Article
Peripheral Vascular Disease
Ryan J. Pewowaruk, Claudia Korcarz, James H. Stein, David Bluemke, Yacob Tedla, Adam D. Gepner
Summary: This study compared the associations of several arterial stiffness calculations in a large, multiethnic cohort and found that different methods of calculating local arterial stiffness largely gave equivalent results, indicating that the variety of different arterial stiffness calculations in use do not cause inconsistent findings.
JOURNAL OF HYPERTENSION
(2023)
Article
Peripheral Vascular Disease
Bart Spronck, Isabella Tan, Koen D. Reesink, Dana Georgevsky, Tammo Delhaas, Alberto P. Avolio, Mark Butlin
Summary: The study found that measured and calculated PWV have different dependencies on heart rate (HR) and blood pressure (BP), potentially due to approximations made in using systolic and diastolic values to calculate distensibility.
JOURNAL OF HYPERTENSION
(2021)
Article
Cardiac & Cardiovascular Systems
Yasmeen M. Farra, Jacqueline Matz, Bhama Ramkhelawon, Jessica M. Oakes, Chiara Bellini
Summary: The study revealed that chronic cigarette smoking reduces the mechanical functionality of the aorta, causes morphometric alterations in distinct segments of the aorta, and accelerates the progression of atherosclerosis. Exposed mice showed decreased ability of the aorta to store elastic energy and reduced aortic distensibility. Additionally, a more vulnerable atherosclerotic phenotype was observed in exposed vessels.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
(2021)
Article
Medicine, General & Internal
Paolo Salvi, Andrea Grillo, Sylvie Gautier, Luca Montaguti, Fausto Brunacci, Francesca Severi, Lucia Salvi, Enzo Pretolani, Gianfranco Parati, Athanase Benetos
Summary: This study evaluated the circulatory adaptive mechanisms at high altitudes. The results showed that in lowlander Europeans, altitude increase caused a slight but significant increase in systolic blood pressure and pulse pressure; and norepinephrine significantly increased after staying at high altitude. Furthermore, altitude increase in lowlanders resulted in an increase in arterial pulse wave velocity, while no significant differences were observed between highlander and lowlander in hemodynamic parameters at high altitudes.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Multidisciplinary Sciences
Beatrice Romier, Cedric Dray, Laetitia Vanalderwiert, Amandine Wahart, Thinhinane Hocine, Alizee Dortignac, Christian Garbar, Corinne Garbar, Camille Boulagnon, Nicole Bouland, Pascal Maurice, Amar Bennasroune, Herve Sartelet, Laurent Martiny, Laurent Duca, Philippe Valet, Sebastien Blaise
Summary: Recent studies have shown that apelin deficiency in mice leads to vascular stiffening and wall remodeling. The absence of apelin expression results in inflammation of adipose tissue and ECM remodeling, affecting vascular homeostasis.
SCIENTIFIC REPORTS
(2021)
Article
Medicine, General & Internal
Paolo Salvi, Filippo Valbusa, Anna Kearney-Schwartz, Carlos Labat, Andrea Grillo, Gianfranco Parati, Athanase Benetos
Summary: This study found a significant inverse correlation between carotid-femoral pulse wave velocity and carotid distensibility, indicating a close relationship between aortic stiffness evaluated by the propagative method and local carotid cross-sectional distensibility.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Marina Cecelja, Bram Ruijsink, Esther Puyol-Anton, Ye Li, Harriet Godwin, Andrew P. King, Reza Razavi, Phil Chowienczyk
Summary: Automated cardiovascular magnetic resonance-derived aortic distensibility can be incorporated into routine clinical imaging and has a similar association to cardiovascular risk factors as other measures of arterial stiffness. It also predicts new-onset cardiovascular events, making it a useful tool for the measurement of vascular aging and associated cardiovascular risk.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Peripheral Vascular Disease
Kota Suzuki, Brian Claggett, Masatoshi Minamisawa, Kotaro Nochioka, Gary F. Mitchell, Inder S. Anand, Faiez Zannad, Sanjiv J. Shah, Martin Lefkowitz, Victor Shi, Marc A. Pfeffer, John J. McMurray, Scott D. Solomon
Summary: The study found that pulse pressure (PP) was associated with cardiovascular events, with higher PP linked to higher risk, and that sacubitril/valsartan could lower PP and decrease risk.
Article
Cardiac & Cardiovascular Systems
Dan Ran, Jinping Dong, He Li, Wei-Ning Lee
Summary: A new type of natural wave, called extension wave (EW), is observed in human carotid artery experiments, and is associated with arterial longitudinal stiffness. This complements the well-established pulse wave (PW) to assess direction-dependent wall elasticity of major arteries noninvasively. The proposed anisotropy index, reflecting arterial wall microstructure and function, could be a potential risk factor for screening (sub-) clinical cardiovascular diseases.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
(2021)
Article
Environmental Sciences
Adjani A. Peralta, Diane R. Gold, Mahdieh Danesh Yazdi, Yaguang Wei, Joel Schwartz
Summary: Our study found an association between short-term PM2.5 exposure and markers of arterial stiffness and central hemodynamics.
ENVIRONMENTAL RESEARCH
(2023)
Article
Cardiac & Cardiovascular Systems
O. Eiken, A. Elia, H. Skoldefors, P. Sundblad, M. E. Keramidas, R. Kolegard
Summary: This study investigated the effects of iterative exposures to moderate elevations of local intravascular pressure on arterial/arteriolar stiffness and plasma levels of vasoactive substances. The results showed that pressure training significantly reduced arterial pressure distension and induced a series of biochemical responses, suggesting that these substances may play key roles in vascular remodeling.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
(2021)
Article
Peripheral Vascular Disease
Patricia A. Metcalf, Michelle L. Meyer, Hirofumi Tanaka, Sunil K. Agarwal, B. Gwen Windham, Susan Cheng, David Couper, Aaron R. Folsom, Gerardo Heiss
Summary: This study characterized the longitudinal relationship between blood pressure and arterial stiffness, finding that adult measures of SBP were associated with later central arterial stiffness, while only contemporaneous blood pressure measurements were associated with peripheral arterial stiffness.
JOURNAL OF HYPERTENSION
(2021)
Article
Cardiac & Cardiovascular Systems
Mutaz Alkalbani, Gaurang Prabhu, Justin Lagbo, Rehan Qayyum
Summary: This study investigated the association between serum Klotho protein levels and pulse pressure, and found an inverse association suggesting that Klotho is related to arterial stiffness.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2022)
Article
Peripheral Vascular Disease
Constance Xhaard, Pierre de Villemereuil, Athanase Benetos, Erwan Bozec, Claire Dandine-Roulland, Edith Le Floch, Veronique Regnault, Patrick Lacolley, Faiez Zannad, Patrick Rossignol, Nicolas Girerd
Summary: This study aimed to estimate the heritability of PWV and BP and determine the genetic correlation between PWV and BP. The results showed that the heritability of PWV is within the same range as BP heritability. Additionally, PWV and diastolic BP were found to share common genetic determinants.
Article
Multidisciplinary Sciences
Judith Zimmermann, Michael Loecher, Fikunwa O. Kolawole, Kathrin Baeumler, Kyle Gifford, Seraina A. Dual, Marc Levenston, Alison L. Marsden, Daniel B. Ennis
Summary: This study investigated the impact of aortic wall stiffness on hemodynamic characteristics using MRI technology and aortic models. The results showed that stiffer aortic models led to higher blood pressure, changes in velocity patterns, and increased PWV, while lower temporal resolution affected the estimation of peak velocity and PWV.
SCIENTIFIC REPORTS
(2021)
Article
Engineering, Biomedical
Boran Zhou, Mohammed Alshareef, David Prim, Michael Collins, Michael Kempner, Adam Hartstone-Rose, John F. Eberth, Alexander Rachev, Tarek Shazly
ACTA BIOMATERIALIA
(2016)
Article
Engineering, Biomedical
David A. Prim, Boran Zhou, Adam Hartstone-Rose, Mark J. Uline, Tarek Shazly, John F. Eberth
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2016)
Article
Materials Science, Multidisciplinary
Shana R. Watson, Piaomu Liu, Edsel A. Pena, Michael A. Sutton, John F. Eberth, Susan M. Lessner
MICROSCOPY AND MICROANALYSIS
(2016)
Article
Multidisciplinary Sciences
Vinal Menon, Lorain Junor, Marwa Balhaj, John F. Eberth, Jay D. Potts
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
(2016)
Article
Cardiac & Cardiovascular Systems
John F. Eberth, Natasa Popovic, Vincent C. Gresham, Emily Wilson, Jay D. Humphrey
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
(2010)
Article
Engineering, Biomedical
M. R. Bersi, J. Ferruzzi, J. F. Eberth, R. L. Gleason, J. D. Humphrey
ANNALS OF BIOMEDICAL ENGINEERING
(2014)
Article
Food Science & Technology
John F. Eberth, Jack A. Neal, Francisco C. Robles Hernandez
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2012)
Article
Chemistry, Physical
C. N. Brysch, E. Wold, M. Patterson, R. Ordonez Olivares, J. F. Eberth, F. C. Robles Hernandez
JOURNAL OF ALLOYS AND COMPOUNDS
(2014)
Review
Biophysics
J. D. Humphrey, J. F. Eberth, W. W. Dye, R. L. Gleason
JOURNAL OF BIOMECHANICS
(2009)
Article
Biophysics
M. J. Collins, J. F. Eberth, E. Wilson, J. D. Humphrey
JOURNAL OF BIOMECHANICS
(2012)
Article
Materials Science, Multidisciplinary
Yi-chao Chen, John F. Eberth
JOURNAL OF THE MECHANICS AND PHYSICS OF SOLIDS
(2012)
Article
Biology
L. Cardamone, A. Valentin, J. F. Eberth, J. D. Humphrey
MATHEMATICAL MEDICINE AND BIOLOGY-A JOURNAL OF THE IMA
(2010)
Article
Cardiac & Cardiovascular Systems
Mrinmay Chakrabarti, Nadia Al-Sammarraie, Mengistu G. Gebere, Aniket Bhattacharya, Sunita Chopra, John Johnson, Edsel A. Pena, John F. Eberth, Robert E. Poelmann, Adriana C. Gittenberger-de Groot, Mohamad Azhar
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2020)
Proceedings Paper
Automation & Control Systems
Enrique Barbieri, John F. Eberth, Farrokh Attarzadeh
2011 AMERICAN CONTROL CONFERENCE
(2011)
Article
Biophysics
Nathan D. Camarillo, Rafael Jimenez-Silva, Frances T. Sheehan
Summary: This article discusses the statistical dependence between multiple measurements from the same participant and provides recommendations for using these measurements when they are not independent.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
J. Huet, A. -S. Boureau, A. Sarcher, C. Cornu, A. Nordez
Summary: Standard compression in freehand 3D ultrasound induces a bias in volume calculations, but minimal compression and gel pad methods have similar results. With a trained examiner and precautions, the bias can be minimized and become acceptable in clinical applications.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
C. Lariviere, A. H. Eskandari, H. Mecheri, F. Ghezelbash, D. Gagnon, A. Shirazi-Adl
Summary: Recent developments in musculoskeletal modeling have focused on model customization. Personalization of the spine profile may affect estimates of spinal loading and stability. This study investigates the biomechanical consequences of changes in the spinal profile and finds that personalizing the spine profile has medium to large effects on trunk muscle forces and negligible to small effects on spinal loading and stability.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Luke T. Mattar, Arash B. Mahboobin, Adam J. Popchak, William J. Anderst, Volker Musahl, James J. Irrgang, Richard E. Debski
Summary: Exercise therapy fails in about 25.0% of cases for individuals with rotator cuff tears, and one reason for this failure may be the inability to strengthen and balance the muscle forces that keep the humeral head in the correct position. This study developed computational musculoskeletal models to compare the net muscle force before and after exercise therapy between successfully and unsuccessfully treated patients. The study found that unsuccessfully treated patients had less inferiorly oriented net muscle forces, which may increase the risk of impingement.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Natsuki Sado, Takeshi Edagawa, Toshihide Fujimori, Shogo Hashimoto, Yoshikazu Okamoto, Takahito Nakajima
Summary: The existing methods for predicting hip and lumbosacral joint centres in Japanese adults are biased and differ between sexes. We propose new regression equations that consider soft-tissue thickness, sex differences, and a height-directional measure, and validate them using leave-one-out cross-validation.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Peimin Yu, Xuanzhen Cen, Qichang Mei, Alan Wang, Yaodong Gu, Justin Fernandez
Summary: This study aimed to explore the intra-foot biomechanical differences among individuals with chronic ankle instability (CAI), copers, and healthy individuals during dynamic tasks. The study found that copers and CAI individuals had smaller dorsiflexion angles and copers presented a more eversion position compared to healthy participants. Copers also had greater dorsiflexion angles in the metatarsophalangeal joint and more inversion moments in the subtalar joint during certain tasks. These findings can help in designing interventions to restore ankle joint functions in CAI individuals.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Jon Skovgaard Jensen, Anders Holsgaard-Larsen, Anders Stengaard Sorensen, Per Aagaard, Jens Bojsen-Moller
Summary: This study investigates the biomechanical effects of robot-assisted body weight unloading (BWU) on gait patterns in healthy young adults. The results show that dynamic robot-assisted BWU enables reduced kinetic requirements without distorting biomechanically normal gait patterns during overground walking.
JOURNAL OF BIOMECHANICS
(2024)