The nature of the DNA substrate influences pre-catalytic conformational changes of DNA polymerase β

Modulating the DNA polymerase β reaction equilibrium to dissect the reverse reaction

(2017) David D Shock et al.   Nature Chemical Biology

Structural Insights into the Post-Chemistry Steps of Nucleotide Incorporation Catalyzed by a DNA Polymerase

(2016) Andrew J. Reed et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A new paradigm of DNA synthesis: three-metal-ion catalysis

(2016) Wei Yang et al.   Cell and Bioscience

Induced Fit in the Selection of Correct versus Incorrect Nucleotides by DNA Polymerase β

(2015) Beth Moscato et al.   BIOCHEMISTRY

Fluorescence Resonance Energy Transfer Studies of DNA Polymerase β

(2014) Jamie B. Towle-Weicksel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Observing a DNA Polymerase Choose Right from Wrong

(2013) Bret D. Freudenthal et al.   CELL

Substrate-Dependent Millisecond Domain Motions in DNA Polymerase β

(2012) Rebecca B. Berlow et al.   JOURNAL OF MOLECULAR BIOLOGY

Role of Induced Fit in Limiting Discrimination against AZT by HIV Reverse Transcriptase

(2011) Matthew W. Kellinger et al.   BIOCHEMISTRY

Efficiency and fidelity of human DNA polymerases λ and β during gap-filling DNA synthesis

(2010) Jessica A. Brown et al.   DNA REPAIR

Oxidatively generated base damage to cellular DNA

(2010) Jean Cadet et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nucleotide-dependent conformational change governs specificity and analog discrimination by HIV reverse transcriptase

(2010) Matthew W. Kellinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Contribution of the Reverse Rate of the Conformational Step to Polymerase β Fidelity†

(2009) Marina Bakhtina et al.   BIOCHEMISTRY

An Overview of Chemical Processes That Damage Cellular DNA: Spontaneous Hydrolysis, Alkylation, and Reactions with Radicals

(2009) Kent S. Gates   CHEMICAL RESEARCH IN TOXICOLOGY

DNA Polymerase β Substrate Specificity

(2009) William A. Beard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conformational transitions in DNA polymerase I revealed by single-molecule FRET

(2009) Y. Santoso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FitSpace Explorer: An algorithm to evaluate multidimensional parameter space in fitting kinetic data

(2008) Kenneth A. Johnson et al.   ANALYTICAL BIOCHEMISTRY

Global Kinetic Explorer: A new computer program for dynamic simulation and fitting of kinetic data

(2008) Kenneth A. Johnson et al.   ANALYTICAL BIOCHEMISTRY

Fingers-Closing and Other Rapid Conformational Changes in DNA Polymerase I (Klenow Fragment) and Their Role in Nucleotide Selectivity†

(2008) Catherine M. Joyce et al.   BIOCHEMISTRY

DNA Polymerase β Fidelity:  Halomethylene-Modified Leaving Groups in Pre-Steady-State Kinetic Analysis Reveal Differences at the Chemical Transition State†

(2007) Christopher A. Sucato et al.   BIOCHEMISTRY