Structural Insights into Aβ42 Oligomers Using Site-directed Spin Labeling

Structural origin of polymorphism of Alzheimer's amyloid β-fibrils

(2012) Audrey Agopian et al.   BIOCHEMICAL JOURNAL

High-Resolution Structure of a Protein Spin-Label in a Solvent-Exposed β-Sheet and Comparison with DEER Spectroscopy

(2012) Timothy F. Cunningham et al.   BIOCHEMISTRY

Mapping Molecular Flexibility of Proteins with Site-Directed Spin Labeling: A Case Study of Myoglobin

(2012) Carlos J. López et al.   BIOCHEMISTRY

Protein Misfolded Oligomers: Experimental Approaches, Mechanism of Formation, and Structure-Toxicity Relationships

(2012) Francesco Bemporad et al.   CHEMISTRY & BIOLOGY

A comparative analysis of the aggregation behavior of amyloid-β peptide variants

(2012) Annelies Vandersteen et al.   FEBS LETTERS

Solid-support Electron Paramagnetic Resonance (EPR) Studies of Aβ40 Monomers Reveal a Structured State with Three Ordered Segments

(2012) Lei Gu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

(2012) Iryna Benilova et al.   NATURE NEUROSCIENCE

Prion Domain of Yeast Ure2 Protein Adopts a Completely Disordered Structure: A Solid-Support EPR Study

(2012) Sam Ngo et al.   PLoS One

Molecular basis of  -amyloid oligomer recognition with a conformational antibody fragment

(2012) I. Morgado et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toxic fibrillar oligomers of amyloid-  have cross-  structure

(2012) J. C. Stroud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atomic View of a Toxic Amyloid Small Oligomer

(2012) Arthur Laganowsky et al.   SCIENCE

Solid-State NMR Studies of Amyloid Fibril Structure

(2011) Robert Tycko   Annual Review of Physical Chemistry

Structural investigation of porcine stomach mucin by X-ray fiber diffraction and homology modeling

(2011) K. Veluraja et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Key residues for the oligomerization of Aβ42 protein in Alzheimer’s disease

(2011) Sam Ngo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Polymorphic Triple β-Sheet Structures Contribute to Amide Hydrogen/Deuterium (H/D) Exchange Protection in the Alzheimer Amyloid β42 Peptide

(2011) Buyong Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of the Amyloid-  p3 Fragment Provides a Model for Oligomer Formation in Alzheimer's Disease

(2011) V. A. Streltsov et al.   JOURNAL OF NEUROSCIENCE

Characteristics of Amyloid-Related Oligomers Revealed by Crystal Structures of Macrocyclic β-Sheet Mimics

(2011) Cong Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Toward the Fourth Dimension of Membrane Protein Structure: Insight into Dynamics from Spin-Labeling EPR Spectroscopy

(2011) Hassane S. Mchaourab et al.   STRUCTURE

Alzheimer's Disease

(2011) D. J. Selkoe   Cold Spring Harbor Perspectives in Biology

Transformation of amyloid β(1–40) oligomers into fibrils is characterized by a major change in secondary structure

(2010) Rabia Sarroukh et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Polymorphic C-terminal β-Sheet Interactions Determine the Formation of Fibril or Amyloid β-derived Diffusible Ligand-like Globulomer for the Alzheimer Aβ42 Dodecamer

(2010) Buyong Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Generation and Therapeutic Efficacy of Highly Oligomer-Specific  -Amyloid Antibodies

(2010) H. Hillen et al.   JOURNAL OF NEUROSCIENCE

Structural conversion of neurotoxic amyloid-β1–42 oligomers to fibrils

(2010) Mahiuddin Ahmed et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Proteases and Proteolysis in Alzheimer Disease: A Multifactorial View on the Disease Process

(2010) Bart De Strooper   PHYSIOLOGICAL REVIEWS

Stabilization of neurotoxic Alzheimer amyloid-  oligomers by protein engineering

(2010) A. Sandberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Beta-barrel models of soluble amyloid beta oligomers and annular protofibrils

(2010) Yinon Shafrir et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Antiparallel β-sheet: a signature structure of the oligomeric amyloid β-peptide

(2009) Emilie Cerf et al.   BIOCHEMICAL JOURNAL

Structural Characterization of a Soluble Amyloid β-Peptide Oligomer

(2009) Liping Yu et al.   BIOCHEMISTRY

Structural Classification of Toxic Amyloid Oligomers

(2008) Charles G. Glabe   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid β-Protein Assembly and Alzheimer Disease

(2008) Robin Roychaudhuri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oligomeric and fibrillar species of β-amyloid (Aβ42) both impair mitochondrial function in P301L tau transgenic mice

(2008) Anne Eckert et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Amyloid   Oligomers (A 1-42 Globulomer) Suppress Spontaneous Synaptic Activity by Inhibition of P/Q-Type Calcium Currents

(2008) V. Nimmrich et al.   JOURNAL OF NEUROSCIENCE

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE

Aβ-globulomers are formed independently of the fibril pathway

(2008) Gerald P. Gellermann et al.   NEUROBIOLOGY OF DISEASE

Stabilization of a β-hairpin in monomeric Alzheimer's amyloid-β peptide inhibits amyloid formation

(2008) Wolfgang Hoyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fibrils with parallel in-register structure constitute a major class of amyloid fibrils: molecular insights from electron paramagnetic resonance spectroscopy

(2008) Martin Margittai et al.   QUARTERLY REVIEWS OF BIOPHYSICS

FTIR reveals structural differences between native β-sheet proteins and amyloid fibrils

(2004) Giorgia Zandomeneghi et al.   PROTEIN SCIENCE