Hyper-O-GlcNAcylation Is Anti-apoptotic and Maintains Constitutive NF-κB Activity in Pancreatic Cancer Cells

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism

(2012) Haoqiang Ying et al.   CELL

EMT and Dissemination Precede Pancreatic Tumor Formation

(2012) Andrew D. Rhim et al.   CELL

Critical Role ofO-Linked β-N-Acetylglucosamine Transferase in Prostate Cancer Invasion, Angiogenesis, and Metastasis

(2012) Thomas P. Lynch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cross Talk Between O-GlcNAcylation and Phosphorylation: Roles in Signaling, Transcription, and Chronic Disease

(2011) Gerald W. Hart et al.   Annual Review of Biochemistry

O-GlcNAcylation is a novel regulator of lung and colon cancer malignancy

(2011) Wenyi Mi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Gene expression of O-GlcNAc cycling enzymes in human breast cancers

(2011) Anna Krześlak et al.   CLINICAL AND EXPERIMENTAL MEDICINE

O-GlcNAcylation plays a role in tumor recurrence of hepatocellular carcinoma following liver transplantation

(2011) Qianqian Zhu et al.   MEDICAL ONCOLOGY

Hijacking a biosynthetic pathway yields a glycosyltransferase inhibitor within cells

(2011) Tracey M Gloster et al.   Nature Chemical Biology

NF-κB promotes epithelial–mesenchymal transition, migration and invasion of pancreatic carcinoma cells

(2010) Harald J. Maier et al.   CANCER LETTERS

Snail1 is stabilized by O-GlcNAc modification in hyperglycaemic condition

(2010) Sang Yoon Park et al.   EMBO JOURNAL

Aberrant O-GlcNAcylation characterizes chronic lymphocytic leukemia

(2010) Y Shi et al.   LEUKEMIA

Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1

(2010) S A Caldwell et al.   ONCOGENE

Persistently Activated Stat3 Maintains Constitutive NF-κB Activity in Tumors

(2009) Heehyoung Lee et al.   CANCER CELL

Downregulation of nuclear factor-κB p65 subunit by small interfering RNA synergizes with gemcitabine to inhibit the growth of pancreatic cancer

(2009) Rui Kong et al.   CANCER LETTERS

CD147 silencing inhibits lactate transport and reduces malignant potential of pancreatic cancer cells in in vivo and in vitro models

(2009) W Schneiderhan et al.   GUT

Tumor Necrosis Factor-α Induces RelA Degradation via Ubiquitination at Lysine 195 to Prevent Excessive Nuclear Factor-κB Activation

(2009) Yihui Fan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of p53 enhances catalytic activity of IKK  through O-linked  -N-acetyl glucosamine modification

(2009) K. Kawauchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glutamine-dependent anapleurosis dictates glucose uptake and cell growth by regulating MondoA transcriptional activity

(2009) M. R. Kaadige et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Tumor Cell Metabolism: Cancer's Achilles' Heel

(2008) Guido Kroemer et al.   CANCER CELL

Maintenance of Constitutive I B Kinase Activity by Glycogen Synthase Kinase-3 /  in Pancreatic Cancer

(2008) W. Wilson et al.   CANCER RESEARCH

Is cancer a disease of abnormal cellular metabolism? New angles on an old idea

(2008) Ralph J Deberardinis   GENETICS IN MEDICINE

p53 regulates glucose metabolism through an IKK-NF-κB pathway and inhibits cell transformation

(2008) Keiko Kawauchi et al.   NATURE CELL BIOLOGY

NF B activation is associated with its O-GlcNAcylation state under hyperglycemic conditions

(2008) W. H. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA