Arrestin-dependent Angiotensin AT1Receptor Signaling Regulates Akt and mTor-mediated Protein Synthesis

The β-arrestin-biased ligand TRV120023 inhibits angiotensin II-induced cardiac hypertrophy while preserving enhanced myofilament response to calcium

(2013) Michelle M. Monasky et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The Arrestin-selective Angiotensin AT1Receptor Agonist [Sar1,Ile4,Ile8]-AngII Negatively Regulates Bradykinin B2Receptor Signaling via AT1-B2Receptor Heterodimers

(2013) Parker C. Wilson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

β-Arrestin-biased AT1R stimulation promotes cell survival during acute cardiac injury

(2012) Ki-Seok Kim et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Deciphering biased-agonism complexity reveals a new active AT1 receptor entity

(2012) Aude Saulière et al.   Nature Chemical Biology

Differential  -Arrestin-Dependent Conformational Signaling and Cellular Responses Revealed by Angiotensin Analogs

(2012) B. Zimmerman et al.   Science Signaling

The β-Arrestin Pathway-selective Type 1A Angiotensin Receptor (AT1A) Agonist [Sar1,Ile4,Ile8]Angiotensin II Regulates a Robust G Protein-independent Signaling Network

(2011) Ryan T. Kendall et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adrenal Beta-Arrestin 1 Inhibition In Vivo Attenuates Post-Myocardial Infarction Progression to Heart Failure and Adverse Remodeling Via Reduction of Circulating Aldosterone Levels

(2011) Anastasios Lymperopoulos et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The Effect of Arrestin Conformation on the Recruitment of c-Raf1, MEK1, and ERK1/2 Activation

(2011) Sergio Coffa et al.   PLoS One

Selectively Engaging  -Arrestins at the Angiotensin II Type 1 Receptor Reduces Blood Pressure and Increases Cardiac Performance

(2010) J. D. Violin et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Quantitative Phosphoproteomics Dissection of Seven-transmembrane Receptor Signaling Using Full and Biased Agonists

(2010) Gitte L. Christensen et al.   MOLECULAR & CELLULAR PROTEOMICS

Global phosphorylation analysis of  -arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR)

(2010) K. Xiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diversity in arrestin function

(2009) Ryan T. Kendall et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Obestatin stimulates Akt signalling in gastric cancer cells through β-arrestin-mediated epidermal growth factor receptor transactivation

(2009) Carlos J P Álvarez et al.   ENDOCRINE-RELATED CANCER

β-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation

(2009) Seungkirl Ahn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Independent β-Arrestin2 and Gq/Protein Kinase Cζ Pathways for ERK Stimulated by Angiotensin Type 1A Receptors in Vascular Smooth Muscle Cells Converge on Transactivation of the Epidermal Growth Factor Receptor

(2009) Jihee Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An adrenal  -arrestin 1-mediated signaling pathway underlies angiotensin II-induced aldosterone production in vitro and in vivo

(2009) A. Lymperopoulos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior

(2008) Jean-Martin Beaulieu et al.   CELL

c-Src-mediated phosphorylation of AP-2 reveals a general mechanism for receptors internalizing through the clathrin pathway

(2008) B ZIMMERMAN et al.   CELLULAR SIGNALLING

β-Arrestins Regulate Atherosclerosis and Neointimal Hyperplasia by Controlling Smooth Muscle Cell Proliferation and Migration

(2008) Jihee Kim et al.   CIRCULATION RESEARCH

β-Arrestin-mediated Signaling Regulates Protein Synthesis

(2008) Scott M. DeWire et al.   JOURNAL OF BIOLOGICAL CHEMISTRY