Meclizine Inhibits Mitochondrial Respiration through Direct Targeting of Cytosolic Phosphoethanolamine Metabolism

Regulation of Phosphatidylethanolamine Homeostasis — The Critical Role of CTP:Phosphoethanolamine Cytidylyltransferase (Pcyt2)

(2013) Zvezdan Pavlovic et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Biochemical characterization ofPlasmodium falciparumCTP:phosphoethanolamine cytidylyltransferase shows that only one of the two cytidylyltransferase domains is active

(2012) Sweta Maheshwari et al.   BIOCHEMICAL JOURNAL

Phosphatidylethanolamine Deficiency in Mammalian Mitochondria Impairs Oxidative Phosphorylation and Alters Mitochondrial Morphology

(2012) Guergana Tasseva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphatidylethanolamine and Cardiolipin Differentially Affect the Stability of Mitochondrial Respiratory Chain Supercomplexes

(2012) Lena Böttinger et al.   JOURNAL OF MOLECULAR BIOLOGY

Mitochondrial disorders as windows into an ancient organelle

(2012) Scott B. Vafai et al.   NATURE

Meclizine Metabolism and Pharmacokinetics: Formulation on Its Absorption

(2011) Zhijun Wang et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Metabolite profiling of antidepressant drug action reveals novel drug targets beyond monoamine elevation

(2011) C Webhofer et al.   Translational Psychiatry

Ethanolamine is a novel STAT-3 dependent cardioprotective agent

(2010) Roisin F. Kelly et al.   BASIC RESEARCH IN CARDIOLOGY

Meclizine is neuroprotective in models of Huntington's disease

(2010) V. M. Gohil et al.   HUMAN MOLECULAR GENETICS

Mitochondrial and Nuclear Genomic Responses to Loss ofLRPPRCExpression

(2010) Vishal M. Gohil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis

(2010) Vishal M Gohil et al.   NATURE BIOTECHNOLOGY

A plasma signature of human mitochondrial disease revealed through metabolic profiling of spent media from cultured muscle cells

(2010) O. Shaham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Development of a Metabolic Disease Phenotype in CTP:Phosphoethanolamine Cytidylyltransferase-deficient Mice

(2009) Morgan D. Fullerton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The ethanolamine branch of the Kennedy pathway is essential in the bloodstream form ofTrypanosoma brucei

(2009) Federica Gibellini et al.   MOLECULAR MICROBIOLOGY

Stimulation of the human CTP:phosphoethanolamine cytidylyltransferase gene by early growth response protein 1

(2008) Lin Zhu et al.   JOURNAL OF LIPID RESEARCH

Thematic Review Series: Glycerolipids.Phosphatidylserine and phosphatidylethanolamine in mammalian cells: two metabolically related aminophospholipids

(2008) Jean E. Vance   JOURNAL OF LIPID RESEARCH

Mitochondrial Medicine: Pharmacological targeting of mitochondria in disease

(2007) J S Armstrong   BRITISH JOURNAL OF PHARMACOLOGY