RING Finger Protein RNF207, a Novel Regulator of Cardiac Excitation

Hsp90 prevents interaction between CHIP and HERG proteins to facilitate maturation of wild-type and mutant HERG proteins

(2013) Chisato Iwai et al.   CARDIOVASCULAR RESEARCH

Long QT syndrome: beyond the causal mutation

(2013) Ahmad S. Amin et al.   JOURNAL OF PHYSIOLOGY-LONDON

Increased expression of rififylin in a 330 kb congenic strain is linked to impaired endosomal recycling in proximal tubules

(2013) Kathirvel Gopalakrishnan   Frontiers in Genetics

Interactions between hERG and KCNQ1 α-subunits are mediated by their COOH termini and modulated by cAMP

(2012) Louise E. Organ-Darling et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Trafficking-Deficient G572R-hERG and E637K-hERG Activate Stress and Clearance Pathways in Endoplasmic Reticulum

(2012) Ying Wang et al.   PLoS One

Origin and Diversification of TRIM Ubiquitin Ligases

(2012) Ignacio Marín   PLoS One

Predicting the Functional Effect of Amino Acid Substitutions and Indels

(2012) Yongwook Choi et al.   PLoS One

The zebrafish as a novel animal model to study the molecular mechanisms of mechano-electrical feedback in the heart

(2012) Andreas A. Werdich et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

The Hsp90 chaperone machinery: Conformational dynamics and regulation by co-chaperones

(2011) Jing Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Common Genetic Variants, QT Interval, and Sudden Cardiac Death in a Finnish Population-Based Study

(2011) Peter A. Noseworthy et al.   Circulation-Cardiovascular Genetics

Augmented Rififylin Is a Risk Factor Linked to Aberrant Cardiomyocyte Function, Short-QT Interval and Hypertension

(2011) Kathirvel Gopalakrishnan et al.   HYPERTENSION

TRIM family: Pleiotropy and diversification through homomultimer and heteromultimer formation

(2011) Luisa M. Napolitano et al.   IUBMB LIFE

Identification of a Kir3.4 Mutation in Congenital Long QT Syndrome

(2010) Yanzong Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Pore mutants of HERG and KvLQT1 downregulate the reciprocal currents in stable cell lines

(2010) Xiao-Qin Ren et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Identification and expression analysis of kcnh2 genes in the zebrafish

(2010) Ivone Un San Leong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

E2s: structurally economical and functionally replete

(2010) Dawn M. Wenzel et al.   BIOCHEMICAL JOURNAL

Reciprocal Control of hERG Stability by Hsp70 and Hsc70 With Implication for Restoration of LQT2 Mutant Stability

(2010) Peili Li et al.   CIRCULATION RESEARCH

Recent progress in congenital long QT syndrome

(2010) Jonathan T Lu et al.   CURRENT OPINION IN CARDIOLOGY

Wnt11 patterns a myocardial electrical gradient through regulation of the L-type Ca2+ channel

(2010) Daniela Panáková et al.   NATURE

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

(2010) Nona Sotoodehnia et al.   NATURE GENETICS

Genome-wide association study of antipsychotic-induced QTc interval prolongation

(2010) K Åberg et al.   PHARMACOGENOMICS JOURNAL

RING Domain E3 Ubiquitin Ligases

(2009) Raymond J. Deshaies et al.   Annual Review of Biochemistry

Drug-Sensitized Zebrafish Screen Identifies Multiple Genes, Including GINS3 , as Regulators of Myocardial Repolarization

(2009) David J. Milan et al.   CIRCULATION

Clinical Correlates and Heritability of QT Interval Duration in Blacks

(2009) Ermeg L. Akylbekova et al.   Circulation-Arrhythmia and Electrophysiology

Gene expression profiling: Classification of mice with left ventricle systolic dysfunction using microarray analysis*

(2009) Jim Wong et al.   CRITICAL CARE MEDICINE

Hsp40 Chaperones Promote Degradation of the hERG Potassium Channel

(2009) Valerie E. Walker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Common candidate gene variants are associated with QT interval duration in the general population

(2009) A. Marjamaa et al.   JOURNAL OF INTERNAL MEDICINE

Common variants at ten loci modulate the QT interval duration in the QTSCD Study

(2009) Arne Pfeufer et al.   NATURE GENETICS

Common variants at ten loci influence QT interval duration in the QTGEN Study

(2009) Christopher Newton-Cheh et al.   NATURE GENETICS

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

(2009) Prateek Kumar et al.   Nature Protocols

Posttranslational modification of voltage-dependent potassium channel Kv1.5: COOH-terminal palmitoylation modulates its biological properties

(2008) Hitesh K. Jindal et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Computational analysis of the human HSPH/HSPA/DNAJ family and cloning of a human HSPH/HSPA/DNAJ expression library

(2008) Jurre Hageman et al.   CELL STRESS & CHAPERONES

Estimation of significance thresholds for genomewide association scans

(2008) Frank Dudbridge et al.   GENETIC EPIDEMIOLOGY

Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia

(2008) S Volpi et al.   MOLECULAR PSYCHIATRY