Down-regulation of the Antisense Mitochondrial Non-coding RNAs (ncRNAs) Is a Unique Vulnerability of Cancer Cells and a Potential Target for Cancer Therapy

Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling

(2014) Susann Weissmueller et al.   CELL

The RNA-binding region of human TRBP interacts with microRNA precursors through two independent domains

(2013) Matthieu P. M. H. Benoit et al.   NUCLEIC ACIDS RESEARCH

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

Dietary downregulation of mutant p53 levels via glucose restriction

(2012) Olga Catalina Rodriguez et al.   CELL CYCLE

Mutant p53: one name, many proteins

(2012) W. A. Freed-Pastor et al.   GENES & DEVELOPMENT

Expression of Mitochondrial Non-coding RNAs (ncRNAs) Is Modulated by High Risk Human Papillomavirus (HPV) Oncogenes

(2012) Claudio Villota et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Passenger deletions generate therapeutic vulnerabilities in cancer

(2012) Florian L. Muller et al.   NATURE

The microcosmos of cancer

(2012) Amaia Lujambio et al.   NATURE

Systematic Analysis of Small RNAs Associated with Human Mitochondria by Deep Sequencing: Detailed Analysis of Mitochondrial Associated miRNA

(2012) Lakshmi Sripada et al.   PLoS One

The hallmarks of cancer

(2012) Tony Gutschner et al.   RNA Biology

Exploiting Cancer Cell Vulnerabilities to Develop a Combination Therapy for Ras-Driven Tumors

(2011) Thomas De Raedt et al.   CANCER CELL

miR-218 Suppresses Nasopharyngeal Cancer Progression through Downregulation of Survivin and the SLIT2-ROBO1 Pathway

(2011) N. M. Alajez et al.   CANCER RESEARCH

Cancer Invasion and the Microenvironment: Plasticity and Reciprocity

(2011) Peter Friedl et al.   CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Apoptosis and oncogenesis: give and take in the BCL-2 family

(2011) Fabien Llambi et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The MicroRNA 15a/16–1 Cluster Down-regulates Protein Repair Isoaspartyl Methyltransferase in Hepatoma Cells

(2011) Irene Sambri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Developmental Control of Apoptosis by the Immunophilin Aryl Hydrocarbon Receptor-interacting Protein (AIP) Involves Mitochondrial Import of the Survivin Protein

(2011) Byoung Heon Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dicer recognizes the 5′ end of RNA for efficient and accurate processing

(2011) Jong-Eun Park et al.   NATURE

Malignant pirates of the immune system

(2011) Lixin Rui et al.   NATURE IMMUNOLOGY

Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer

(2011) H. W. Cheung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNAs in the Pathogenesis of Cancer

(2011) Francesca Lovat et al.   SEMINARS IN ONCOLOGY

Nuclear localization of the mitochondrial ncRNAs in normal and cancer cells

(2011) Eduardo Landerer et al.   CELLULAR ONCOLOGY

Survivin and IAP proteins in cell-death mechanisms

(2010) Dario C. Altieri   BIOCHEMICAL JOURNAL

TEL-AML1 regulation of survivin and apoptosis via miRNA-494 and miRNA-320a

(2010) C. Diakos et al.   BLOOD

Conditional RNA interference in vivo to study mutant p53 oncogenic gain of function on tumor malignancy

(2010) Gianluca Bossi et al.   CELL CYCLE

To fight or die—inhibitor of apoptosis proteins at the crossroad of innate immunity and death

(2010) Juanita Lopez et al.   CURRENT OPINION IN CELL BIOLOGY

Cleavage of Survivin by Granzyme M Triggers Degradation of the Survivin-X-linked Inhibitor of Apoptosis Protein (XIAP) Complex to Free Caspase Activity Leading to Cytolysis of Target Tumor Cells

(2010) Deqing Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-155Regulates Cell Survival, Growth, and Chemosensitivity by TargetingFOXO3ain Breast Cancer

(2010) William Kong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expanding the MicroRNA Targeting Code: Functional Sites with Centered Pairing

(2010) Chanseok Shin et al.   MOLECULAR CELL

Desperately seeking microRNA targets

(2010) Marshall Thomas et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The terminal loop region controls microRNA processing by Drosha and Dicer

(2010) X. Zhang et al.   NUCLEIC ACIDS RESEARCH

miRBase: integrating microRNA annotation and deep-sequencing data

(2010) A. Kozomara et al.   NUCLEIC ACIDS RESEARCH

MicroRNAs identified in highly purified liver-derived mitochondria may play a role in apoptosis

(2010) Betsy T. Kren et al.   RNA Biology

Mutant p53 mediates survival of breast cancer cells

(2009) L Y Lim et al.   BRITISH JOURNAL OF CANCER

Assembling the building blocks: structure and function of inhibitor of apoptosis proteins

(2009) P D Mace et al.   CELL DEATH AND DIFFERENTIATION

Mitochondrial gateways to cancer

(2009) Lorenzo Galluzzi et al.   MOLECULAR ASPECTS OF MEDICINE

Small silencing RNAs: an expanding universe

(2009) Megha Ghildiyal et al.   NATURE REVIEWS GENETICS

Expression of a family of noncoding mitochondrial RNAs distinguishes normal from cancer cells

(2009) V. A. Burzio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Papillomaviruses in the causation of human cancers — a brief historical account

(2009) Harald zur Hausen   VIROLOGY

Survivin: Key Regulator of Mitosis and Apoptosis and Novel Target for Cancer Therapeutics

(2008) A. C. Mita et al.   CLINICAL CANCER RESEARCH

A Ubiquitin-Proteasome Pathway for the Repair of Topoisomerase I-DNA Covalent Complexes

(2008) Chao-Po Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A starvation-induced noncoding RNA modulates expression of Dicer-regulated genes

(2008) S. Hellwig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA