p53 Protein Regulates Hsp90 ATPase Activity and Thereby Wnt Signaling by Modulating Aha1 Expression

A molecular signature of normal breast epithelial and stromal cells from Li-Fraumeni syndrome mutation carriers

(2015)   Oncotarget

Targeting HSF1 sensitizes cancer cells to HSP90 inhibition

(2015) Yaoyu Chen et al.   Oncotarget

Inhibition of HSP90 molecular chaperones: moving into the clinic

(2013) Rocio Garcia-Carbonero et al.   LANCET ONCOLOGY

Activation and control of p53 tetramerization in individual living cells

(2013) G. Gaglia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Carnosol, a Constituent of Zyflamend, Inhibits Aryl Hydrocarbon Receptor-Mediated Activation of CYP1A1 and CYP1B1 Transcription and Mutagenesis

(2012) A. Mohebati et al.   Cancer Prevention Research

p53 mutations in cancer

(2012) Patricia A. J. Muller et al.   NATURE CELL BIOLOGY

The Co-Chaperone Hch1 Regulates Hsp90 Function Differently than Its Homologue Aha1 and Confers Sensitivity to Yeast to the Hsp90 Inhibitor NVP-AUY922

(2012) Heather Armstrong et al.   PLoS One

The Hsp90 chaperone machinery: Conformational dynamics and regulation by co-chaperones

(2011) Jing Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Pharmacological Activation of p53 in Cancer Cells

(2011) Mohammad Athar et al.   CURRENT PHARMACEUTICAL DESIGN

p53 and MicroRNA-34 Are Suppressors of Canonical Wnt Signaling

(2011) N. H. Kim et al.   Science Signaling

Mutations that increase both Hsp90 ATPase activity in vitro and Hsp90 drug resistance in vivo

(2010) Anna Zurawska et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Caught in the Akt: Regulation of Wnt Signaling in the Intestine

(2010) Eric C. Anderson et al.   GASTROENTEROLOGY

TP53 germline mutation testing in 180 families suspected of Li-Fraumeni syndrome: mutation detection rate and relative frequency of cancers in different familial phenotypes

(2010) M. W. G. Ruijs et al.   JOURNAL OF MEDICAL GENETICS

Asymmetric Activation of the Hsp90 Dimer by Its Cochaperone Aha1

(2010) Marco Retzlaff et al.   MOLECULAR CELL

HSP90 at the hub of protein homeostasis: emerging mechanistic insights

(2010) Mikko Taipale et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Anti-proliferative activity of heat shock protein (Hsp) 90 inhibitors via β-catenin/TCF7L2 pathway in adult T cell leukemia cells

(2009) Ryosuke Kurashina et al.   CANCER LETTERS

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Silencing of HSP90 Cochaperone AHA1 Expression Decreases Client Protein Activation and Increases Cellular Sensitivity to the HSP90 Inhibitor 17-Allylamino-17-Demethoxygeldanamycin

(2008) J. L. Holmes et al.   CANCER RESEARCH

Suppression of Familial Adenomatous Polyposis by CP-31398, a TP53 Modulator, in APCmin/+ Mice

(2008) C. V. Rao et al.   CANCER RESEARCH

Helicobacter pyloriVacA-induced Inhibition of GSK3 through the PI3K/Akt Signaling Pathway

(2008) Masaaki Nakayama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY