBN material with high fracture toughness and excellent cutting performance has been developed.
JOURNAL OF INORGANIC MATERIALS
(2022)
