T-cell Receptor Specificity Maintained by Altered Thermodynamics

Different affinity windows for virus and cancer-specific T-cell receptors: Implications for therapeutic strategies

(2012) Milos Aleksic et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interplay between T Cell Receptor Binding Kinetics and the Level of Cognate Peptide Presented by Major Histocompatibility Complexes Governs CD8+T Cell Responsiveness

(2012) Melita Irving et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TCR/pMHC Optimized Protein crystallization Screen

(2012) Anna M. Bulek et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Cutting Edge: Evidence for a Dynamically Driven T Cell Signaling Mechanism

(2012) W. F. Hawse et al.   JOURNAL OF IMMUNOLOGY

Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes

(2012) Anna M Bulek et al.   NATURE IMMUNOLOGY

Monoclonal TCR-redirected tumor cell killing

(2012) Nathaniel Liddy et al.   NATURE MEDICINE

Modification of the carboxy-terminal flanking region of a universal influenza epitope alters CD4+ T-cell repertoire selection

(2012) David K. Cole et al.   Nature Communications

Minimal conformational plasticity enables TCR cross-reactivity to different MHC class II heterodimers

(2012) Christopher J. Holland et al.   Scientific Reports

Structural and biophysical determinants of αβ T-cell antigen recognition

(2011) John S. Bridgeman et al.   IMMUNOLOGY

A Single Autoimmune T Cell Receptor Recognizes More Than a Million Different Peptides

(2011) Linda Wooldridge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms

(2011) O. Y. Borbulevych et al.   JOURNAL OF IMMUNOLOGY

Disparate Degrees of Hypervariable Loop Flexibility Control T-Cell Receptor Cross-Reactivity, Specificity, and Binding Mechanism

(2011) Daniel R. Scott et al.   JOURNAL OF MOLECULAR BIOLOGY

Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia

(2011) David L. Porter et al.   NEW ENGLAND JOURNAL OF MEDICINE

Modification of MHC Anchor Residues Generates Heteroclitic Peptides That Alter TCR Binding and T Cell Recognition

(2010) D. K. Cole et al.   JOURNAL OF IMMUNOLOGY

Genetic and Structural Basis for Selection of a Ubiquitous T Cell Receptor Deployed in Epstein-Barr Virus Infection

(2010) John J. Miles et al.   PLoS Pathogens

xia2: an expert system for macromolecular crystallography data reduction

(2009) G. Winter   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Germ Line-governed Recognition of a Cancer Epitope by an Immunodominant Human T-cell Receptor

(2009) David K. Cole et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Bases for the Affinity-Driven Selection of a Public TCR against a Dominant Human Cytomegalovirus Epitope

(2009) S. Gras et al.   JOURNAL OF IMMUNOLOGY

Thermodynamics of T‐cell receptor–peptide/MHC interactions: progress and opportunities

(2008) Kathryn M. Armstrong et al.   JOURNAL OF MOLECULAR RECOGNITION

T cell receptor engagement of peptide-major histocompatibility complex class I does not modify CD8 binding

(2008) David K. Cole et al.   MOLECULAR IMMUNOLOGY

Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor

(2008) Angel Varela-Rohena et al.   NATURE MEDICINE