Blocking Metabotropic Glutamate Receptor Subtype 7 (mGlu7) via the Venus Flytrap Domain (VFTD) Inhibits Amygdala Plasticity, Stress, and Anxiety-related Behavior

Minireview: Nutrient Sensing by G Protein-Coupled Receptors

(2013) Eric M. Wauson et al.   MOLECULAR ENDOCRINOLOGY

Differential roles of mGlu7 and mGlu8 in amygdala-dependent behavior and physiology

(2013) Markus Fendt et al.   NEUROPHARMACOLOGY

Adult siRNA-induced knockdown of mGlu7 receptors reduces anxiety in the mouse

(2013) Richard M. O'Connor et al.   NEUROPHARMACOLOGY

Critical analysis of the successes and failures of homology models of G protein-coupled receptors

(2013) Supriyo Bhattacharya et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Orthosteric versus allosteric GPCR activation: The great challenge of group-III mGluRs

(2012) Peter J. Flor et al.   BIOCHEMICAL PHARMACOLOGY

Neural substrates for the distinct effects of presynaptic group III metabotropic glutamate receptors on extinction of contextual fear conditioning in mice

(2012) Alice Dobi et al.   NEUROPHARMACOLOGY

Gastrin-Releasing Peptide Signaling Plays a Limited and Subtle Role in Amygdala Physiology and Aversive Memory

(2012) Frederique Chaperon et al.   PLoS One

The Metabotropic Glutamate Receptor 7 Allosteric Modulator AMN082: A Monoaminergic Agent in Disguise?

(2011) S. J. Sukoff Rizzo et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Pharmacological interference with metabotropic glutamate receptor subtype 7 but not subtype 5 differentially affects within- and between-session extinction of Pavlovian conditioned fear

(2011) Iulia Toth et al.   NEUROPHARMACOLOGY

Behavioural consequences of two chronic psychosocial stress paradigms: Anxiety without depression

(2011) David A. Slattery et al.   PSYCHONEUROENDOCRINOLOGY

Effects of a novel metabotropic glutamate receptor 7 negative allosteric modulator, 6-(4-methoxyphenyl)-5-methyl-3-pyridin-4-ylisoxazonolo[4,5-c]pyridin-4(5H)-one (MMPIP), on the central nervous system in rodents

(2010) Hirohiko Hikichi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Metabotropic glutamate receptor 7: At the interface of cognition and emotion

(2010) Richard M. O'Connor et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The Metabotropic Glutamate Receptor mGlu7 Activates Phospholipase C, Translocates Munc-13-1 Protein, and Potentiates Glutamate Release at Cerebrocortical Nerve Terminals

(2010) Ricardo Martín et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exploration of structure-based drug design opportunities for mGluRs

(2010) Sid Topiol et al.   NEUROPHARMACOLOGY

Metabotropic glutamate receptors: From the workbench to the bedside

(2010) F. Nicoletti et al.   NEUROPHARMACOLOGY

Selective activation of metabotropic G-protein-coupled glutamate 7 receptor elicits anxiolytic-like effects in mice by modulating GABAergic neurotransmission

(2009) Katarzyna Stachowicz et al.   BEHAVIOURAL PHARMACOLOGY

Isoxazolopyridone derivatives as allosteric metabotropic glutamate receptor 7 antagonists

(2009) Masayuki Nakamura et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Context-Dependent Pharmacology Exhibited by Negative Allosteric Modulators of Metabotropic Glutamate Receptor 7

(2009) C. M. Niswender et al.   MOLECULAR PHARMACOLOGY

Gα-Subunits Differentially Alter the Conformation and Agonist Affinity of κ-Opioid Receptors†

(2008) Feng Yan et al.   BIOCHEMISTRY

Deficits in acquisition and extinction of conditioned responses in mGluR7 knockout mice

(2008) Hannelore Goddyn et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Group III mGluR7 and mGluR8 in the amygdala differentially modulate nocifensive and affective pain behaviors

(2008) Enza Palazzo et al.   NEUROPHARMACOLOGY

Target-cell-dependent plasticity within the mossy fibre-CA3 circuit reveals compartmentalized regulation of presynaptic function at divergent release sites

(2007) Kenneth A. Pelkey et al.   JOURNAL OF PHYSIOLOGY-LONDON