Structural Determinants of the Transient Receptor Potential 1 (TRPV1) Channel Activation by Phospholipid Analogs

Regulation of TRPV1 Ion Channel by Phosphoinositide (4,5)-Bisphosphate

(2014) Eric N. Senning et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Promiscuous Activation of Transient Receptor Potential Vanilloid 1 (TRPV1) Channels by Negatively Charged Intracellular Lipids

(2013) Viktor Lukacs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of endogenous molecules in modulating pain through transient receptor potential vanilloid 1 (TRPV1)

(2013) Sara L. Morales-Lázaro et al.   JOURNAL OF PHYSIOLOGY-LONDON

An LPA Species (18:1 LPA) Plays Key Roles in the Self-Amplification of Spinal LPA Production in the Peripheral Neuropathic Pain Model

(2013) Lin Ma et al.   Molecular Pain

TRPV1 structures in distinct conformations reveal activation mechanisms

(2013) Erhu Cao et al.   NATURE

TRPV1 Channels Are Intrinsically Heat Sensitive and Negatively Regulated by Phosphoinositide Lipids

(2013) Erhu Cao et al.   NEURON

Omega-3 fatty acids lower blood pressure by directly activating large-conductance Ca2+-dependent K+ channels

(2013) T. Hoshi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The position of the double bond in monounsaturated free fatty acids is essential for the inhibition of the nicotinic acetylcholine receptor

(2012) Vanesa L. Perillo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Lysophosphatidic acid: Chemical signature of neuropathic pain

(2012) Hiroshi Ueda et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Inflammatory stimuli up-regulate transient receptor potential vanilloid-1 expression in human bronchial fibroblasts

(2012) Laura R. Sadofsky et al.   EXPERIMENTAL LUNG RESEARCH

Structural Requirements of Membrane Phospholipids for M-type Potassium Channel Activation and Binding

(2012) Vsevolod Telezhkin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct subunit contributions to the activation of M-type potassium channels by PI(4,5)P2

(2012) Vsevolod Telezhkin et al.   JOURNAL OF GENERAL PHYSIOLOGY

Dual-Mode Phospholipid Regulation of Human Inward Rectifying Potassium Channels

(2011) Wayland W.L. Cheng et al.   BIOPHYSICAL JOURNAL

The thermo-TRP ion channel family: properties and therapeutic implications

(2011) Laura Vay et al.   BRITISH JOURNAL OF PHARMACOLOGY

Localization of the PIP2 Sensor of TRPV1 Ion Channels

(2011) Carmen A. Ufret-Vincenty et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antinociceptive Effect of Cyclic Phosphatidic Acid and Its Derivative on Animal Models of Acute and Chronic Pain

(2011) Yasutaka Kakiuchi et al.   Molecular Pain

Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2

(2011) Scott B. Hansen et al.   NATURE

Lysophosphatidic acid directly activates TRPV1 through a C-terminal binding site

(2011) Andrés Nieto-Posadas et al.   Nature Chemical Biology

Transient receptor potential channels as therapeutic targets

(2011) Magdalene M. Moran et al.   NATURE REVIEWS DRUG DISCOVERY

LPA Receptors: Subtypes and Biological Actions

(2010) Ji Woong Choi et al.   Annual Review of Pharmacology and Toxicology

Ligand docking and binding site analysis with PyMOL and Autodock/Vina

(2010) Daniel Seeliger et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Phospholipase D2-Dependent Inhibition of the Nuclear Hormone Receptor PPARγ by Cyclic Phosphatidic Acid

(2010) Tamotsu Tsukahara et al.   MOLECULAR CELL

Involvement of Lysophosphatidic Acid in Bone Cancer Pain by Potentiation of TRPV1 via PKCe Pathway in Dorsal Root Ganglion Neurons

(2010) Hai-Li Pan et al.   Molecular Pain

n→π* interactions in proteins

(2010) Gail J Bartlett et al.   Nature Chemical Biology

Evaluating dual activity LPA receptor pan-antagonist/autotaxin inhibitors as anti-cancer agents in vivo using engineered human tumors

(2009) Xiaoyu Xu et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Lysophosphatidic acid (LPA) receptors: Signaling properties and disease relevance

(2009) Mu-En Lin et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Determinants of Molecular Specificity in Phosphoinositide Regulation

(2008) Rebecca M. Klein et al.   JOURNAL OF BIOLOGICAL CHEMISTRY