Endogenous Interleukin-1β in Neuropathic Rats Enhances Glutamate Release from the Primary Afferents in the Spinal Dorsal Horn through Coupling with PresynapticN-Methyl-d-aspartic Acid Receptors

Endogenous activation of presynaptic NMDA receptors enhances glutamate release from the primary afferents in the spinal dorsal horn in a rat model of neuropathic pain

(2013) Xisheng Yan et al.   JOURNAL OF PHYSIOLOGY-LONDON

The critical role of spinal ceramide in the development of partial sciatic nerve ligation-induced neuropathic pain in mice

(2012) Yuka Kobayashi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Role of bovine adrenal medulla 22 (BAM22) in the pathogenesis of neuropathic pain in rats with spinal nerve ligation

(2012) Tingjun Chen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Metabolomics implicates altered sphingolipids in chronic pain of neuropathic origin

(2012) Gary J. Patti et al.   Nature Chemical Biology

Interleukin-1β causes synaptic hyperexcitability in multiple sclerosis

(2011) Silvia Rossi et al.   ANNALS OF NEUROLOGY

Intraplantar-injected ceramide in rats induces hyperalgesia through an NF-κB- and p38 kinase-dependent cyclooxygenase 2/prostaglandin E2 pathway

(2011) Tim Doyle et al.   FASEB JOURNAL

Resolving TRPV1- and TNF- -Mediated Spinal Cord Synaptic Plasticity and Inflammatory Pain with Neuroprotectin D1

(2011) C.-K. Park et al.   JOURNAL OF NEUROSCIENCE

Multiple Targets of  -Opioid Receptor-Mediated Presynaptic Inhibition at Primary Afferent A - and C-Fibers

(2011) B. Heinke et al.   JOURNAL OF NEUROSCIENCE

Impaired Glial Glutamate Uptake Induces Extrasynaptic Glutamate Spillover in the Spinal Sensory Synapses of Neuropathic Rats

(2010) Hui Nie et al.   JOURNAL OF NEUROPHYSIOLOGY

Counter-Regulation of Opioid Analgesia by Glial-Derived Bioactive Sphingolipids

(2010) C. Muscoli et al.   JOURNAL OF NEUROSCIENCE

Interactions between the immune and nervous systems in pain

(2010) Ke Ren et al.   NATURE MEDICINE

Presynaptic NMDARs in the Hippocampus Facilitate Transmitter Release at Theta Frequency

(2010) Lindsay McGuinness et al.   NEURON

Peripheral inflammation induces tumor necrosis factor dependent AMPA receptor trafficking and Akt phosphorylation in spinal cord in addition to pain behavior

(2010) Jeong Il Choi et al.   PAIN

Cellular and Molecular Mechanisms of Pain

(2009) Allan I. Basbaum et al.   CELL

Peptidoglycan Induces Cyclooxygenase-2 Expression in Macrophages by Activating the Neutral Sphingomyelinase-Ceramide Pathway

(2009) Bing-Chang Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glutamate Transporters Prevent Excessive Activation of NMDA Receptors and Extrasynaptic Glutamate Spillover in the Spinal Dorsal Horn

(2009) Hui Nie et al.   JOURNAL OF NEUROPHYSIOLOGY

Signal Transduction Mechanisms Underlying Group I Mglur-Mediated Increase in Frequency and Amplitude of Spontaneous EPSCs in the Spinal Trigeminal Subnucleus Oralis of the Rat

(2009) Ji-Hyeon Song et al.   Molecular Pain

Plasticity in Expression of the Glutamate Transporters GLT-1 and GLAST in Spinal Dorsal Horn Glial Cells following Partial Sciatic Nerve Ligation

(2009) Wen-Jun Xin et al.   Molecular Pain

Induction of Synaptic Long-Term Potentiation After Opioid Withdrawal

(2009) R. Drdla et al.   SCIENCE

A novel non-transcriptional pathway mediates the proconvulsive effects of interleukin-1 

(2008) S. Balosso et al.   BRAIN

Presynaptic and Postsynaptic Amplifications of Neuropathic Pain in the Anterior Cingulate Cortex

(2008) H. Xu et al.   JOURNAL OF NEUROSCIENCE

Cytokine Mechanisms of Central Sensitization: Distinct and Overlapping Role of Interleukin-1 , Interleukin-6, and Tumor Necrosis Factor-  in Regulating Synaptic and Neuronal Activity in the Superficial Spinal Cord

(2008) Y. Kawasaki et al.   JOURNAL OF NEUROSCIENCE

Nociceptors Are Interleukin-1  Sensors

(2008) A. M. Binshtok et al.   JOURNAL OF NEUROSCIENCE

Spinal Ceramide Modulates the Development of Morphine Antinociceptive Tolerance via Peroxynitrite-Mediated Nitroxidative Stress and Neuroimmune Activation

(2008) M. M. Ndengele et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Differential effects of interleukin-1 alpha and beta on interleukin-6 and chemokine synthesis in neurones

(2008) Niki Tsakiri et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Principles of bioactive lipid signalling: lessons from sphingolipids

(2008) Yusuf A. Hannun et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Pathological and protective roles of glia in chronic pain

(2008) Erin D. Milligan et al.   NATURE REVIEWS NEUROSCIENCE

Dendritic NMDA Receptors Activate Axonal Calcium Channels

(2008) Jason M. Christie et al.   NEURON

Interleukin-1alpha has antiallodynic and antihyperalgesic activities in a rat neuropathic pain model

(2008) Joanna Mika et al.   PAIN

IL-1β signaling is required for mechanical allodynia induced by nerve injury and for the ensuing reduction in spinal cord neuronal GRK2

(2007) Wendy Kleibeuker et al.   BRAIN BEHAVIOR AND IMMUNITY

IL-1ra alleviates inflammatory hyperalgesia through preventing phosphorylation of NMDA receptor NR-1 subunit in rats

(2007) Rui-Xin Zhang et al.   PAIN