An Interactive Network of Elastase, Secretases, and PAR-2 Protein Regulates CXCR1 Receptor Surface Expression on Neutrophils

Localization and Functionality of the Inflammasome in Neutrophils

(2014) Martina Bakele et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interactome Analyses of Mature γ-Secretase Complexes Reveal Distinct Molecular Environments of Presenilin (PS) Paralogs and Preferential Binding of Signal Peptide Peptidase to PS2

(2013) Amy Hye Won Jeon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Risk Factors for Bronchiectasis in Children with Cystic Fibrosis

(2013) Peter D. Sly et al.   NEW ENGLAND JOURNAL OF MEDICINE

Presenilins and  -Secretase: Structure, Function, and Role in Alzheimer Disease

(2013) B. De Strooper et al.   Cold Spring Harbor Perspectives in Medicine

Targeting CXCR1/2 Significantly Reduces Breast Cancer Stem Cell Activity and Increases the Efficacy of Inhibiting HER2 via HER2-Dependent and -Independent Mechanisms

(2012) J. K. Singh et al.   CLINICAL CANCER RESEARCH

Neutrophils Express Distinct RNA Receptors in a Non-canonical Way

(2012) Michael Berger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a tetratricopeptide repeat-like domain in the nicastrin subunit of  -secretase using synthetic antibodies

(2012) X. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alpha-1-antitrypsin is produced by human neutrophil granulocytes and their precursors and liberated during granule exocytosis

(2011) Stine N. Clemmensen et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

The role of matrix metalloproteinases in cystic fibrosis lung disease

(2011) A. Gaggar et al.   EUROPEAN RESPIRATORY JOURNAL

CXCR1andCXCR2haplotypes synergistically modulate cystic fibrosis lung disease

(2011) Michael S.D. Kormann et al.   EUROPEAN RESPIRATORY JOURNAL

Neutrophil Elastase Acts as a Biased Agonist for Proteinase-activated Receptor-2 (PAR2)

(2011) Rithwik Ramachandran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Olfactomedin 4 defines a subset of human neutrophils

(2011) Stine N. Clemmensen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Leucine-rich repeat kinase LRRK1 regulates endosomal trafficking of the EGF receptor

(2011) Hiroshi Hanafusa et al.   Nature Communications

Leukocyte cell surface proteinases: Regulation of expression, functions, and mechanisms of surface localization

(2008) C OWEN   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The Cleavage of Neutrophil Leukosialin (CD43) by Cathepsin G Releases Its Extracellular Domain and Triggers Its Intramembrane Proteolysis by Presenilin/γ-Secretase

(2008) Agnès Mambole et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interleukin-1 Receptor Type 1 Is a Substrate for γ-Secretase-dependent Regulated Intramembrane Proteolysis

(2008) Baukje M. Elzinga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY