Lipids as Tumoricidal Components of Human α-Lactalbumin Made Lethal to Tumor Cells (HAMLET)

A Unifying Mechanism for Cancer Cell Death through Ion Channel Activation by HAMLET

(2013) Petter Storm et al.   PLoS One

Glycine Decarboxylase Activity Drives Non-Small Cell Lung Cancer Tumor-Initiating Cells and Tumorigenesis

(2012) Wen Cai Zhang et al.   CELL

Glucose-Independent Glutamine Metabolism via TCA Cycling for Proliferation and Survival in B Cells

(2012) Anne Le et al.   Cell Metabolism

HAMLET Forms Annular Oligomers When Deposited with Phospholipid Monolayers

(2012) Anne Baumann et al.   JOURNAL OF MOLECULAR BIOLOGY

Dysregulation of fatty acid synthesis and glycolysis in non-Hodgkin lymphoma

(2012) A. P. Bhatt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oleic acid is a key cytotoxic component of HAMLET-like complexes

(2011) Sergei E. Permyakov et al.   BIOLOGICAL CHEMISTRY

Cytotoxic complexes of sodium oleate with β-lactoglobulin

(2011) Kamila Lišková et al.   EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY

Conserved features of cancer cells define their sensitivity to HAMLET-induced death; c-Myc and glycolysis

(2011) P Storm et al.   ONCOGENE

Prediction of protein secondary structure from circular dichroism using theoretically derived spectra

(2011) Caroline Louis-Jeune et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Effect of Denaturation of α-Lactalbumin on the Formation of BAMLET (Bovine α-Lactalbumin Made Lethal to Tumor Cells)

(2010) Kamila Lišková et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

HAMLET Treatment Delays Bladder Cancer Development

(2010) Ann-Kristin Mossberg et al.   JOURNAL OF UROLOGY

Lipoprotein Complex of Equine Lysozyme with Oleic Acid (ELOA) Interactions with the Plasma Membrane of Live Cells

(2010) Vladana Vukojević et al.   LANGMUIR

HAMLET Interacts with Lipid Membranes and Perturbs Their Structure and Integrity

(2010) Ann-Kristin Mossberg et al.   PLoS One

Monoacylglycerol Lipase Regulates a Fatty Acid Network that Promotes Cancer Pathogenesis

(2009) Daniel K. Nomura et al.   CELL

The oleic acid complexes of proteolytic fragments of α-lactalbumin display apoptotic activity

(2009) Serena Tolin et al.   FEBS Journal

Protein oligomerization induced by oleic acid at the solid-liquid interface - equine lysozyme cytotoxic complexes

(2009) Kristina Wilhelm et al.   FEBS Journal

Interaction of antitumor α-lactalbumin—oleic acid complexes with artificial and natural membranes

(2009) Olga M. Zherelova et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

α-Lactalbumin, Engineered to be Nonnative and Inactive, Kills Tumor Cells when in Complex with Oleic Acid: A New Biological Function Resulting from Partial Unfolding

(2009) Jenny Pettersson-Kastberg et al.   JOURNAL OF MOLECULAR BIOLOGY

Changes in Proteasome Structure and Function Caused by HAMLET in Tumor Cells

(2009) Lotta Gustafsson et al.   PLoS One

Can misfolded proteins be beneficial? The HAMLET case

(2008) Jenny Pettersson-Kastberg et al.   ANNALS OF MEDICINE

Cancer Cell Metabolism: Warburg and Beyond

(2008) Peggy P. Hsu et al.   CELL

HAMLET (human α-lactalbumin made lethal to tumor cells) triggers autophagic tumor cell death

(2008) Sonja Aits et al.   INTERNATIONAL JOURNAL OF CANCER