Nodal·Gdf1 Heterodimers with Bound Prodomains Enable Serum-independent Nodal Signaling and Endoderm Differentiation

The Cell-Cycle State of Stem Cells Determines Cell Fate Propensity

(2013) Siim Pauklin et al.   CELL

Functional evaluation of ES cell-derived endodermal populations reveals differences between Nodal and Activin A-guided differentiation

(2013) A. E. Chen et al.   DEVELOPMENT

Multistep molecular mechanism for Bone morphogenetic protein extracellular transport in the Drosophila embryo

(2012) A. Sawala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Large Bioactive BMP Ligand with Distinct Signaling Properties Is Produced by Alternative Proconvertase Processing

(2012) T. Akiyama et al.   Science Signaling

Stage-specific signaling through TGF  family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells

(2011) M. C. Nostro et al.   DEVELOPMENT

Latent TGF-β structure and activation

(2011) Minlong Shi et al.   NATURE

Functional redundancy of EGF-CFC genes in epiblast and extraembryonic patterning during early mouse embryogenesis

(2010) Jianhua Chu et al.   DEVELOPMENTAL BIOLOGY

Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development

(2009) Thomas Touboul et al.   HEPATOLOGY

Antagonism between Smad1 and Smad2 signaling determines the site of distal visceral endoderm formation in the mouse embryo

(2009) Masamichi Yamamoto et al.   JOURNAL OF CELL BIOLOGY

Making a commitment: cell lineage allocation and axis patterning in the early mouse embryo

(2009) Sebastian J. Arnold et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ActRIIA and BMPRII Type II BMP Receptor Subunits Selectively Required for Smad4-Independent BMP7-Evoked Chemotaxis

(2009) Jeanette C. Perron et al.   PLoS One

Signaling Pathways Controlling Pluripotency and Early Cell Fate Decisions of Human Induced Pluripotent Stem Cells

(2009) Ludovic Vallier et al.   STEM CELLS

Riding Shotgun: A Dual Role for the Epidermal Growth Factor-Cripto/FRL-1/Cryptic Protein Cripto in Nodal Trafficking

(2009) Daniel B. Constam   TRAFFIC

Wnt, Activin, and BMP Signaling Regulate Distinct Stages in the Developmental Pathway from Embryonic Stem Cells to Blood

(2008) M. Cristina Nostro et al.   Cell Stem Cell

Cripto recruits Furin and PACE4 and controls Nodal trafficking during proteolytic maturation

(2008) Marie-Hélène Blanchet et al.   EMBO JOURNAL

Cripto promotes A–P axis specification independently of its stimulatory effect on Nodal autoinduction

(2008) Daniela D'Andrea et al.   JOURNAL OF CELL BIOLOGY

Cripto Localizes Nodal at the Limiting Membrane of Early Endosomes

(2008) M.-H. Blanchet et al.   Science Signaling