Mitochondrial Phosphoenolpyruvate Carboxykinase (PEPCK-M) Is a Pro-survival, Endoplasmic Reticulum (ER) Stress Response Gene Involved in Tumor Cell Adaptation to Nutrient Availability
出版年份 2014 全文链接
标题
Mitochondrial Phosphoenolpyruvate Carboxykinase (PEPCK-M) Is a Pro-survival, Endoplasmic Reticulum (ER) Stress Response Gene Involved in Tumor Cell Adaptation to Nutrient Availability
作者
关键词
-
出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 289, Issue 32, Pages 22090-22102
出版商
American Society for Biochemistry & Molecular Biology (ASBMB)
发表日期
2014-06-28
DOI
10.1074/jbc.m114.566927
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Expression of phosphoenolpyruvate carboxykinase linked to chemoradiation susceptibility of human colon cancer cells
- (2014) Ji-Won Park et al. BMC CANCER
- A Role for Mitochondrial Phosphoenolpyruvate Carboxykinase (PEPCK-M) in the Regulation of Hepatic Gluconeogenesis
- (2014) Romana Stark et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PCK2 activation mediates an adaptive response to glucose depletion in lung cancer
- (2014) K Leithner et al. ONCOGENE
- Akt-dependent Activation of the Heart 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase (PFKFB2) Isoenzyme by Amino Acids
- (2013) Laura Novellasdemunt et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PEPCK-M expression in mouse liver potentiates, not replaces, PEPCK-C mediated gluconeogenesis
- (2013) Andrés Méndez-Lucas et al. JOURNAL OF HEPATOLOGY
- PKM2 Regulates Chromosome Segregation and Mitosis Progression of Tumor Cells
- (2013) Yuhui Jiang et al. MOLECULAR CELL
- The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression
- (2013) Wafa B’chir et al. NUCLEIC ACIDS RESEARCH
- p73 regulates serine biosynthesis in cancer
- (2013) I Amelio et al. ONCOGENE
- Activating transcription factor 4-dependent induction of FGF21 during amino acid deprivation
- (2012) Ana Luísa De Sousa-Coelho et al. BIOCHEMICAL JOURNAL
- PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis
- (2012) Weiwei Yang et al. CELL
- Small Molecule Activation of PKM2 in Cancer Cells Induces Serine Auxotrophy
- (2012) Charles Kung et al. CHEMISTRY & BIOLOGY
- Resurgence of Serine: An Often Neglected but Indispensable Amino Acid
- (2012) Satish C. Kalhan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ER stress–mediated autophagy promotes Myc-dependent transformation and tumor growth
- (2012) Lori S. Hart et al. JOURNAL OF CLINICAL INVESTIGATION
- Pyruvate Kinase M2 Regulates Gene Transcription by Acting as a Protein Kinase
- (2012) Xueliang Gao et al. MOLECULAR CELL
- Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis
- (2012) Dimitrios Anastasiou et al. Nature Chemical Biology
- Progestins activate 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) in breast cancer cells
- (2011) Laura Novellasdemunt et al. BIOCHEMICAL JOURNAL
- Functional Interaction between Responses to Lactic Acidosis and Hypoxia Regulates Genomic Transcriptional Outputs
- (2011) X. Tang et al. CANCER RESEARCH
- Functional genomics reveal that the serine synthesis pathway is essential in breast cancer
- (2011) Richard Possemato et al. NATURE
- The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
- (2011) P. Walter et al. SCIENCE
- PERK promotes cancer cell proliferation and tumor growth by limiting oxidative DNA damage
- (2010) E Bobrovnikova-Marjon et al. ONCOGENE
- Evidence for an Alternative Glycolytic Pathway in Rapidly Proliferating Cells
- (2010) M. G. Vander Heiden et al. SCIENCE
- Glutamine addiction: a new therapeutic target in cancer
- (2010) David R. Wise et al. TRENDS IN BIOCHEMICAL SCIENCES
- Glioblastoma Cells Require Glutamate Dehydrogenase to Survive Impairments of Glucose Metabolism or Akt Signaling
- (2009) C. Yang et al. CANCER RESEARCH
- Endoplasmic Reticulum Stress-Induced Activation of Activating Transcription Factor 6 Decreases cAMP-Stimulated Hepatic Gluconeogenesis via Inhibition of CREB
- (2009) Hye-Young Seo et al. ENDOCRINOLOGY
- Phosphoenolpyruvate Cycling via Mitochondrial Phosphoenolpyruvate Carboxykinase Links Anaplerosis and Mitochondrial GTP with Insulin Secretion
- (2009) Romana Stark et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis
- (2009) Yiguo Wang et al. NATURE
- Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer
- (2009) R J DeBerardinis et al. ONCOGENE
- Cancer Cell Metabolism: Warburg and Beyond
- (2008) Peggy P. Hsu et al. CELL
- Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
- (2008) D. R. Wise et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started