Sphingosine 1-Phosphate (S1P) Receptors 1 and 2 Coordinately Induce Mesenchymal Cell Migration through S1P Activation of Complementary Kinase Pathways

Anti-Inflammatory Effects of Sphingosine Kinase Modulation in Inflammatory Arthritis

(2014) W.-Q. Lai et al.   JOURNAL OF IMMUNOLOGY

Protein Kinase B/AKT and Focal Adhesion Kinase: Two Close Signaling Partners in Cancer

(2012) Shouye Wang et al.   Anti-Cancer Agents in Medicinal Chemistry

Sphingosine 1-phosphate receptor activation enhances BMP-2-induced osteoblast differentiation

(2012) Chieri Sato et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Building a better sphingosine kinase-1 inhibitor

(2012) Kevin R. Lynch   BIOCHEMICAL JOURNAL

Sphingosine kinase and sphingosine-1-phosphate receptors: novel therapeutic targets of rheumatoid arthritis?

(2012) Wen-Qi Lai et al.   Future Medicinal Chemistry

Higher Circulating Sphingosine 1-Phosphate Levels Are Associated with Lower Bone Mineral Density and Higher Bone Resorption Marker in Humans

(2012) Seung Hun Lee et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Sphingosine-1-phosphate activates chemokine-promoted myeloma cell adhesion and migration involving α4β1 integrin function

(2012) David García-Bernal et al.   JOURNAL OF PATHOLOGY

JAK-STAT and JAK-PI3K-mTORC1 Pathways Regulate Telomerase Transcriptionally and Posttranslationally in ATL Cells

(2012) O. Yamada et al.   MOLECULAR CANCER THERAPEUTICS

Identification of copy number alterations associated with the progression of DCIS to invasive ductal carcinoma

(2011) Clint E. Johnson et al.   BREAST CANCER RESEARCH AND TREATMENT

Does cytokine signaling link sphingolipid metabolism to host defense and immunity against virus infections?

(2011) Young-Jin Seo et al.   CYTOKINE & GROWTH FACTOR REVIEWS

CD69 Modulates Sphingosine-1-Phosphate-Induced Migration of Skin Dendritic Cells

(2011) Amalia Lamana et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Role of FAK in S1P-regulated endothelial permeability

(2011) Patrick Belvitch et al.   MICROVASCULAR RESEARCH

Sphingosine Kinase 1 Is Overexpressed and Promotes Proliferation in Human Thyroid Cancer

(2011) Hongyu Guan et al.   MOLECULAR ENDOCRINOLOGY

The tumor-suppressor gene ARHI (DIRAS3) suppresses ovarian cancer cell migration through inhibition of the Stat3 and FAK/Rho signaling pathways

(2011) D B Badgwell et al.   ONCOGENE

Sphingosine kinase 1 is critically involved in nitric oxide-mediated human endothelial cell migration and tube formation

(2010) Stephanie Schwalm et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Expression of Sphingosine Kinase-1 in Head and Neck Carcinoma

(2010) María M. Facchinetti et al.   CELLS TISSUES ORGANS

S1P1 and VEGFR-2 Form a Signaling Complex with Extracellularly Regulated Kinase 1/2 and Protein Kinase C-  Regulating ML-1 Thyroid Carcinoma Cell Migration

(2010) N. Bergelin et al.   ENDOCRINOLOGY

Finding the right niche: B-cell migration in the early phases of T-dependent antibody responses

(2010) J. P. Pereira et al.   INTERNATIONAL IMMUNOLOGY

Dental Pulp Stem Cell Migration

(2010) Cameron Howard et al.   JOURNAL OF ENDODONTICS

Role of Rho kinase in sphingosine 1-phosphate-mediated endothelial and smooth muscle cell migration and differentiation

(2010) Kevin A. Harvey et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

HDL and sphingosine-1-phosphate activate stat3 in prostate cancer DU145 cells via ERK1/2 and S1P receptors, and promote cell migration and invasion

(2010) Yoshitaka Sekine et al.   PROSTATE

Differential regulation of sphingosine kinases 1 and 2 in lung injury

(2009) Raj Wadgaonkar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

S1P/S1P1 signaling stimulates cell migration and invasion in Wilms tumor

(2009) Mei-Hong Li et al.   CANCER LETTERS

When the Sphingosine Kinase 1/Sphingosine 1-Phosphate Pathway Meets Hypoxia Signaling: New Targets for Cancer Therapy

(2009) I. Ader et al.   CANCER RESEARCH

Targeting Sphingosine Kinase 1 Inhibits Akt Signaling, Induces Apoptosis, and Suppresses Growth of Human Glioblastoma Cells and Xenografts

(2009) D. Kapitonov et al.   CANCER RESEARCH

Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis

(2009) Masaru Ishii et al.   NATURE

TGF-β1–induced migration of bone mesenchymal stem cells couples bone resorption with formation

(2009) Yi Tang et al.   NATURE MEDICINE

The vascular S1P gradient—Cellular sources and biological significance

(2008) T HLA   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

A selective sphingosine kinase 1 inhibitor integrates multiple molecular therapeutic targets in human leukemia

(2008) S. W. Paugh et al.   BLOOD

Distinct roles of sphingosine kinases 1 and 2 in human mast-cell functions

(2008) C. A. Oskeritzian et al.   BLOOD

Sphingosine kinase 1/S1P receptor signaling axis controls glial proliferation in mice with Sandhoff disease

(2008) Yun-Ping Wu et al.   HUMAN MOLECULAR GENETICS

Dendritic cell PAR1–S1P3 signalling couples coagulation and inflammation

(2008) Frank Niessen et al.   NATURE

"Inside-Out" Signaling of Sphingosine-1-Phosphate: Therapeutic Targets

(2008) K. Takabe et al.   PHARMACOLOGICAL REVIEWS

Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate

(2008) L. Pederson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA