Inherent Instability of the Retinitis Pigmentosa P23H Mutant Opsin

The cell stress machinery and retinal degeneration

(2013) Dimitra Athanasiou et al.   FEBS LETTERS

Hsp90 inhibition protects against inherited retinal degeneration

(2013) Mònica Aguilà et al.   HUMAN MOLECULAR GENETICS

P23H opsin knock-in mice reveal a novel step in retinal rod disc morphogenesis

(2013) S. Sakami et al.   HUMAN MOLECULAR GENETICS

An Ultra High-Throughput, Whole-Animal Screen for Small Molecule Modulators of a Specific Genetic Pathway in Caenorhabditis elegans

(2013) Chi K. Leung et al.   PLoS One

Proteasome overload is a common stress factor in multiple forms of inherited retinal degeneration

(2013) E. S. Lobanova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integration of the Unfolded Protein and Oxidative Stress Responses through SKN-1/Nrf

(2013) Kira M. Glover-Cutter et al.   PLoS Genetics

TUDCA, a Bile Acid, Attenuates Amyloid Precursor Protein Processing and Amyloid-β Deposition in APP/PS1 Mice

(2012) Ana F. Nunes et al.   MOLECULAR NEUROBIOLOGY

Characterization of the Proteostasis Roles of Glycerol Accumulation, Protein Degradation and Protein Synthesis during Osmotic Stress in C. elegans

(2012) Kristopher Burkewitz et al.   PLoS One

Rhodopsin Mutant P23H Destabilizes Rod Photoreceptor Disk Membranes

(2012) Mohammad Haeri et al.   PLoS One

Safranal, a Saffron Constituent, Attenuates Retinal Degeneration in P23H Rats

(2012) Laura Fernández-Sánchez et al.   PLoS One

Posttranslational Modifications of the Photoreceptor-Specific ABC Transporter ABCA4

(2011) Yaroslav Tsybovsky et al.   BIOCHEMISTRY

Key enzymes of the retinoid (visual) cycle in vertebrate retina

(2011) Philip D. Kiser et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

A review of the mammalian unfolded protein response

(2011) Anirikh Chakrabarti et al.   BIOTECHNOLOGY AND BIOENGINEERING

Heterologous expression of functional G-protein-coupled receptors in Caenorhabditis elegans

(2011) David Salom et al.   FASEB JOURNAL

Light-sensitive coupling of rhodopsin and melanopsin to Gi/o and Gq signal transduction in Caenorhabditis elegans

(2011) Pengxiu Cao et al.   FASEB JOURNAL

A Screenable in vivo Assay to Study Proteostasis Networks in Caenorhabditis elegans

(2011) A. Segref et al.   GENETICS

Probing Mechanisms of Photoreceptor Degeneration in a New Mouse Model of the Common Form of Autosomal Dominant Retinitis Pigmentosa due to P23H Opsin Mutations

(2011) Sanae Sakami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Profiling a Caenorhabditis elegans behavioral parametric dataset with a supervised K-means clustering algorithm identifies genetic networks regulating locomotion

(2011) Shijie Zhang et al.   JOURNAL OF NEUROSCIENCE METHODS

Rescue of Photoreceptor Degeneration by Curcumin in Transgenic Rats with P23H Rhodopsin Mutation

(2011) Vidyullatha Vasireddy et al.   PLoS One

Restoration of visual function in P23H rhodopsin transgenic rats by gene delivery of BiP/Grp78

(2010) M. S. Gorbatyuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Retinoids for treatment of retinal diseases

(2010) Krzysztof Palczewski   TRENDS IN PHARMACOLOGICAL SCIENCES

Inactivation of VCP/ter94 Suppresses Retinal Pathology Caused by Misfolded Rhodopsin in Drosophila

(2010) Ana Griciuc et al.   PLoS Genetics

Rhodopsin: The Functional Significance of Asn-Linked Glycosylation and Other Post-Translational Modifications

(2009) Anne R. Murray et al.   OPHTHALMIC GENETICS

Heterologous Expression and Purification of the Serotonin Type 4 Receptor from Transgenic Mouse Retina†

(2008) David Salom et al.   BIOCHEMISTRY

Different Properties of the Native and Reconstituted Heterotrimeric G Protein Transducin†

(2008) Anna Goc et al.   BIOCHEMISTRY

Pharmacological manipulation of gain-of-function and dominant-negative mechanisms in rhodopsin retinitis pigmentosa

(2008) Hugo F. Mendes et al.   HUMAN MOLECULAR GENETICS