The DDN Catalytic Motif Is Required for Metnase Functions in Non-homologous End Joining (NHEJ) Repair and Replication Restart

Structural Basis of Mos1 Transposase Inhibition by the Anti-retroviral Drug Raltegravir

(2014) Urszula M. Wolkowicz et al.   ACS Chemical Biology

Targeting the Transposase Domain of the DNA Repair Component Metnase to Enhance Chemotherapy

(2012) E. A. Williamson et al.   CANCER RESEARCH

Improved Mos1-mediated transgenesis in C. elegans

(2012) Christian Frøkjær-Jensen et al.   NATURE METHODS

Chk1 phosphorylation of Metnase enhances DNA repair but inhibits replication fork restart

(2012) R Hromas et al.   ONCOGENE

Biochemical Characterization of Metnase’s Endonuclease Activity and Its Role in NHEJ Repair

(2011) Brian D. Beck et al.   BIOCHEMISTRY

Crystal Structure of the HumanHsmar1-Derived Transposase Domain in the DNA Repair Enzyme Metnase,

(2010) Kristie D. Goodwin et al.   BIOCHEMISTRY

The transposase domain protein Metnase/SETMAR suppresses chromosomal translocations

(2010) Justin Wray et al.   CANCER GENETICS AND CYTOGENETICS

Metnase/SETMAR: a domesticated primate transposase that enhances DNA repair, replication, and decatenation

(2010) Montaser Shaheen et al.   GENETICA

Metnase promotes restart and repair of stalled and collapsed replication forks

(2010) Leyma P. De Haro et al.   NUCLEIC ACIDS RESEARCH

Methylation of histone H3 lysine 36 enhances DNA repair by nonhomologous end-joining

(2010) S. Fnu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nucleases: diversity of structure, function and mechanism

(2010) Wei Yang   QUARTERLY REVIEWS OF BIOPHYSICS

DNA Binding Specificity and Cleavage Activity ofPacmmarTransposase

(2009) Laurence Delaurière et al.   BIOCHEMISTRY

Molecular Architecture of the Mos1 Paired-End Complex: The Structural Basis of DNA Transposition in a Eukaryote

(2009) Julia M. Richardson et al.   CELL

Molecular domestication of transposable elements: From detrimental parasites to useful host genes

(2009) L. Sinzelle et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Metnase Mediates Resistance to Topoisomerase II Inhibitors in Breast Cancer Cells

(2009) Justin Wray et al.   PLoS One

Expression levels of the human DNA repair protein metnase influence lentiviral genomic integration

(2008) Elizabeth A. Williamson et al.   BIOCHIMIE

The human set and transposase domain protein Metnase interacts with DNA Ligase IV and enhances the efficiency and accuracy of non-homologous end-joining

(2008) Robert Hromas et al.   DNA REPAIR

Human Pso4 Is a Metnase (SETMAR)-binding Partner That Regulates Metnase Function in DNA Repair

(2008) Brian D. Beck et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The SET and transposase domain protein Metnase enhances chromosome decatenation: regulation by automethylation

(2008) E. A. Williamson et al.   NUCLEIC ACIDS RESEARCH