The Essential Role of p53-up-regulated Modulator of Apoptosis (Puma) and Its Regulation by FoxO3a Transcription Factor in β-Amyloid-induced Neuron Death

Brain amyloid-β oligomers in ageing and Alzheimer’s disease

(2013) Sylvain E. Lesné et al.   BRAIN

The role of amyloid β in the pathogenesis of Alzheimer's disease

(2013) Barnabas James Gilbert   JOURNAL OF CLINICAL PATHOLOGY

PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis

(2013) Ariele Viacava Follis et al.   Nature Chemical Biology

PUMA and BIM Are Required for Oncogene Inactivation-Induced Apoptosis

(2013) G. R. Bean et al.   Science Signaling

FoxO3a is activated and executes neuron death via Bim in response to β-amyloid

(2013) P Sanphui et al.   Cell Death & Disease

Alzheimer Mechanisms and Therapeutic Strategies

(2012) Yadong Huang et al.   CELL

The BH3-Only Proteins Bim and Puma Cooperate to Impose Deletional Tolerance of Organ-Specific Antigens

(2012) Daniel H.D. Gray et al.   IMMUNITY

Preventing Alzheimer's Disease

(2012) D. J. Selkoe   SCIENCE

Inhibition of Bax protects neuronal cells from oligomeric Aβ neurotoxicity

(2012) W Kudo et al.   Cell Death & Disease

Cellular prion protein is essential for oligomeric amyloid- -induced neuronal cell death

(2011) W. Kudo et al.   HUMAN MOLECULAR GENETICS

Phosphoinositide-3-Kinase Activation Controls Synaptogenesis and Spinogenesis in Hippocampal Neurons

(2011) G. Cuesto et al.   JOURNAL OF NEUROSCIENCE

GSK3 TIPping Off p53 to Unleash PUMA

(2011) Florian J. Bock et al.   MOLECULAR CELL

Myc and PI3K/AKT signaling cooperatively repress FOXO3a-dependent PUMA and GADD45a gene expression

(2011) Stefano Amente et al.   NUCLEIC ACIDS RESEARCH

Serum-Nutrient Starvation Induces Cell Death Mediated by Bax and Puma That Is Counteracted by p21 and Unmasked by Bcl-xL Inhibition

(2011) Frédérique Braun et al.   PLoS One

Sertad1 Plays an Essential Role in Developmentaland Pathological Neuron Death

(2010) S. C. Biswas et al.   JOURNAL OF NEUROSCIENCE

Neuronal Apoptosis Induced by Endoplasmic Reticulum Stress Is Regulated by ATF4-CHOP-Mediated Induction of the Bcl-2 Homology 3-Only Member PUMA

(2010) Z. Galehdar et al.   JOURNAL OF NEUROSCIENCE

BID, BIM, and PUMA Are Essential for Activation of the BAX- and BAK-Dependent Cell Death Program

(2010) D. Ren et al.   SCIENCE

Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members

(2009) Tristan Gallenne et al.   JOURNAL OF CELL BIOLOGY

The Insulin/Akt Signaling Pathway Is Targeted by Intracellular β-Amyloid

(2009) Han-Kyu Lee et al.   MOLECULAR BIOLOGY OF THE CELL

PUMA, a potent killer with or without p53

(2009) J Yu et al.   ONCOGENE

Sp1 and p73 activate PUMA following serum starvation

(2008) L. Ming et al.   CARCINOGENESIS

The Molecular Mechanism of Endoplasmic Reticulum Stress-Induced Apoptosis in PC-12 Neuronal Cells: The Protective Effect of Insulin-Like Growth Factor I

(2008) Cheng-Gang Zou et al.   ENDOCRINOLOGY

A role for p53 in the β-amyloid-mediated regulation of the lysosomal system

(2008) Marie P. Fogarty et al.   NEUROBIOLOGY OF AGING

Potential Role of PUMA in Delayed Death of Hippocampal CA1 Neurons After Transient Global Cerebral Ischemia

(2008) Kuniyasu Niizuma et al.   STROKE

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY