p53 and Translation Attenuation Regulate Distinct Cell Cycle Checkpoints during Endoplasmic Reticulum (ER) Stress

Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity and Dynamics of Mammalian Proteomes

(2011) Nicholas T. Ingolia et al.   CELL

A quantitative method for detection of spliced X-box binding protein-1 (XBP1) mRNA as a measure of endoplasmic reticulum (ER) stress

(2011) Annemarie van Schadewijk et al.   CELL STRESS & CHAPERONES

A systematic RNAi synthetic interaction screen reveals a link between p53 and snoRNP assembly

(2011) Dragomir B. Krastev et al.   NATURE CELL BIOLOGY

Inhibition of p53 expression by peptide-conjugated phosphorodiamidate morpholino oligomers sensitizes human cancer cells to chemotherapeutic drugs

(2011) W Ma et al.   ONCOGENE

Effect of mutations on the p53 IRES RNA structure: Implications for de-regulation of the synthesis of p53 isoforms

(2011) Richa Grover et al.   RNA Biology

Polypyrimidine tract binding protein regulates IRES-mediated translation of p53 isoforms

(2010) Richa Grover et al.   CELL CYCLE

Mcl-1 downregulation by pro-inflammatory cytokines and palmitate is an early event contributing to β-cell apoptosis

(2010) F Allagnat et al.   CELL DEATH AND DIFFERENTIATION

Diabetes as a disease of endoplasmic reticulum stress

(2010) Sally E. Thomas et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Impaired tissue growth is mediated by checkpoint kinase 1 (CHK1) in the integrated stress response

(2010) E. Malzer et al.   JOURNAL OF CELL SCIENCE

Endoplasmic Reticulum Stress Induces G2 Cell-Cycle Arrest via mRNA Translation of the p53 Isoform p53/47

(2010) Karima Bourougaa et al.   MOLECULAR CELL

Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin

(2010) Tilman Schneider-Poetsch et al.   Nature Chemical Biology

p53 isoforms gain functions

(2010) V Olivares-Illana et al.   ONCOGENE

PERK promotes cancer cell proliferation and tumor growth by limiting oxidative DNA damage

(2010) E Bobrovnikova-Marjon et al.   ONCOGENE

ATM blocks tunicamycin-induced endoplasmic reticulum stress

(2009) Long He et al.   FEBS LETTERS

Checkpoint Kinase 1 Down-Regulation by an Inducible Small Interfering RNA Expression System Sensitized In vivo Tumors to Treatment with 5-Fluorouracil

(2008) M. Ganzinelli et al.   CLINICAL CANCER RESEARCH

Chop deletion reduces oxidative stress, improves β cell function, and promotes cell survival in multiple mouse models of diabetes

(2008) Benbo Song et al.   JOURNAL OF CLINICAL INVESTIGATION

Adapting Proteostasis for Disease Intervention

(2008) William E. Balch et al.   SCIENCE