Mitogen-activated Protein Kinase (MAPK)-regulated Interactions between Osterix and Runx2 Are Critical for the Transcriptional Osteogenic Program

Mitogen-Activated Protein Kinase Pathways in Osteoblasts

(2013) Matthew B. Greenblatt et al.   Annual Review of Cell and Developmental Biology

RUNX2 mutations in cleidocranial dysplasia

(2013) K.-E. Lee et al.   GENETICS AND MOLECULAR RESEARCH

Osterix and NO66 Histone Demethylase Control the Chromatin of Osterix Target Genes During Osteoblast Differentiation

(2013) Krishna M Sinha et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Osterix induces Col1a1 gene expression through binding to Sp1 sites in the bone enhancer and proximal promoter regions

(2012) Maria José Ortuño et al.   BONE

Osterix Regulates Calcification and Degradation of Chondrogenic Matrices through Matrix Metalloproteinase 13 (MMP13) Expression in Association with Transcription Factor Runx2 during Endochondral Ossification

(2012) Riko Nishimura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Orphan Nuclear Receptor Chicken Ovalbumin Upstream Promoter-Transcription Factor II (COUP-TFII) Protein Negatively Regulates Bone Morphogenetic Protein 2-induced Osteoblast Differentiation through Suppressing Runt-related Gene 2 (Runx2) Activity

(2012) Kkot-Nim Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptional Regulatory Cascades in Runx2-Dependent Bone Development

(2012) Tong Ming Liu et al.   TISSUE ENGINEERING PART B-REVIEWS

Osterix is regulated by Erk1/2 during osteoblast differentiation

(2011) You Hee Choi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The transcriptional activity of osterix requires the recruitment of Sp1 to the osteocalcin proximal promoter

(2011) Corinne Niger et al.   BONE

Interactions between extracellular signal-regulated kinase 1/2 and P38 Map kinase pathways in the control of RUNX2 phosphorylation and transcriptional activity

(2011) Chunxi Ge et al.   JOURNAL OF BONE AND MINERAL RESEARCH

NELL-1, an Osteoinductive Factor, Is a Direct Transcriptional Target of Osterix

(2011) Feng Chen et al.   PLoS One

Identification of a Frameshift Mutation in Osterix in a Patient with Recessive Osteogenesis Imperfecta

(2010) Pablo Lapunzina et al.   AMERICAN JOURNAL OF HUMAN GENETICS

p38 Regulates Expression of Osteoblast-specific Genes by Phosphorylation of Osterix

(2010) María José Ortuño et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SOX9 determines RUNX2 transactivity by directing intracellular degradation

(2010) Aixin Cheng et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice

(2010) Matthew B. Greenblatt et al.   JOURNAL OF CLINICAL INVESTIGATION

Multiple functions of Osterix are required for bone growth and homeostasis in postnatal mice

(2010) X. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic Control of Bone Formation

(2009) Gerard Karsenty et al.   Annual Review of Cell and Developmental Biology

Postnatally induced inactivation of Osterix in osteoblasts results in the reduction of bone formation and maintenance

(2009) Wook-Young Baek et al.   BONE

Promoter and intron 1 polymorphisms of COL1A1 interact to regulate transcription and susceptibility to osteoporosis

(2009) H. Jin et al.   HUMAN MOLECULAR GENETICS

Common variants in the region around Osterix are associated with bone mineral density and growth in childhood

(2009) Nicholas J. Timpson et al.   HUMAN MOLECULAR GENETICS

Structural Coupling of Smad and Runx2 for Execution of the BMP2 Osteogenic Signal

(2008) Amjad Javed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BMP2 Regulates Osterix through Msx2 and Runx2 during Osteoblast Differentiation

(2008) Takuma Matsubara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Berberine Promotes Osteoblast Differentiation by Runx2 Activation With p38 MAPK

(2008) Hyun Woo Lee et al.   JOURNAL OF BONE AND MINERAL RESEARCH