Binding of TPP1 Protein to TIN2 Protein Is Required for POT1a,b Protein-mediated Telomere Protection

A TIN2 dyskeratosis congenita mutation causes telomerase-independent telomere shortening in mice

(2014) D. Frescas et al.   GENES & DEVELOPMENT

TRF2-Tethered TIN2 Can Mediate Telomere Protection by TPP1/POT1

(2014) D. Frescas et al.   MOLECULAR AND CELLULAR BIOLOGY

Telomeric 3′ Overhangs Derive from Resection by Exo1 and Apollo and Fill-In by POT1b-Associated CST

(2012) Peng Wu et al.   CELL

Telomere Protection by TPP1/POT1 Requires Tethering to TIN2

(2011) Kaori K. Takai et al.   MOLECULAR CELL

Dyskeratosis congenita as a disorder of telomere maintenance

(2011) Nya D. Nelson et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations

(2011) Luis I Toledo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The genetics and clinical manifestations of telomere biology disorders

(2010) Sharon A. Savage et al.   GENETICS IN MEDICINE

A child with severe form of dyskeratosis congenita and TINF2 mutation of shelterin complex

(2010) Nazan Sarper et al.   PEDIATRIC BLOOD & CANCER

Loss of Rap1 Induces Telomere Recombination in the Absence of NHEJ or a DNA Damage Signal

(2010) A. Sfeir et al.   SCIENCE

OB Fold-containing Protein 1 (OBFC1), a Human Homolog of Yeast Stn1, Associates with TPP1 and Is Implicated in Telomere Length Regulation

(2009) Ma Wan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Telomere Protection by TPP1 Is Mediated by POT1a and POT1b

(2009) T. Kibe et al.   MOLECULAR AND CELLULAR BIOLOGY

How Shelterin Protects Mammalian Telomeres

(2008) Wilhelm Palm et al.   Annual Review of Genetics

TINF2 mutations result in very short telomeres: analysis of a large cohort of patients with dyskeratosis congenita and related bone marrow failure syndromes

(2008) A. J. Walne et al.   BLOOD

Engineered telomere degradation models dyskeratosis congenita

(2008) D. Hockemeyer et al.   GENES & DEVELOPMENT

Pot1b Deletion and Telomerase Haploinsufficiency in Mice Initiate an ATR-Dependent DNA Damage Response and Elicit Phenotypes Resembling Dyskeratosis Congenita

(2008) H. He et al.   MOLECULAR AND CELLULAR BIOLOGY

Distinct Functions of POT1 at Telomeres

(2008) K. S. Barrientos et al.   MOLECULAR AND CELLULAR BIOLOGY

A Shared Docking Motif in TRF1 and TRF2 Used for Differential Recruitment of Telomeric Proteins

(2008) Y. Chen et al.   SCIENCE