Review
Clinical Neurology
Jacob Spencer, Steven L. Wolf, Trisha M. Kesar
Summary: Real-time gait biofeedback holds promise for improving biomechanical deficits in post-stroke individuals, but current evidence is inconsistent. Future research should address methodological inconsistencies and develop personalized biofeedback strategies.
FRONTIERS IN NEUROLOGY
(2021)
Article
Neurosciences
John W. Chow, Dobrivoje S. Stokic
Summary: Inconsistent results in temporospatial gait variability after stroke were found. It was observed that gait variability was higher in slower speeds both in stroke subjects and healthy controls, but after controlling for gait speed, only a few temporal parameters showed increased variability related to stroke.
Article
Engineering, Biomedical
Justin Huber, Nicholas Elwert, Elizabeth Salmon Powell, Philip M. Westgate, Emily Hines, Lumy Sawaki
Summary: Stroke is a major public health concern and a leading cause of long-term disability. Dynamic body weight support (DBWS) systems are popular in clinical settings, but there is limited research comparing DBWS to standard of care (SOC) in inpatient settings. This study aimed to determine if incorporating DBWS into inpatient therapy offers greater improvement for acute ischemic stroke survivors compared to SOC.
JOURNAL OF NEUROENGINEERING AND REHABILITATION
(2023)
Article
Rehabilitation
Lindsay A. Burke, William Niehaus, Marc J. Heronemus
Summary: We report a unique case of new-onset, polyarticular tophaceous gout in a patient who developed it on her hemiparetic side days after being diagnosed with a middle cerebral artery stroke. This is the first instance of an acute gout flare in a patient with no previous history of gout. The patient was effectively treated with anakinra.
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
(2023)
Article
Computer Science, Artificial Intelligence
Javier Gil-Castillo, Patricio Barria, Rolando Aguilar Cardenas, Karim Baleta Abarza, Asterio Andrade Gallardo, Angel Biskupovic Mancilla, Jose M. Azorin, Juan C. Moreno
Summary: This study examines the feasibility of using a robot-assisted therapy methodology based on the Bobath concept for gait rehabilitation in stroke patients. The results show significant positive effects on strength improvement, but limitations on range of motion.
FRONTIERS IN NEUROROBOTICS
(2022)
Article
Clinical Neurology
Yuhei Murakami, Kaoru Honaga, Hidemi Kono, Koshiro Haruyama, Tomofumi Yamaguchi, Mami Tani, Reina Isayama, Tomokazu Takakura, Akira Tanuma, Kozo Hatori, Futoshi Wada, Toshiyuki Fujiwara
Summary: This study aimed to evaluate the effect of an AI-integrated EMG-driven robot hand on patients with chronic stroke. The results showed significant improvement in motor function and spasticity in patients using the robot, which lasted for 4 weeks. This robot hand may be helpful for upper extremity rehabilitation in stroke patients.
NEUROREHABILITATION AND NEURAL REPAIR
(2023)
Article
Geriatrics & Gerontology
Kosuke Fujita, Hiroyuki Umegaki, Taeko Makino, Kazuki Uemura, Takahiro Hayashi, Aiko Inoue, Chiharu Uno, Tomoharu Kitada, Chi Hsien Huang, Hiroyuki Shimada, Masafumi Kuzuya
Summary: This study compared the short- and long-term effects of aerobic training, resistance training, and combined training on the gait performance of older adults with subjective cognitive decline. It was found that all exercise interventions had a positive short-term effect on spatiotemporal gait parameters, with resistance training showing significant effects in the long-term.
EXPERIMENTAL GERONTOLOGY
(2021)
Review
Public, Environmental & Occupational Health
Husna Ahmad Ainuddin, Muhammad Hibatullah Romli, Tengku Aizan Hamid, Mazatulfazura S. F. Salim, Lynette Mackenzie
Summary: Research on rehabilitation for falls after stroke in Southeast Asia is limited, with a focus on physical rehabilitation and traditional therapies. Individual-centric interventions are prominent, while community-based and environmental-focused studies are lacking. More innovative research is needed to advance falls prevention and intervention practice with stroke survivors.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Sport Sciences
Katie A. Conway, Keyaira L. Crudup, Michael D. Lewek, Jason R. Franz
Summary: The study showed that utilizing horizontal impeding forces in older adults can enhance their muscle strength and walking speed, leading to improved push-off intensity during walking.
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
(2021)
Review
Rehabilitation
Norah A. Alhwoaimel, Aqeel M. Alenazi, Ahmad S. Alhowimel, Bader A. Alqahtani, Mohammed M. Alshehri
Summary: This study systematically explored the effects of trunk exercises using virtual reality technology compared to conventional exercises for trunk impairment in patients with subacute and chronic strokes. The findings indicated that trunk exercises using virtual reality have a highly significant effect on reducing trunk impairment in patients with subacute and chronic stroke.
TOPICS IN STROKE REHABILITATION
(2023)
Article
Engineering, Biomedical
Raiff Simplicio da Silva, Mikhail Santos Cerqueira, Daniel Germano Maciel, Stephano Tomaz da Silva, Marianna Celeste Cordeiro de Figueiredo, Daiane Carla Rodrigues Cardoso, Sinval Bezerra Nobrega Neto, Clarissa Fernandes Bezerra, Rafael Pereira, Wouber Herickson de Brito Vieira, Tatiana Souza Ribeiro
Summary: This study verified the relationship between walking speed and neuromuscular parameters in stroke survivors and found that adjusting predictive models for assistive device use and lower limb motor function improves accuracy. These findings may have significant implications for assessing stroke individuals and developing treatment strategies.
CLINICAL BIOMECHANICS
(2022)
Article
Computer Science, Artificial Intelligence
Takuma Ii, Satoshi Hirano, Daisuke Imoto, Yohei Otaka
Summary: This study aimed to compare the effect of gait training using Welwalk and an orthosis on gait patterns in individuals with hemiparetic stroke. The results showed that gait training using Welwalk increased step length, step width, and single support phase, while suppressing abnormal gait patterns. These findings suggest that gait training using Welwalk may promote the reacquisition of a more efficient and normal gait pattern.
FRONTIERS IN NEUROROBOTICS
(2023)
Article
Pediatrics
Daniele Panzeri, Chiara Genova, Geraldina Poggi, Sandra Strazzer, Emilia Biffi
Summary: This study provides insights into the rehabilitation of children and teenagers with hemiparesis using virtual reality and biofeedback. The personalized training with visual biofeedback in a virtual reality setting appears to be effective in improving motor control, gait pattern, endurance, and functional activities in individuals with hemiparesis.
Article
Neurosciences
Zahin Alam, Nicole K. Rendos, Alex M. Vargas, Joseph Makanjuola, Trisha M. Kesar
Summary: This study found that in post-stroke individuals, the paretic leg showed earlier timing of propulsion and propulsion-related biomechanical variables compared to the non-paretic leg and able-bodied individuals. These findings have important implications for understanding the biomechanical factors underlying stroke gait impairments and guiding therapeutic interventions.
Article
Clinical Neurology
Adriana B. Conforto, Andre G. Machado, Nathalia H. V. Ribeiro, Ela B. Plow, Sook-Lei Liew, Claudia da Costa Leite, Artemis Zavaliangos-Petropulu, Isabella Menezes, Sarah M. dos Anjos, Rafael Luccas, Paul Hunter Peckham, Leonardo G. Cohen
Summary: Both RPSS and sham followed by short-duration training showed significant improvement in upper limb motor function, especially in hand strength, in subjects with stroke in the chronic phase.
NEUROREHABILITATION AND NEURAL REPAIR
(2021)
Article
Biophysics
Nicholas A. Bianco, Carolynn Patten, Benjamin J. Fregly
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME
(2018)
Article
Clinical Neurology
Qian Ding, William J. Triggs, Sahana M. Kamath, Carolynn Patten
FRONTIERS IN NEUROLOGY
(2019)
Article
Engineering, Biomedical
Shraddha Srivastava, Carolynn Patten, Steven A. Kautz
JOURNAL OF NEUROENGINEERING AND REHABILITATION
(2019)
Article
Neurosciences
Caitlin L. Banks, Virginia L. Little, Eric R. Walker, Carolynn Patten
EXPERIMENTAL BRAIN RESEARCH
(2019)
Article
Neurosciences
Virginia L. Little, Theresa E. McGuirk, Carolynn Patten
EXPERIMENTAL BRAIN RESEARCH
(2019)
Article
Neurosciences
Virginia L. Little, Lindsay A. Perry, Mae W. Mercado, Steven A. Kautz, Carolynn Patten
Article
Mathematical & Computational Biology
Di Ao, Mohammad S. Shourijeh, Carolynn Patten, Benjamin J. Fregly
FRONTIERS IN COMPUTATIONAL NEUROSCIENCE
(2020)
Article
Multidisciplinary Sciences
Lisa C. Krishnamurthy, Gabriell N. Champion, Keith M. McGregor, Venkatagiri Krishnamurthy, Aaminah Turabi, Simone R. Roberts, Joe R. Nocera, Michael R. Borich, Amy D. Rodriguez, Samir R. Belagaje, Rachael M. Harrington, Michelle L. Harris-Love, Stacy M. Harnish, Jonathan H. Drucker, Michelle Benjamin, M. Lawson Meadows, Lauren Seeds, Zvinka Z. Zlatar, Atchar Sudhyadhom, Andrew J. Butler, Amanda Garcia, Carolynn Patten, Jonathan Trinastic, Steven A. Kautz, Chris Gregory, Bruce A. Crosson
SCIENTIFIC REPORTS
(2020)
Article
Biotechnology & Applied Microbiology
Geng Li, Mohammad S. Shourijeh, Di Ao, Carolynn Patten, Benjamin J. Fregly
Summary: Muscle co-contractions can enhance stability and accuracy during limb movement but come with higher energy cost. This study investigated the feasibility of using two common Co-Contraction Index (CCI) formulations to approximate lower limb joint stiffness trends during gait. The correlations between CCI formulations and joint stiffness were found to be highly influenced by methodological choices in CCI computation.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Marleny M. Arones, Mohammad S. Shourijeh, Carolynn Patten, Benjamin J. Fregly
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2020)
Article
Multidisciplinary Sciences
David R. Young, Caitlin L. Banks, Theresa E. McGuirk, Carolynn Patten
Summary: In this study, we found that MSA could differentiate motor function in different populations, while neurophysiological parameters could differentiate high-functioning and low-functioning stroke survivors. We also discovered significant correlations between MSA and neurophysiological parameters, providing further evidence for the relationship between MSA and neural function, and highlighting the utility of combining MSA with other relevant outcomes to interpret the analysis results.
SCIENTIFIC REPORTS
(2022)
Article
Neurosciences
Sherveen Riazati, Theresa E. McGuirk, Elliott S. Perry, Wandasun B. Sihanath, Carolynn Patten
Summary: This study examined the between-day absolute reliability of gait parameters acquired with Theia3D markerless motion capture. The results showed that the markerless motion capture produced low measurement error and offered reliable gait analysis suitable for biomechanical and clinical use.
FRONTIERS IN HUMAN NEUROSCIENCE
(2022)
Article
Neurosciences
Theresa E. McGuirk, Elliott S. Perry, Wandasun B. Sihanath, Sherveen Riazati, Carolynn Patten
Summary: 3D kinematic analysis of gait has the potential to be used as a digital biomarker for identifying neuropathologies and monitoring disease progression. Image-based markerless motion capture (MLMC) using deep learning algorithms shows promise as an accessible technology in community, clinical, and rehabilitation settings. This study assessed the feasibility of implementing 3D MLMC technology outside the traditional laboratory environment and compared the measurements with a pressure-sensitive walkway system. The results showed good agreement between MLMC and the pressure-sensitive walkway system, suggesting the potential of MLMC as a tool for outcome assessment in neurorehabilitation.
FRONTIERS IN HUMAN NEUROSCIENCE
(2022)
Article
Biotechnology & Applied Microbiology
Di Ao, Marleny. M. M. Vega, Mohammad. S. S. Shourijeh, Carolynn Patten, Benjamin. J. J. Fregly
Summary: This study presents a novel computational approach to address the problem of missing EMG signals during EMG-driven model calibration. The approach combines time-varying synergy excitations extracted from measured muscle excitations to estimate unmeasured muscle excitations and residual muscle excitations.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
Marleny M. M. Vega, Geng Li, Mohammad S. S. Shourijeh, Di Ao, Robert C. C. Weinschenk, Carolynn Patten, Josep M. M. Font-Llagunes, Valerae O. O. Lewis, Benjamin J. J. Fregly
Summary: This study used a personalized neuromusculoskeletal model to predict the impact of ipsilateral psoas muscle strength on walking function following internal hemipelvectomy with custom prosthesis reconstruction. The results suggest that retention and strengthening of the psoas muscle on the operated side may be important for maximizing post-surgery walking function.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Biophysics
Nathan D. Camarillo, Rafael Jimenez-Silva, Frances T. Sheehan
Summary: This article discusses the statistical dependence between multiple measurements from the same participant and provides recommendations for using these measurements when they are not independent.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
J. Huet, A. -S. Boureau, A. Sarcher, C. Cornu, A. Nordez
Summary: Standard compression in freehand 3D ultrasound induces a bias in volume calculations, but minimal compression and gel pad methods have similar results. With a trained examiner and precautions, the bias can be minimized and become acceptable in clinical applications.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
C. Lariviere, A. H. Eskandari, H. Mecheri, F. Ghezelbash, D. Gagnon, A. Shirazi-Adl
Summary: Recent developments in musculoskeletal modeling have focused on model customization. Personalization of the spine profile may affect estimates of spinal loading and stability. This study investigates the biomechanical consequences of changes in the spinal profile and finds that personalizing the spine profile has medium to large effects on trunk muscle forces and negligible to small effects on spinal loading and stability.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Luke T. Mattar, Arash B. Mahboobin, Adam J. Popchak, William J. Anderst, Volker Musahl, James J. Irrgang, Richard E. Debski
Summary: Exercise therapy fails in about 25.0% of cases for individuals with rotator cuff tears, and one reason for this failure may be the inability to strengthen and balance the muscle forces that keep the humeral head in the correct position. This study developed computational musculoskeletal models to compare the net muscle force before and after exercise therapy between successfully and unsuccessfully treated patients. The study found that unsuccessfully treated patients had less inferiorly oriented net muscle forces, which may increase the risk of impingement.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Natsuki Sado, Takeshi Edagawa, Toshihide Fujimori, Shogo Hashimoto, Yoshikazu Okamoto, Takahito Nakajima
Summary: The existing methods for predicting hip and lumbosacral joint centres in Japanese adults are biased and differ between sexes. We propose new regression equations that consider soft-tissue thickness, sex differences, and a height-directional measure, and validate them using leave-one-out cross-validation.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Peimin Yu, Xuanzhen Cen, Qichang Mei, Alan Wang, Yaodong Gu, Justin Fernandez
Summary: This study aimed to explore the intra-foot biomechanical differences among individuals with chronic ankle instability (CAI), copers, and healthy individuals during dynamic tasks. The study found that copers and CAI individuals had smaller dorsiflexion angles and copers presented a more eversion position compared to healthy participants. Copers also had greater dorsiflexion angles in the metatarsophalangeal joint and more inversion moments in the subtalar joint during certain tasks. These findings can help in designing interventions to restore ankle joint functions in CAI individuals.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Jon Skovgaard Jensen, Anders Holsgaard-Larsen, Anders Stengaard Sorensen, Per Aagaard, Jens Bojsen-Moller
Summary: This study investigates the biomechanical effects of robot-assisted body weight unloading (BWU) on gait patterns in healthy young adults. The results show that dynamic robot-assisted BWU enables reduced kinetic requirements without distorting biomechanically normal gait patterns during overground walking.
JOURNAL OF BIOMECHANICS
(2024)