Article
Chemistry, Physical
Xian Wei, Sujie Ma, Jiajia Meng, Hong Qing, Qing Zhao
Summary: Magnesium (Mg) and its alloys have excellent biodegradable properties and biocompatibility, making them attractive materials for orthopedic applications. The Mg-Sn-Ge ternary Mg alloys, with alloying elements naturally present in humans, were developed and investigated for their mechanical properties, degradation behavior, cytocompatibility, and hemocompatibility. Increasing the Ge content significantly improved the hardness and elastic modulus of Mg-2Sn-xGe alloys. The Mg-2Sn-3Ge alloy displayed outstanding biodegradability, and the degradation products weakened at higher Ge levels. The Mg-2Sn-xGe alloys exhibited favorable biocompatibility and hemocompatibility, except for the Mg-2Sn-2Ge alloy.(c) 2023 Published by Elsevier B.V.
JOURNAL OF ALLOYS AND COMPOUNDS
(2023)
Article
Engineering, Biomedical
Julia Gao, Yingchao Su, Yi-Xian Qin
Summary: This study compared the in vitro and in vivo degradation and biocompatibility behaviors of magnesium alloys with calcium phosphate coatings, showing that the CaP coating significantly improved biodegradation behavior and biocompatibility of the Mg alloy. In vitro tests were found to be a quick screening tool for biodegradation rate, with the in vivo degradation rate being slower than in vitro immersion degradation rate.
BIOACTIVE MATERIALS
(2021)
Article
Biophysics
Jingyao Li, Jian Li, Nian He, Qingyun Fu, Mingcheng Feng, Qingyang Li, Qiong Wang, Xiangning Liu, Shu Xiao, Weihong Jin, Zhentao Yu, Paul K. Chu
Summary: Zinc-incorporated calcium phosphate coatings effectively reduce corrosion of Mg alloys and exhibit good biocompatibility and self-repair capability.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Engineering, Biomedical
Diana C. Martinez, Anna Dobkowska, Romy Marek, Hanna Cwieka, Jakub Jaroszewicz, Tomasz P. Plocinski, Crtomir Donik, Heike Helmholz, Berengere Luthringer-Feyerabend, Berit Zeller-Plumhoff, Regine Willumeit-Roemer, Wojciech Swieszkowski
Summary: This study investigated the degradation of an Mg-0.45Zn-0.45Ca (ZX00) screw in vitro and in vivo. The results showed that the ZX00 alloy promoted bone healing and the formation of new bone. Despite the correlation with the production procedure, the ZX00 alloy was still suitable for temporary bone implants.
BIOACTIVE MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Qiuxia Zheng, Zongbin Sun, Zhanhui Wang, Tinghe Duan, Kai Xu, Mengmeng Cai, Bi Wang
Summary: With the popularization of laparoscopic cholecystectomy, ligation clips have been commonly used for ligating the cystic duct and cystic artery. However, non-degradable clips remain in the body long-term, which significantly increases the risk of the clip becoming detached. Magnesium alloys with MAO/PA composite coatings exhibit better corrosion resistance and good biocompatibility, making them a promising choice for medical implants.
Article
Engineering, Environmental
Pingli Jiang, Ruiqing Hou, Tao Chen, Lingchuang Bai, Jingan Li, Shijie Zhu, Liguo Wang, Regine Willumeit-Roemer, Shaokang Guan
Summary: Novel calcium carbonate (CaCO3) coatings were prepared via the hydrothermal method and optimized with the addition of glutamate acid (Glu) or dopamine (DOPA) to improve the degradation and biological performance of MgZnCa alloy.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Engineering, Biomedical
Dongdong Zhang, Mei Li, Ru Xu, Juning Xie, Yu Zhang, Shi Qian, Yuqin Qiao, Feng Peng, Xuanyong Liu
Summary: Magnesium (Mg)-based alloys have shown promise as implants for orthopedics, but improving their corrosion resistance and biofunctions has remained a challenge. In this study, three transition metal-containing layered double hydroxides (LDHs) were prepared on Mg alloy, and their properties were compared. LDH-Mn exhibited the best corrosion resistance, LDH-Fe showed good cytocompatibility and antibacterial properties, and LDH-Co had high cytotoxicity. An optimized bilayer LDH coating enriched with Fe and Mn (LDH-MnFe) was designed, providing excellent anti-corrosion properties and multiple biofunctions (antibacterial, antitumor, and osteogenesis).
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Zhirou Zhang, Qinghuan Huo, Yuxiu Zhang, Yang He, Hiromi Nagaumi, Xuyue Yang
Summary: The individual effects of Y and Nd elements on the precipitate-free zone (PFZ) development and the dislocation creep mechanism of a Mg-4Y-3.5Nd alloy were investigated. Different treatments were applied to the samples, and the creep process was analyzed. The addition of Y and Nd elements diversified the slip types and affected the widening rate of PFZs in the alloy.
MATERIALS CHARACTERIZATION
(2023)
Article
Materials Science, Multidisciplinary
Weijie Weng, Arne Biesiekierski, Jixing Lin, Sertan Ozan, Yuncang Li, Cuie Wen
Summary: This study investigated the newly designed beta-type Ti-Nb-Zr-Mo (TNZM) alloys for orthopedic applications, and found that TNZM1, TNZM2, and TNZM3 exhibited higher elastic admissible strain, high hardness, good ductility, and cytocompatibility.
APPLIED MATERIALS TODAY
(2021)
Article
Materials Science, Biomaterials
Philipp Brunner, Florian Brumbauer, Eva-Maria Steyskal, Oliver Renk, Annelie-Martina Weinberg, Hartmuth Schroettner, Roland Wuerschum
Summary: The study reveals that high-pressure torsion significantly reduces the corrosion resistance of Mg-0.45wt%Zn-0.45wt%Ca alloy, resulting in the formation of larger open-volume structures during corrosion, possibly related to hydrogen.
BIOMATERIALS SCIENCE
(2021)
Article
Engineering, Biomedical
Nadia Aboutalebianaraki, Peter Zeblisky, M. D. Sarker, Aadithya Jeyaranjan, Tamil S. Sakthivel, Yifei Fu, John Lucchi, Matthieu Baudelet, Sudipta Seal, Thomas J. Kean, Mehdi Razavi
Summary: This study developed a novel biodegradable magnesium alloy with scandium and strontium as alloying elements. The alloy exhibited controlled corrosion, enhanced mechanical properties, improved antibacterial activity, and increased osteogenic activity. The heat-treated Mg-Sc-Sr alloy at 400 degrees C displayed optimal characteristics.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
(2023)
Article
Crystallography
Weiyan Jiang, Wenzhou Yu
Summary: The application of biodegradable alloys in orthopedic implants has gained significant attention. The research investigated the performance of a Mg-1Zn-xSn alloy and found that it exhibited enhanced mechanical properties and in vitro degradation performance compared to the Mg-1Zn alloy. The Mg-1Zn-1.0Sn alloy showed particularly promising results, with extremely low corrosion rate and hydrogen release, as well as zero cytotoxicity grade.
Article
Materials Science, Multidisciplinary
Sandeep Kumar Jhamb, Ashish Goyal, Anand Pandey, Mrigesh Navalkishor Verma
Summary: Magnesium alloy is a potential biomaterial for bone implants, but its degradation rate is too fast. This study used alloying treatment technique to slow down the degradation rate and investigated the properties of Mg-Sn alloys with different tin concentrations. The results showed that increasing the tin concentration improves the mechanical properties and reduces the corrosion properties of the alloy.
JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE
(2023)
Article
Chemistry, Physical
Rongfa Zhang, Sheng Zhong, Lilan Zeng, Hongyu Li, Rongfang Zhao, Shufang Zhang, Xinting Duan, Jingsong Huang, Ying Zhao
Summary: The study found that MAO coatings with proper magnesium contents can improve the cytocompatibility of Ti-6Al-4V alloys, while coatings with excessively high magnesium content have poor cytocompatibility.
Article
Engineering, Biomedical
Vasanth C. Shunmugasamy, Marwa AbdelGawad, Muhammad Umar Sohail, Talal Ibrahim, Talha Khan, Thomas Daniel Seers, Bilal Mansoor
Summary: The microstructure of a biodegradable Mg-Zn-RE-Zr alloy was improved by friction stir processing (FSP), resulting in enhanced corrosion resistance and mechanical properties. In vivo evaluation showed promising potential for osseointegration and controlled biodegradability. This study has significant implications for bone fracture management.
BIOACTIVE MATERIALS
(2023)
Article
Engineering, Biomedical
Ren-Guo Guan, Ian Johnson, Tong Cui, Tong Zhao, Zhan-Yong Zhao, Xue Li, Huinan Liu
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
(2012)
Article
Engineering, Biomedical
Maria Emil Iskandar, Arash Aslani, Huinan Liu
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
(2013)
Article
Engineering, Biomedical
Jaclyn Y. Lock, Eric Wyatt, Srigokul Upadhyayula, Andrew Whall, Vicente Nunez, Valentine I. Vullev, Huinan Liu
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
(2014)
Article
Engineering, Biomedical
Meriam Sebaa, Thanh Yen Nguyen, Shan Dhillon, Salvador Garcia, Huinan Liu
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
(2015)
Article
Nanoscience & Nanotechnology
Aaron F. Cipriano, Natalie De Howitt, Shannon C. Gott, Christopher Miller, Masaru P. Rao, Huinan Liu
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
(2014)
Article
Engineering, Biomedical
Jaclyn Lock, Thanh Yen Nguyen, Huinan Liu
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
(2012)
Article
Engineering, Biomedical
Meriam A. Sebaa, Shan Dhillon, Huinan Liu
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
(2013)
Article
Engineering, Biomedical
Aaron F. Cipriano, Tong Zhao, Ian Johnson, Ren-Guo Guan, Salvador Garcia, Huinan Liu
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
(2013)
Article
Materials Science, Multidisciplinary
Meriam Sebaa, Thanh Yen Nguyen, Rajat K. Paul, Ashok Mulchandani, Huinan Liu
Article
Materials Science, Biomaterials
Ren-guo Guan, Aaron F. Cipriano, Zhan-yong Zhao, Jaclyn Lock, Di Tie, Tong Zhao, Tong Cui, Huinan Liu
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2013)
Article
Nanoscience & Nanotechnology
Ian Johnson, Khalid Akari, Huinan Liu
Article
Multidisciplinary Sciences
Ian Johnson, Huinan Liu
Article
Multidisciplinary Sciences
Thanh Yen Nguyen, Chee Gee Liew, Huinan Liu
Proceedings Paper
Engineering, Biomedical
Maria E. Iskandar, Jaclyn Y. Lock, Arash Aslani, Huinan Liu
PROCEEDINGS OF THE ASME INTERNATIONAL MECHANICAL ENGINEERING CONGRESS AND EXPOSITION 2011, VOL 2
(2012)