The Crystal Structure of Shiga Toxin Type 2 with Bound Disaccharide Guides the Design of a Heterobifunctional Toxin Inhibitor

Discovery of Inhibitors of Shiga Toxin Type 2 by On-Plate Generation and Screening of a Focused Compound Library

(2014) Somnath Dasgupta et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The synthesis of a multivalent heterobifunctional ligand for specific interaction with Shiga toxin 2 produced by E. coli O157:H7

(2013) Jared M. Jacobson et al.   CARBOHYDRATE RESEARCH

Shiga Toxin-Producing Escherichia coli O104:H4: a New Challenge for Microbiology

(2012) Maite Muniesa et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Solid dispersion formulations of megestrol acetate with copovidone for enhanced dissolution and oral bioavailability

(2011) Soon Wook Hong et al.   ARCHIVES OF PHARMACAL RESEARCH

Lipopolysaccharide Renders Transgenic Mice Expressing Human Serum Amyloid P Component Sensitive to Shiga Toxin 2

(2011) Thomas P. Griener et al.   PLoS One

Comparison of Binding Platforms Yields Insights into Receptor Binding Differences between Shiga Toxins 1 and 2

(2010) Michael J. Flagler et al.   BIOCHEMISTRY

Salmonella enterica Serovar Typhimurium Vaccine Strains Expressing a Nontoxic Shiga-Like Toxin 2 Derivative Induce Partial Protective Immunity to the Toxin Expressed by Enterohemorrhagic Escherichia coli

(2010) R. L. G. Rojas et al.   Clinical and Vaccine Immunology

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Primary and secondary cases in Escherichia coliO157 outbreaks: a statistical analysis

(2009) Kate G Snedeker et al.   BMC INFECTIOUS DISEASES

An Orally Applicable Shiga Toxin Neutralizer Functions in the Intestine To Inhibit the Intracellular Transport of the Toxin

(2009) M. Watanabe-Takahashi et al.   INFECTION AND IMMUNITY

Differentiation between Structurally Homologous Shiga 1 and Shiga 2 Toxins by Using Synthetic Glycoconjugates

(2008) Ramesh R. Kale et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7

(2008) Gerrit Langer et al.   Nature Protocols

In vivo supramolecular templating enhances the activity of multivalent ligands: A potential therapeutic against the Escherichia coli O157 AB5 toxins

(2008) P. I. Kitov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Entropically Efficient Supramolecular Inhibition Strategy for Shiga Toxins

(2007) Pavel I. Kitov et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION