期刊
JOURNAL OF BIOMECHANICS
卷 42, 期 15, 页码 2495-2500出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.jbiomech.2009.07.017
关键词
Osteonecrosis; Animal; Hip
资金
- NSF
- Roy J. Carver Foundation
- NIH [AR46601, AR49919]
Osteonecrosis of the femoral head remains a challenging orthopaedic problem. The disease frequently progresses to femoral head collapse, leading to debilitating osteoarthritis in the affected hip(s). Since a major goal of pre-collapse interventions is to forestall the need for hip arthroplasty, it is important that any animal models used to develop or study such interventions also have a natural history of progression to femoral head collapse. The emu (Dromaius novaehollandiae), a large flightless bird native to Australia, consistently progresses to femoral head collapse when osteonecrosis is experimentally induced cryogenically. Full biomechanical characterization of the demands this animal places on its hip is an important consideration in future usage of this model. This study reports in vitro measurement of the contact stress distributions on the emu femoral head during stance phase of the gait cycle, using Fuji pressure-sensitive film. Applied hip loadings were based upon ground reaction forces and hip flexion angles recorded in vivo. The contact stress data showed reasonable homology with the human hip, both in terms of stress magnitude and sites of habitual loading on the femoral head. (C) 2009 Elsevier Ltd. All rights reserved.
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