Article
Engineering, Biomedical
Zhibo Du, Zhijie Li, Peng Wang, Xinghao Wang, Jiarui Zhang, Zhuo Zhuang, Zhanli Liu
Summary: This study elucidates the effect of skull deformation on intracranial pressure (ICP) variation using both experimental and numerical models. The numerical analysis agrees with the experimental results, explaining the appearance of positive and negative ICP peaks and their synchronization with surface strain. This study has implications for medical injury diagnosis and protective equipment design.
ANNALS OF BIOMEDICAL ENGINEERING
(2022)
Review
Chemistry, Multidisciplinary
George R. E. Bradley, Maria Roldan, Panayiotis A. Kyriacou
Summary: This systematic review aimed to predict intracranial pressure (ICP) crises in patients with severe traumatic brain injury (TBI) in order to prevent secondary brain injury and improve patient outcomes. The review identified three effective approaches: long short-term memory (LSTM), Gaussian processes (GP), and logistic regression models, with area under the receiver operating characteristics curve (AUC-ROC) ranging from 0.86 to 0.95. The review also highlighted the lack of consensus on the definition of an ICP crisis, the most clinically relevant prediction horizon, and the clinical intelligibility, improvement of patient care, and ethical concerns of algorithms.
APPLIED SCIENCES-BASEL
(2023)
Article
Critical Care Medicine
Jennifer C. Laws, E. Haley Vance, Kristina A. Betters, Jessica J. Anderson, Sydney Fleishman, Christopher M. Bonfield, John C. Wellons III, Meng Xu, James C. Slaughter, Dario A. Giuse, Neal Patel, Lori C. Jordan, Michael S. Wolf
Summary: This retrospective observational study assessed the acute effects of ketamine on intracranial pressure (ICP) and cerebral perfusion pressure (CPP) in children with severe traumatic brain injury (TBI). The results showed that ketamine reduced ICP during ICP crises, but had no significant effect when used for sedation. These findings suggest that ketamine may be considered as a treatment for intracranial hypertension in children with severe TBI.
CRITICAL CARE MEDICINE
(2023)
Article
Clinical Neurology
Dmitriy Petrov, Stephen P. Miranda, Ramani Balu, Connor Wathen, Alex Vaz, Vinodh Mohan, Christian Colon, Ramon Diaz-Arrastia
Summary: The objective of this study was to develop an algorithm capable of predicting the onset of intracranial pressure (ICP) crises in patients with severe traumatic brain injury (TBI). The random forest model demonstrated the highest accuracy and area under the curve (AUC) in predicting ICP crises. If implemented in clinical workflows, this algorithm can enable earlier intervention and more effective treatment of intracranial hypertension, potentially leading to improved outcomes for patients with severe TBI.
JOURNAL OF NEUROSURGERY
(2023)
Article
Medicine, General & Internal
Yingchi Shan, Yihua Li, Xuxu Xu, Junfeng Feng, Xiang Wu, Guoyi Gao
Summary: This study aimed to establish a noninvasive method for assessing ICP levels in TBI patients through investigating CT HU features. The HU model showed the highest ability to predict intracranial hypertension, especially in patients with unilateral injury. It achieved the highest F1 score in different classifications of ICP levels.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Clinical Neurology
Jon Perez-Barcena, Catalina Crespi, Guillem Frontera, Juan Antonio Llompart-Pou, Osman Salazar, Victor Goliney, Javier Ibanez, M. Ross Bullock, Juan Pablo de Rivero Vaccari
Summary: This study found that in patients with TBI, the protein levels of caspase-1 in CSF are positively correlated with high ICP and poor prognosis. Especially on the 2nd and 3rd day after injury, the levels of caspase-1 in CSF are higher. Early levels of caspase-1 in CSF are not only higher in absolute value, but also associated with poor outcomes.
JOURNAL OF NEUROSURGERY
(2021)
Article
Emergency Medicine
Gaku Fujiwara, Yohei Okada, Wataru Ishii, Ryoji Iizuka, Mamoru Murakami, Takehiko Sakakibara, Tarumi Yamaki, Naoya Hashimoto
Summary: The study found that skull fracture is associated with in-hospital mortality among patients with severe traumatic brain injury, and patients with both skull base and skull vault fractures have a higher mortality rate.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Clinical Neurology
Scott T. Miller, Candice F. Cooper, Paul Elsbernd, Joseph Kerwin, Ricardo Mejia-Alvarez, Adam M. Willis
Summary: Blast traumatic brain injury is a common occurrence in modern military conflicts and may be caused by damage to intracranial mechanical interfaces. Both neuropathological and clinical findings suggest that injury occurs at material interfaces within the brain tissue, which could be key in understanding how blast overpressures lead to intracranial damage.
FRONTIERS IN NEUROLOGY
(2021)
Article
Physiology
Jun Zhu, Yingchi Shan, Yihua Li, Jiaqi Liu, Xiang Wu, Guoyi Gao
Summary: The present study aimed to investigate the clinical significance of the spindle wave morphology in intracranial pressure (ICP) monitoring of traumatic brain injury (TBI) patients. The study found that patients with spindle waves had higher Glasgow Coma Scale scores at discharge, a greater improvement in scores during hospitalization, and better 6-month Glasgow Outcome Scale-Extended scores compared to the control group. Furthermore, the occurrence of spindle waves was associated with significant improvements in physiological parameters such as ICP, pulse amplitude, and correlation coefficient.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Medicine, General & Internal
Ki-Hong Kim, Heejin Kim, Kyoung-Jun Song, Sang-Do Shin, Hee-Chan Kim, Hyouk-Jae Lim, Yoonjic Kim, Hyun-Jeong Kang, Ki-Jeong Hong
Summary: The study aimed to develop an EEG-based prediction model for increased intracranial pressure (IICP) in a porcine TBI model. Single-channel EEG data were collected and four algorithms were used to predict IICP. The SVM model showed the best performance with the highest AUC value.
Review
Clinical Neurology
Jetan Badhiwala, Angela Lumba-Brown, Gregory W. J. Hawryluk, Jamshid Ghajar
Summary: External lumbar drainage (ELD) has an immediate significant effect on intracranial pressure (ICP) in patients with traumatic brain injury (TBI), but the durable effect and impact on neurological outcomes are uncertain. ELD appears to be safe with low risk of complications, warranting further high-quality investigation into its potential application in severe TBI with refractory intracranial hypertension.
Article
Critical Care Medicine
Agnieszka Kazimierska, Agnieszka Uryga, Cyprian Mataczynski, Marek Czosnyka, Erhard W. Lang, Magdalena Kasprowicz
Summary: This study investigates the relationship between intracranial pressure pulse shape and CT features in traumatic brain injury patients. The results reveal that pulse shape index is associated with intracranial mass lesions (including midline shift and space-occupying lesions) and correlates significantly with the extent of the lesions and CT scores.
Article
Behavioral Sciences
Nicholas S. Race, Katharine D. Andrews, Elizabeth A. Lungwitz, Sasha M. Vega Alvarez, Timothy R. Warner, Glen Acosta, Jiayue Cao, Kun-han Lu, Zhongming Liu, Amy D. Dietrich, Sreeparna Majumdar, Anantha Shekhar, William A. Truitt, Riyi Shi
Summary: TBI is associated with increased risk for mental health disorders, and deficits in psychosocial processing may contribute to post-TBI mental health issues. A pre-clinical investigation using rats found that a single mild blast TBI induced impairment of psychosocial processing in the absence of other confounding factors, and this impairment may be related to acute upregulations of an oxidative stress metabolite.
BEHAVIOURAL BRAIN RESEARCH
(2021)
Article
Critical Care Medicine
Tatiana Birg, Fabrizio Ortolano, Eveline J. A. Wiegers, Peter Smielewski, Yan Savchenko, Bogdan A. Ianosi, Raimund Helbok, Sandra Rossi, Marco Carbonara, Tommaso Zoerle, Nino Stocchetti
Summary: Fever is frequent after traumatic brain injury (TBI), and it may influence brain physiology by affecting intracranial pressure (ICP) and cerebral perfusion pressure (CPP). A study revealed an association between brain temperature (BT) exceeding 37.5 degrees Celsius and higher ICP levels, but not for lower BT ranges. Rapid temperature changes seem to have a significant impact on ICP and CPP.
NEUROCRITICAL CARE
(2021)
Article
Medicine, General & Internal
Ki Hong Kim, Young Sun Ro, Hanna Yoon, Stephen Gyung Won Lee, Eujene Jung, Sung Bae Moon, Gwan Jin Park, Sang Do Shin
Summary: This study found that serum zinc levels in acute TBI patients are associated with long-term survival and neurological outcomes, with the low zinc group showing a higher risk of 6-month mortality and disability.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, Legal
Donald J. Johnson, David E. Raymond, Cynthia Chen, Matthew Quon, Julian Lis, Mo Re Choi, Christopher Lopez, Aileen Han, Ray D. de Leon, Cynthia Bir
JOURNAL OF FORENSIC SCIENCES
(2018)
Article
Critical Care Medicine
Morgan Schellenberg, Kenji Inaba, Jayun Cho, James M. Tatum, Galinos Barmparas, Aaron Strumwasser, Daniel Grabo, Cynthia Bir, Alexander Eastman, Demetrios Demetriades
JOURNAL OF TRAUMA AND ACUTE CARE SURGERY
(2017)
Article
Sport Sciences
Christopher Madias, Barry J. Maron, Nathan Dau, Nathan A. Mark Estes, Cynthia Bir, Mark S. Link
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
(2018)
Article
Engineering, Multidisciplinary
Meng J. Zhao, Anne R. Driscoll, Srijan Sengupta, Ronald D. Fricker, Dan J. Spitzner, William H. Woodall
QUALITY AND RELIABILITY ENGINEERING INTERNATIONAL
(2018)
Article
Multidisciplinary Sciences
Meng J. Zhao, Anne R. Driscoll, Srijan Sengupta, Nathaniel T. Stevens, Ronal D. Fricker, William H. Woodall
Article
Engineering, Mechanical
Monzer Al Khalil, Hassan Frissane, Lorenzo Taddei, Shuangshuang Meng, Nadhir Lebaal, Frederic Demoly, Cynthia Bir, Sebastien Roth
EXTREME MECHANICS LETTERS
(2019)
Article
Engineering, Industrial
Burcu Aytacoglu, Anne R. Driscoll, William H. Woodall
Summary: This study proposes a new method to keep the conditional false alarm rate (CFAR) of the MEWMA control chart constant over time and validates the effectiveness of this method through simulations. Dynamic probability control limits (DPCLs) adapt automatically to changes in sample size, ensuring that the CFAR remains at the specified value.
JOURNAL OF QUALITY TECHNOLOGY
(2022)
Article
Engineering, Industrial
Nathaniel T. Stevens, James D. Wilson, Anne R. Driscoll, Ian McCulloh, George Michailidis, Cecile Paris, Kamran Paynabar, Marcus B. Perry, Mostafa Reisi-Gahrooei, Srijan Sengupta, Ross Sparks
Summary: In this article, the panelists discuss the definition of network monitoring and its relation to other terms like network surveillance and network change-point detection. The ambiguity and contradictions associated with these terms are highlighted, and the wide applicability of network monitoring tools and research is emphasized.
QUALITY ENGINEERING
(2021)
Article
Engineering, Industrial
Nathaniel T. Stevens, James D. Wilson, Anne R. Driscoll, Ian McCulloh, George Michailidis, Cecile Paris, Peter Parker, Kamran Paynabar, Marcus B. Perry, Mostafa Reisi-Gahrooei, Srijan Sengupta, Ross Sparks
Summary: This paper discusses the similarities and differences between traditional statistical process monitoring and network monitoring, highlighting the challenges and open problems in contemporary network monitoring research. The panelists also explore potential outlets and avenues for disseminating such research.
QUALITY ENGINEERING
(2021)
Editorial Material
Engineering, Industrial
Nathaniel T. Stevens, James D. Wilson, Anne R. Driscoll, Ian McCulloh, George Michailidis, Cecile Paris, Peter Parker, Kamran Paynabar, Marcus B. Perry, Mostafa Reisi-Gahrooei, Srijan Sengupta, Ross Sparks
Summary: Research in network monitoring involves a wide range of disciplines, including mathematics, physics, computer science, and statistics. The interdisciplinary nature is seen as beneficial for driving innovation in the field, but there are notable barriers that limit its full potential.
QUALITY ENGINEERING
(2021)
Article
Engineering, Industrial
Nathaniel T. Stevens, James D. Wilson, Anne R. Driscoll, Ian McCulloh, George Michailidis, Cecile Paris, Kamran Paynabar, Marcus B. Perry, Mostafa Reisi-Gahrooei, Srijan Sengupta, Ross Sparks
Summary: The study and use of network monitoring methodology is influenced by the needs of government, industry, and technology sectors, each of which plays an important role in the innovation of network monitoring techniques.
QUALITY ENGINEERING
(2021)
Article
Engineering, Biomedical
Cynthia Bir, Monica Wong, Rodrigo Villalta, Meghan Lewis, Donald Sherman, Erika Matheis, Kenji Inaba, Karin Rafaels
Summary: The feasibility of a surgical simulation model developed to detect soft tissue injuries during ballistic impact was tested. Data from real-world cases was used to evaluate the model's effectiveness. Limitations and future work were also discussed.
ANNALS OF BIOMEDICAL ENGINEERING
(2023)
Article
Engineering, Multidisciplinary
Burcu Aytacoglu, Anne R. R. Driscoll, William H. H. Woodall
Summary: Dynamic control limits are useful in designing control charts when there are changes in sample sizes, risk scores, or other covariate values over time. Computer simulation can be used to control the false alarm rate and in-control run length properties. The approach of using dynamic control limits is demonstrated with the design of adaptive exponentially weighted moving average (AEWMA) control charts.
QUALITY AND RELIABILITY ENGINEERING INTERNATIONAL
(2023)
Article
Public, Environmental & Occupational Health
Cynthia Bir, Ricardo Padillo, Pranav Rajaram, Kenji Inaba
INTERNATIONAL JOURNAL OF INJURY CONTROL AND SAFETY PROMOTION
(2020)
Review
Computer Science, Information Systems
William H. Woodall, Anne R. Driscoll, Douglas C. Montgomery
Summary: This review article discusses the literature on statistical process monitoring methods based on neutrosophic principles, questioning underlying assumptions and raising important questions. These issues need to be addressed before taking this methodology seriously.
Article
Biophysics
Nathan D. Camarillo, Rafael Jimenez-Silva, Frances T. Sheehan
Summary: This article discusses the statistical dependence between multiple measurements from the same participant and provides recommendations for using these measurements when they are not independent.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
J. Huet, A. -S. Boureau, A. Sarcher, C. Cornu, A. Nordez
Summary: Standard compression in freehand 3D ultrasound induces a bias in volume calculations, but minimal compression and gel pad methods have similar results. With a trained examiner and precautions, the bias can be minimized and become acceptable in clinical applications.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
C. Lariviere, A. H. Eskandari, H. Mecheri, F. Ghezelbash, D. Gagnon, A. Shirazi-Adl
Summary: Recent developments in musculoskeletal modeling have focused on model customization. Personalization of the spine profile may affect estimates of spinal loading and stability. This study investigates the biomechanical consequences of changes in the spinal profile and finds that personalizing the spine profile has medium to large effects on trunk muscle forces and negligible to small effects on spinal loading and stability.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Luke T. Mattar, Arash B. Mahboobin, Adam J. Popchak, William J. Anderst, Volker Musahl, James J. Irrgang, Richard E. Debski
Summary: Exercise therapy fails in about 25.0% of cases for individuals with rotator cuff tears, and one reason for this failure may be the inability to strengthen and balance the muscle forces that keep the humeral head in the correct position. This study developed computational musculoskeletal models to compare the net muscle force before and after exercise therapy between successfully and unsuccessfully treated patients. The study found that unsuccessfully treated patients had less inferiorly oriented net muscle forces, which may increase the risk of impingement.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Natsuki Sado, Takeshi Edagawa, Toshihide Fujimori, Shogo Hashimoto, Yoshikazu Okamoto, Takahito Nakajima
Summary: The existing methods for predicting hip and lumbosacral joint centres in Japanese adults are biased and differ between sexes. We propose new regression equations that consider soft-tissue thickness, sex differences, and a height-directional measure, and validate them using leave-one-out cross-validation.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Peimin Yu, Xuanzhen Cen, Qichang Mei, Alan Wang, Yaodong Gu, Justin Fernandez
Summary: This study aimed to explore the intra-foot biomechanical differences among individuals with chronic ankle instability (CAI), copers, and healthy individuals during dynamic tasks. The study found that copers and CAI individuals had smaller dorsiflexion angles and copers presented a more eversion position compared to healthy participants. Copers also had greater dorsiflexion angles in the metatarsophalangeal joint and more inversion moments in the subtalar joint during certain tasks. These findings can help in designing interventions to restore ankle joint functions in CAI individuals.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Jon Skovgaard Jensen, Anders Holsgaard-Larsen, Anders Stengaard Sorensen, Per Aagaard, Jens Bojsen-Moller
Summary: This study investigates the biomechanical effects of robot-assisted body weight unloading (BWU) on gait patterns in healthy young adults. The results show that dynamic robot-assisted BWU enables reduced kinetic requirements without distorting biomechanically normal gait patterns during overground walking.
JOURNAL OF BIOMECHANICS
(2024)