The E295K Cancer Variant of Human Polymerase β Favors the Mismatch Conformational Pathway during Nucleotide Selection

Observing a DNA Polymerase Choose Right from Wrong

(2013) Bret D. Freudenthal et al.   CELL

dNTP-dependent Conformational Transitions in the Fingers Subdomain of Klentaq1 DNA Polymerase

(2013) Paul J. Rothwell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HumanPOLBGene Is Mutated in High Percentage of Colorectal Tumors

(2012) Katherine A. Donigan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Substrate-Dependent Millisecond Domain Motions in DNA Polymerase β

(2012) Rebecca B. Berlow et al.   JOURNAL OF MOLECULAR BIOLOGY

Unfavorable Electrostatic and Steric Interactions in DNA Polymerase β E295K Mutant Interfere with the Enzyme’s Pathway

(2012) Yunlang Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Watching DNA polymerase η make a phosphodiester bond

(2012) Teruya Nakamura et al.   NATURE

Structures of dNTP Intermediate States during DNA Polymerase Active Site Assembly

(2012) Bret D. Freudenthal et al.   STRUCTURE

Perspective: pre-chemistry conformational changes in DNA polymerase mechanisms

(2012) Tamar Schlick et al.   THEORETICAL CHEMISTRY ACCOUNTS

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The Structure of a High Fidelity DNA Polymerase Bound to a Mismatched Nucleotide Reveals an “Ajar” Intermediate Conformation in the Nucleotide Selection Mechanism

(2011) Eugene Y. Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metal-induced DNA translocation leads to DNA polymerase conformational activation

(2011) Thomas W. Kirby et al.   NUCLEIC ACIDS RESEARCH

Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis

(2011) W. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

DNA Polymerase β Substrate Specificity

(2009) William A. Beard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structures of DNA Polymerase β with Active-Site Mismatches Suggest a Transient Abasic Site Intermediate during Misincorporation

(2008) Vinod K. Batra et al.   MOLECULAR CELL

3DNA: a versatile, integrated software system for the analysis, rebuilding and visualization of three-dimensional nucleic-acid structures

(2008) Xiang-Jun Lu et al.   Nature Protocols