标题
Effects of Isoform-selective Phosphatidylinositol 3-Kinase Inhibitors on Osteoclasts
作者
关键词
-
出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 288, Issue 49, Pages 35346-35357
出版商
American Society for Biochemistry & Molecular Biology (ASBMB)
发表日期
2013-10-17
DOI
10.1074/jbc.m113.507525
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Specific inhibition of PI3K p110δ inhibits CSF-1-induced macrophage spreading and invasive capacity
- (2013) Kellie A. Mouchemore et al. FEBS Journal
- The phosphoinositide 3'-kinase delta inhibitor, CAL-101, inhibits B-cell receptor signaling and chemokine networks in chronic lymphocytic leukemia
- (2011) J. Hoellenriegel et al. BLOOD
- Progress in the Preclinical Discovery and Clinical Development of Class I and Dual Class I/IV Phosphoinositide 3-Kinase (PI3K) Inhibitors
- (2011) S. J. Shuttleworth et al. CURRENT MEDICINAL CHEMISTRY
- PI3K and Chemotaxis: A Priming Issue?
- (2011) P. V. Afonso et al. Science Signaling
- CAL-101, a p110 selective phosphatidylinositol-3-kinase inhibitor for the treatment of B-cell malignancies, inhibits PI3K signaling and cellular viability
- (2010) B. J. Lannutti et al. BLOOD
- Lysophosphatidic Acid Signals through Multiple Receptors in Osteoclasts to Elevate Cytosolic Calcium Concentration, Evoke Retraction, and Promote Cell Survival
- (2010) Danielle M. Lapierre et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Loss of Cbl-Phosphatidylinositol 3-Kinase Interaction Perturbs RANKL-mediated Signaling, Inhibiting Bone Resorption and Promoting Osteoclast Survival
- (2010) Naga Suresh Adapala et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phosphoinositide 3-kinase δ regulates membrane fission of Golgi carriers for selective cytokine secretion
- (2010) Pei Ching Low et al. JOURNAL OF CELL BIOLOGY
- The emerging mechanisms of isoform-specific PI3K signalling
- (2010) Bart Vanhaesebroeck et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Important roles of PI3K in osteoclastogenesis and bone homeostasis
- (2010) H. Kang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Activity of any class IA PI3K isoform can sustain cell proliferation and survival
- (2010) L. C. Foukas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The PI3K Isoforms p110 and p110 Are Essential for Pre-B Cell Receptor Signaling and B Cell Development
- (2010) F. Ramadani et al. Science Signaling
- Evidence for a role for the p110-α isoform of PI3K in skeletal function
- (2009) Andrew Grey et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Targeting the phosphoinositide 3-kinase pathway in cancer
- (2009) Pixu Liu et al. NATURE REVIEWS DRUG DISCOVERY
- Regulation of phosphoinositide 3-kinase expression in health and disease
- (2009) Klaartje Kok et al. TRENDS IN BIOCHEMICAL SCIENCES
- The Osteoclast: Friend or Foe?
- (2008) Deborah V. Novack et al. Annual Review of Pathology-Mechanisms of Disease
- Rho GTPases in osteoclasts: Orchestrators of podosome arrangement
- (2008) S ORY et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Actin cytoskeletal organisation in osteoclasts: A model to decipher transmigration and matrix degradation
- (2008) F SALTEL et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Activation of P2X7 receptors causes isoform-specific translocation of protein kinase C in osteoclasts
- (2008) S. Armstrong et al. JOURNAL OF CELL SCIENCE
- Distinct roles of class IA PI3K isoforms in primary and immortalised macrophages
- (2008) E. A. Papakonstanti et al. JOURNAL OF CELL SCIENCE
- The Identification of 2-(1H-Indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a Potent, Selective, Orally Bioavailable Inhibitor of Class I PI3 Kinase for the Treatment of Cancer†
- (2008) Adrian J. Folkes et al. JOURNAL OF MEDICINAL CHEMISTRY
- The p110 isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110
- (2008) J. Guillermet-Guibert et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting phosphoinositide 3-kinase—Moving towards therapy
- (2007) Romina Marone et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started