Myosin Regulatory Light Chain (RLC) Phosphorylation Change as a Modulator of Cardiac Muscle Contraction in Disease

Mouse and computational models link Mlc2v dephosphorylation to altered myosin kinetics in early cardiac disease

(2012) Farah Sheikh et al.   JOURNAL OF CLINICAL INVESTIGATION

Smooth muscle myosin light chain kinase efficiently phosphorylates serine 15 of cardiac myosin regulatory light chain

(2011) Matthew P. Josephson et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The effect of myosin RLC phosphorylation in normal and cardiomyopathic mouse hearts

(2011) Priya Muthu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

FRET characterisation for cross-bridge dynamics in single-skinned rigor muscle fibres

(2010) Valentina Caorsi et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Cardiac Myosin Light Chain Kinase Is Necessary for Myosin Regulatory Light Chain Phosphorylation and Cardiac Performancein Vivo

(2010) Peiguo Ding et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of contraction in mammalian striated muscles—the plotthick-ens: Figure 1.

(2010) Richard L. Moss et al.   JOURNAL OF GENERAL PHYSIOLOGY

Differential roles of regulatory light chain and myosin binding protein-C phosphorylations in the modulation of cardiac force development

(2010) Brett A. Colson et al.   JOURNAL OF PHYSIOLOGY-LONDON

A Novel, In-solution Separation of Endogenous Cardiac Sarcomeric Proteins and Identification of Distinct Charged Variants of Regulatory Light Chain

(2010) Sarah B. Scruggs et al.   MOLECULAR & CELLULAR PROTEOMICS

The molecular effects of skeletal muscle myosin regulatory light chain phosphorylation

(2009) Michael J. Greenberg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Diastolic dysfunction in familial hypertrophic cardiomyopathy transgenic model mice

(2009) Theodore P. Abraham et al.   CARDIOVASCULAR RESEARCH

Overexpression of Myosin Phosphatase Reduces Ca2+ Sensitivity of Contraction and Impairs Cardiac Function

(2009) Hideo Mizutani et al.   CIRCULATION JOURNAL

Cardiac Myosin Is a Substrate for Zipper-interacting Protein Kinase (ZIPK)

(2009) Audrey N. Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of T-tubules and other changes to surface topography in ventricular myocytes from failing human and rat heart

(2009) A. R. Lyon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The molecular phenotype of human cardiac myosin associated with hypertrophic obstructive cardiomyopathy

(2008) Adam M. Jacques et al.   CARDIOVASCULAR RESEARCH

Malignant familial hypertrophic cardiomyopathy D166V mutation in the ventricular myosin regulatory light chain causes profound effects in skinned and intact papillary muscle fibers from transgenic mice

(2008) W. Glenn L. Kerrick et al.   FASEB JOURNAL

Myosin Regulatory Light Chain Phosphorylation Attenuates Cardiac Hypertrophy

(2008) Jian Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ablation of Ventricular Myosin Regulatory Light Chain Phosphorylation in Mice Causes Cardiac Dysfunctionin Situand Affects Neighboring Myofilament Protein Phosphorylation

(2008) Sarah B. Scruggs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY