Ca2+Influx through Store-operated Ca2+Channels Reduces Alzheimer Disease β-Amyloid Peptide Secretion

Presenilins and  -Secretase: Structure, Function, and Role in Alzheimer Disease

(2013) B. De Strooper et al.   Cold Spring Harbor Perspectives in Medicine

Trafficking and Proteolytic Processing of APP

(2013) C. Haass et al.   Cold Spring Harbor Perspectives in Medicine

2012 Alzheimer’s disease facts and figures

(2012)   Alzheimers & Dementia

Novel G S-Protein Signaling Associated with Membrane-Tethered Amyloid Precursor Protein Intracellular Domain

(2012) C. Deyts et al.   JOURNAL OF NEUROSCIENCE

Dysregulation of Ca2+ signaling in astrocytes from mice lacking amyloid precursor protein

(2011) Cristina I. Linde et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Loss of Cleavage at β′-Site Contributes to Apparent Increase in β-Amyloid Peptide (Aβ) Secretion by β-Secretase (BACE1)-Glycosylphosphatidylinositol (GPI) Processing of Amyloid Precursor Protein

(2011) Kulandaivelu S. Vetrivel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stanniocalcin 2 Is a Negative Modulator of Store-Operated Calcium Entry

(2011) W. Zeiger et al.   MOLECULAR AND CELLULAR BIOLOGY

Transgenic neuronal overexpression reveals that stringently regulated p23 expression is critical for coordinated movement in mice

(2011) Ping Gong et al.   Molecular Neurodegeneration

Mutation Analysis of the Presenilin 1 N-terminal Domain Reveals a Broad Spectrum of γ-Secretase Activity toward Amyloid Precursor Protein and Other Substrates

(2010) Ping Gong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium Signaling and Amyloid Toxicity in Alzheimer Disease

(2010) Angelo Demuro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reduced Alzheimer's Disease  -Amyloid Deposition in Transgenic Mice Expressing S-Palmitoylation-Deficient APH1aL and Nicastrin

(2010) X. Meckler et al.   JOURNAL OF NEUROSCIENCE

Inhibition of neuronal calcium oscillations by cell surface APP phosphorylated on T668

(2010) Susana Ferrao Santos et al.   NEUROBIOLOGY OF AGING

FAD Mutations in Amyloid Precursor Protein Do Not Directly Perturb Intracellular Calcium Homeostasis

(2010) Emily Stieren et al.   PLoS One

The CRAC Channel Activator STIM1 Binds and Inhibits L-Type Voltage-Gated Calcium Channels

(2010) C. Y. Park et al.   SCIENCE

The Calcium Store Sensor, STIM1, Reciprocally Controls Orai and CaV1.2 Channels

(2010) Y. Wang et al.   SCIENCE

Synaptic NMDA Receptor Activation Stimulates  -Secretase Amyloid Precursor Protein Processing and Inhibits Amyloid-  Production

(2009) S. E. Hoey et al.   JOURNAL OF NEUROSCIENCE

The  -Secretase Enzyme BACE in Health and Alzheimer's Disease: Regulation, Cell Biology, Function, and Therapeutic Potential

(2009) R. Vassar et al.   JOURNAL OF NEUROSCIENCE

Presenilins are essential for regulating neurotransmitter release

(2009) Chen Zhang et al.   NATURE

Disrupted intracellular calcium regulates BACE1 gene expression via nuclear factor of activated T cells 1 (NFAT 1) signaling

(2008) Hyun Jin Cho et al.   AGING CELL

Store-dependent and -independent Modes Regulating Ca2+Release-activated Ca2+Channel Activity of Human Orai1 and Orai3

(2008) Shenyuan L. Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

2-Aminoethoxydiphenyl Borate Alters Selectivity of Orai3 Channels by Increasing Their Pore Size

(2008) Rainer Schindl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alzheimer Disease Aβ Production in the Absence ofS-Palmitoylation-dependent Targeting of BACE1 to Lipid Rafts

(2008) Kulandaivelu S. Vetrivel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Complex Actions of 2-Aminoethyldiphenyl Borate on Store-operated Calcium Entry

(2008) Wayne I. DeHaven et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SERCA pump activity is physiologically regulated by presenilin and regulates amyloid β production

(2008) Kim N. Green et al.   JOURNAL OF CELL BIOLOGY

2-Aminoethoxydiphenyl borate directly facilitates and indirectly inhibits STIM1-dependent gating of CRAC channels

(2008) Christine Peinelt et al.   JOURNAL OF PHYSIOLOGY-LONDON

Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation

(2008) Riina M. Luik et al.   NATURE

Mechanism of Ca2+ Disruption in Alzheimer's Disease by Presenilin Regulation of InsP3 Receptor Channel Gating

(2008) King-Ho Cheung et al.   NEURON

APPswe mutation increases the frequency of spontaneous Ca2+-oscillations in rat hippocampal neurons

(2008) Ewa Kloskowska et al.   NEUROSCIENCE LETTERS