Identification of Palmitoyltransferase and Thioesterase Enzymes That Control the Subcellular Localization of Axon Survival Factor Nicotinamide Mononucleotide Adenylyltransferase 2 (NMNAT2)

Palmitoylation and the trafficking of peripheral membrane proteins

(2013) Luke H. Chamberlain et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Mechanism and function of DHHC S-acyltransferases: Figure 1

(2013) Maurine E. Linder et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Dynamic Palmitoylation Links Cytosol-Membrane Shuttling of Acyl-protein Thioesterase-1 and Acyl-protein Thioesterase-2 with That of Proto-oncogene H-Ras Product and Growth-associated Protein-43

(2013) Eryan Kong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interplay of Palmitoylation and Phosphorylation in the Trafficking and Localization of Phosphodiesterase 10A: Implications for the Treatment of Schizophrenia

(2013) E. I. Charych et al.   JOURNAL OF NEUROSCIENCE

Rescue of Peripheral and CNS Axon Defects in Mice Lacking NMNAT2

(2013) J. Gilley et al.   JOURNAL OF NEUROSCIENCE

Axonal transport deficits and neurodegenerative diseases

(2013) Stéphanie Millecamps et al.   NATURE REVIEWS NEUROSCIENCE

Memory and synaptic deficits in Hip14/DHHC17 knockout mice

(2013) A. J. Milnerwood et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deletions within its subcellular targeting domain enhance the axon protective capacity of Nmnat2 in vivo

(2013) Stefan Milde et al.   Scientific Reports

Subcellular Localization Determines the Stability and Axon Protective Capacity of Axon Survival Factor Nmnat2

(2013) Stefan Milde et al.   PLOS BIOLOGY

Distinct Acyl Protein Transferases and Thioesterases Control Surface Expression of Calcium-activated Potassium Channels

(2012) Lijun Tian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Confirming Target Engagement for Reversible Inhibitors in Vivo by Kinetically Tuned Activity-Based Probes

(2012) Alexander Adibekian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

SCG10 is a JNK target in the axonal degeneration pathway

(2012) J. E. Shin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Acyl Protein Thioesterases 1 and 2 as the Cellular Targets of the Ras-Signaling Modulators Palmostatin B and M

(2011) Marion Rusch et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Inhibiting the palmitoylation/depalmitoylation cycle selectively reduces the growth of hematopoietic cells expressing oncogenic Nras

(2011) J. Xu et al.   BLOOD

Altered palmitoylation and neuropathological deficits in mice lacking HIP14

(2011) R. R. Singaraja et al.   HUMAN MOLECULAR GENETICS

BIMEL, an intrinsically disordered protein, is degraded by 20S proteasomes in the absence of poly-ubiquitylation

(2011) C. M. Wiggins et al.   JOURNAL OF CELL SCIENCE

Subcellular Golgi localization of stathmin family proteins is promoted by a specific set of DHHC palmitoyl transferases

(2011) Aurore D. Levy et al.   MOLECULAR BIOLOGY OF THE CELL

DHHC palmitoyl transferases: substrate interactions and (patho)physiology

(2011) Jennifer Greaves et al.   TRENDS IN BIOCHEMICAL SCIENCES

Refining the minimal sequence required for ERK1/2-dependent poly-ubiquitination and proteasome-dependent turnover of BIM

(2010) Ceri M. Wiggins et al.   CELLULAR SIGNALLING

Isoform-specific Targeting and Interaction Domains in Human Nicotinamide Mononucleotide Adenylyltransferases

(2010) Corinna Lau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Palmitoylation of the SNAP25 Protein Family

(2010) Jennifer Greaves et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression, Localization, and Biochemical Characterization of Nicotinamide Mononucleotide Adenylyltransferase 2

(2010) Paul R. Mayer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Small-molecule inhibition of APT1 affects Ras localization and signaling

(2010) Frank J Dekker et al.   Nature Chemical Biology

Acyl-Protein Thioesterase 2 Catalizes the Deacylation of Peripheral Membrane-Associated GAP-43

(2010) Vanesa M. Tomatis et al.   PLoS One

Endogenous Nmnat2 Is an Essential Survival Factor for Maintenance of Healthy Axons

(2010) Jonathan Gilley et al.   PLOS BIOLOGY

Thioesterase activity and subcellular localization of acylprotein thioesterase 1/lysophospholipase 1

(2009) Tohko Hirano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Neuronal palmitoyl acyl transferases exhibit distinct substrate specificity

(2009) Kun Huang et al.   FASEB JOURNAL

The Hydrophobic Cysteine-rich Domain of SNAP25 Couples with Downstream Residues to Mediate Membrane Interactions and Recognition by DHHC Palmitoyl Transferases

(2009) Jennifer Greaves et al.   MOLECULAR BIOLOGY OF THE CELL

TheWldSgene delays axonal but not somatic degeneration in a rat glaucoma model

(2008) Bogdan Beirowski et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Palmitoylation and Membrane Interactions of the Neuroprotective Chaperone Cysteine-string Protein

(2008) Jennifer Greaves et al.   JOURNAL OF BIOLOGICAL CHEMISTRY