Aha1 Can Act as an Autonomous Chaperone to Prevent Aggregation of Stressed Proteins

Asymmetric Hsp90 N Domain SUMOylation Recruits Aha1 and ATP-Competitive Inhibitors

(2014) Mehdi Mollapour et al.   MOLECULAR CELL

An In Vivo Photo-Cross-Linking Approach Reveals a Homodimerization Domain of Aha1 in S. cerevisiae

(2014) Michael Berg et al.   PLoS One

Integration of the accelerator Aha1 in the Hsp90 co-chaperone cycle

(2013) Jing Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Primate Specific Extra Domain in the Molecular Chaperone Hsp90

(2013) Vishwadeepak Tripathi et al.   PLoS One

Structure, Function and Regulation of the Hsp90 Machinery

(2013) Johannes Buchner et al.   Biomedical Journal

Dynamic Tyrosine Phosphorylation Modulates Cycling of the HSP90-P50CDC37-AHA1 Chaperone Machine

(2012) Wanping Xu et al.   MOLECULAR CELL

Biological and Structural Basis for Aha1 Regulation of Hsp90 ATPase Activity in Maintaining Proteostasis in the Human Disease Cystic Fibrosis

(2010) Atanas V. Koulov et al.   MOLECULAR BIOLOGY OF THE CELL

Asymmetric Activation of the Hsp90 Dimer by Its Cochaperone Aha1

(2010) Marco Retzlaff et al.   MOLECULAR CELL

HSP90 at the hub of protein homeostasis: emerging mechanistic insights

(2010) Mikko Taipale et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Hsp90 molecular chaperone: an open and shut case for treatment

(2008) Laurence H. Pearl et al.   BIOCHEMICAL JOURNAL

Silencing of HSP90 Cochaperone AHA1 Expression Decreases Client Protein Activation and Increases Cellular Sensitivity to the HSP90 Inhibitor 17-Allylamino-17-Demethoxygeldanamycin

(2008) J. L. Holmes et al.   CANCER RESEARCH

Conserved Conformational Changes in the ATPase Cycle of Human Hsp90

(2008) Klaus Richter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel HSP90 chaperone complex regulates intracellular vesicle transport

(2008) G. P. Lotz et al.   JOURNAL OF CELL SCIENCE